Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Penile Induration D010411 4 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Ahn SH et al. Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. 2011 BMC Neurosci pmid:21810275
Samarghandian S et al. Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3. 2011 Clinics (Sao Paulo) pmid:21808878
Li Y and Martin RC Herbal medicine and hepatocellular carcinoma: applications and challenges. 2011 Evid Based Complement Alternat Med pmid:21799681
Qi XF et al. Bambusae caulis in Liquamen Suppresses the Expression of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine in Human Keratinocytes due to Antioxidant Effect. 2012 Evid Based Complement Alternat Med pmid:21785648
Pan SY et al. New perspectives on chinese herbal medicine (zhong-yao) research and development. 2011 Evid Based Complement Alternat Med pmid:21785622
Han S et al. Herbal extract THI improves metabolic abnormality in mice fed a high-fat diet. 2011 Nutr Res Pract pmid:21779522
Yang C et al. Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway. 2011 PLoS ONE pmid:21779360
Tan W et al. Anti-cancer natural products isolated from chinese medicinal herbs. 2011 Chin Med pmid:21777476
Polier G et al. Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. 2011 Cell Death Dis pmid:21776020
Su SY and Hsieh CL Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. 2011 Chin Med pmid:21740583
Yang DZ et al. Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. 2011 Talanta pmid:21726714
Li T et al. Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. 2011 Eur J Drug Metab Pharmacokinet pmid:21713461
Lei W et al. Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. 2010 Genet. Mol. Biol. pmid:21637484
Lim H et al. Effects of flavonoids on matrix metalloproteinase-13 expression of interleukin-1β-treated articular chondrocytes and their cellular mechanisms: inhibition of c-Fos/AP-1 and JAK/STAT signaling pathways. 2011 J. Pharmacol. Sci. pmid:21606625
Takahashi H et al. Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. 2011 Biochim. Biophys. Acta pmid:21596068
Lin CC et al. Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. 2011 Int. J. Oncol. pmid:21573491
Kimura Y and Sumiyoshi M Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. 2011 Eur. J. Pharmacol. pmid:21549115
Park NI et al. Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. 2011 Funct. Integr. Genomics pmid:21538138
Shi R et al. Simultaneous determination of five flavonoids from Scutellaria Barbata extract in rat plasma by LC-MS/MS and its application to pharmacokinetic study. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21514902
Jeong JC et al. Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death. 2011 J. Exp. Clin. Cancer Res. pmid:21501525