Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

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Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Acute Lung Injury D055371 33 associated lipids
Papillomavirus Infections D030361 4 associated lipids
Neurodegenerative Diseases D019636 32 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Myocardial Reperfusion Injury D015428 20 associated lipids
Translocation, Genetic D014178 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Penile Induration D010411 4 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Huan SK et al. Scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression. 2012 Molecules pmid:22634839
Wilczańska-Barska A et al. Enhanced accumulation of secondary metabolites in hairy root cultures of Scutellaria lateriflora following elicitation. 2012 Biotechnol. Lett. pmid:22639092
He F et al. Wogonin potentiates cisplatin-induced cancer cell apoptosis through accumulation of intracellular reactive oxygen species. 2012 Oncol. Rep. pmid:22665077
Chow SE et al. Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. 2012 J. Cell. Biochem. pmid:22689083
Wang TC et al. Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest. 2012 Evid Based Complement Alternat Med pmid:22693529
Vauzour D Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. 2012 Oxid Med Cell Longev pmid:22701758
Tong L et al. Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry. 2012 J Pharm Biomed Anal pmid:22703838
Oshima N et al. Quantitative analysis of anti-inflammatory activity of orengedokuto: importance of combination of flavonoids in inhibition of PGE2 production in mouse macrophage-like cell line J774.1. 2013 J Nat Med pmid:22729955
Cheng J et al. Effect of magnetic nanoparticles of Fe3O4 and wogonin on the reversal of multidrug resistance in K562/A02 cell line. 2012 Int J Nanomedicine pmid:22745547
Lee DH et al. Wogonin induces apoptosis by activating the AMPK and p53 signaling pathways in human glioblastoma cells. 2012 Cell. Signal. pmid:22846543
Kim SG et al. Development of simultaneous analysis for marker constituents in Hwangryunhaedok-tang () and its application in commercial herbal formulas. 2013 J Nat Med pmid:22855402
Zhu Y et al. Simultaneous determination of active flavonoids and alkaloids of Tang-Min-Ling-Pill in rat plasma by liquid chromatography tandem mass spectrometry. 2012 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22883103
Chen H et al. A new strategy for quality control and qualitative analysis of Yinhuang preparations by HPLC-DAD-MS/MS. 2012 Anal Bioanal Chem pmid:22885972
Xia Y et al. A novel process related impurity and forced degradation study of synthetic wogonin: development of a liquid chromatographic method for purity control. 2012 J Pharm Biomed Anal pmid:22906689
Hayasaka S et al. Traditional Japanese herbal (kampo) medicines and treatment of ocular diseases: a review. 2012 Am. J. Chin. Med. pmid:22928823
Tsai CF et al. Wogonin induces reactive oxygen species production and cell apoptosis in human glioma cancer cells. 2012 Int J Mol Sci pmid:22949836
Im AR et al. Scutellaria baicalensis Extracts and Flavonoids Protect Rat L6 Cells from Antimycin A-Induced Mitochondrial Dysfunction. 2012 Evid Based Complement Alternat Med pmid:22969827
Kim SJ et al. Antitumor actions of baicalein and wogonin in HT-29 human colorectal cancer cells. 2012 Mol Med Rep pmid:22992837
Xia B et al. A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. 2012 Mol. Pharm. pmid:23033922
Chen S et al. Natural inhibitors of indoleamine 3,5-dioxygenase induced by interferon-gamma in human neural stem cells. 2012 Biochem. Biophys. Res. Commun. pmid:23063682