| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Lung Injury | D055371 | 33 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Adams LS et al. | Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. | 2006 | Evid Based Complement Alternat Med | pmid:16550232 |
| Wang TC et al. | Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest. | 2012 | Evid Based Complement Alternat Med | pmid:22693529 |
| Qi XF et al. | Bambusae caulis in Liquamen Suppresses the Expression of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine in Human Keratinocytes due to Antioxidant Effect. | 2012 | Evid Based Complement Alternat Med | pmid:21785648 |
| Im AR et al. | Scutellaria baicalensis Extracts and Flavonoids Protect Rat L6 Cells from Antimycin A-Induced Mitochondrial Dysfunction. | 2012 | Evid Based Complement Alternat Med | pmid:22969827 |
| Pan SY et al. | New perspectives on chinese herbal medicine (zhong-yao) research and development. | 2011 | Evid Based Complement Alternat Med | pmid:21785622 |
| Lo YC et al. | Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo. | 2012 | Evid Based Complement Alternat Med | pmid:22474505 |
| Nakamura N et al. | Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line. | 2003 | Exp. Eye Res. | pmid:12873450 |
| Lee H et al. | Flavonoid wogonin from medicinal herb is neuroprotective by inhibiting inflammatory activation of microglia. | 2003 | FASEB J. | pmid:12897065 |
| Fajol A et al. | Fibroblast growth factor (Fgf) 23 gene transcription depends on actin cytoskeleton reorganization. | 2016 | FEBS Lett. | pmid:26878191 |
| Liu J et al. | Screening of osteoanagenesis-active compounds from Scutellaria baicalensis Georgi by hPDLC/CMC-online-HPLC/MS. | 2014 | Fitoterapia | pmid:24393619 |
| Tian SS et al. | Flavonoids from the leaves of Carya cathayensis Sarg. inhibit vascular endothelial growth factor-induced angiogenesis. | 2014 | Fitoterapia | pmid:24096161 |
| Ku SK and Bae JS | Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. | 2014 | Fitoterapia | pmid:25020199 |
| Dong LL et al. | An enhanced preparation and purification of the major antioxidants baicalein and wogonin from Scutellariae radix. | 2012 | Food Chem | pmid:25683416 |
| Tu B et al. | Structure-activity relationship study between baicalein and wogonin by spectrometry, molecular docking and microcalorimetry. | 2016 | Food Chem | pmid:27132840 |
| Attia SM et al. | Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. | 2013 | Food Chem. Toxicol. | pmid:23872129 |
| Khan NM et al. | Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes. | 2017 | Free Radic. Biol. Med. | pmid:28237856 |
| Qian C et al. | Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells. | 2014 | Free Radic. Res. | pmid:24666416 |
| Matsunaga T et al. | Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. | 2012 | Front Pharmacol | pmid:22319498 |
| Park NI et al. | Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. | 2011 | Funct. Integr. Genomics | pmid:21538138 |
| Zhao K et al. | LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. | 2018 | Gene | pmid:29196258 |