| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Lung Injury | D055371 | 33 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zeng H et al. | The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. | 2011 | J Ethnopharmacol | pmid:21466840 |
| Zhao L et al. | Developmental toxicity and genotoxicity studies of wogonin. | 2011 | Regul. Toxicol. Pharmacol. | pmid:21459121 |
| Gao J et al. | The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21457722 |
| Yu JS and Kim AK | Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. | 2011 | Mol. Cells | pmid:21448585 |
| Lee YM et al. | Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21436723 |
| Tang H et al. | The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells. | 2011 | BMC Biol. | pmid:21418589 |
| Mazzio EA et al. | The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | 2011 | Int J Mol Sci | pmid:21340000 |
| Kim EJ et al. | Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. | 2011 | Acta Physiol (Oxf) | pmid:21306568 |
| Chen P et al. | Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. | 2011 | Toxicology | pmid:21295103 |
| Yang L et al. | Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. | 2011 | Cancer Sci. | pmid:21244577 |
| Xie S et al. | Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. | 2011 | J. Pharm. Pharmacol. | pmid:21235595 |
| Gasiorowski K et al. | Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? | 2011 | CNS Neurol Disord Drug Targets | pmid:21222632 |
| Chow SE et al. | Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. | 2011 | Cancer Chemother. Pharmacol. | pmid:21207227 |
| Chen CY et al. | Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. | 2011 | J. Nutr. Biochem. | pmid:21190831 |
| Katrahalli U et al. | Interaction of bioactive coomassie brilliant blue g with protein: insights from spectroscopic methods. | 2010 Oct-Dec | Sci Pharm | pmid:21179322 |
| Ye G et al. | Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. | 2010 | Chem. Biodivers. | pmid:21162005 |
| Chen J et al. | Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. | 2011 | Biomed. Chromatogr. | pmid:21154891 |
| Kunwar RM et al. | Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. | 2010 | J Ethnobiol Ethnomed | pmid:21144003 |
| Jeong HJ et al. | Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism. | 2010 | J Neuroinflammation | pmid:21108840 |
| Wei L et al. | Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. | 2010 | J. Cell. Biochem. | pmid:21053277 |