Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Penile Induration D010411 4 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Kim EJ et al. Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. 2011 Acta Physiol (Oxf) pmid:21306568
Shia CS et al. Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. 2011 Evid Based Complement Alternat Med pmid:19737807
Chen CM et al. Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. 2011 Evid Based Complement Alternat Med pmid:19584080
Shi R et al. Simultaneous determination of five flavonoids from Scutellaria Barbata extract in rat plasma by LC-MS/MS and its application to pharmacokinetic study. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21514902
Gao J et al. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. 2011 Toxicol. Appl. Pharmacol. pmid:21457722
Park NI et al. Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. 2011 Funct. Integr. Genomics pmid:21538138
Gasiorowski K et al. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? 2011 CNS Neurol Disord Drug Targets pmid:21222632
Zeng H et al. The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. 2011 J Ethnopharmacol pmid:21466840
Xie S et al. Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. 2011 J. Pharm. Pharmacol. pmid:21235595
Chen FP et al. Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002. 2011 Evid Based Complement Alternat Med pmid:19339485
Enomoto R et al. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. 2011 Cancer Chemother. Pharmacol. pmid:20658136
Calvo TR et al. Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. 2011 Evid Based Complement Alternat Med pmid:19696193
Chen SS et al. Polyphenols inhibit indoleamine 3,5-dioxygenase-1 enzymatic activity--a role of immunomodulation in chemoprevention. 2012 Discov Med pmid:23200064
Chen SS et al. Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. 2012 Discov Med pmid:22284780
Li X et al. Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. 2012 Evid Based Complement Alternat Med pmid:22235229
Li WJ et al. Phenolic compounds and antioxidant activities of Liriope muscari. 2012 Molecules pmid:22328078
Matsunaga T et al. Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. 2012 Front Pharmacol pmid:22319498
Eylenstein A et al. Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions. 2012 J. Biol. Chem. pmid:22110130
Chi DS et al. Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway. 2012 Clin Mol Allergy pmid:22309647
Zhang N et al. A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model. 2012 Evid Based Complement Alternat Med pmid:22272213