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Wogonin induces apoptosis in RPMI 8226, a human myeloma cell line, by downregulating phospho-Akt and overexpressing Bax. |
2013 |
Life Sci. |
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Polyphenols inhibit indoleamine 3,5-dioxygenase-1 enzymatic activity--a role of immunomodulation in chemoprevention. |
2012 |
Discov Med |
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Kimura Y and Sumiyoshi M |
Anti-tumor and anti-metastatic actions of wogonin isolated from Scutellaria baicalensis roots through anti-lymphangiogenesis. |
2013 |
Phytomedicine |
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Wang F et al. |
Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. |
2013 |
Toxicology |
pmid:23246481
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Yang Y et al. |
Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. |
2012 |
PLoS ONE |
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Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway. |
2013 |
Int. J. Oncol. |
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Yeh CH et al. |
Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells. |
2014 |
Environ. Toxicol. |
pmid:23362215
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Yang L et al. |
Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins. |
2013 |
Apoptosis |
pmid:23371323
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Inhibition of TNF-α-induced MUC5AC mucin gene expression and production by wogonin through the inactivation of NF-κB signaling in airway epithelial cells. |
2014 |
Phytother Res |
pmid:23463646
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Yeh CH et al. |
Protective effect of wogonin on proinflammatory cytokine generation via Jak1/3-STAT1/3 pathway in lipopolysaccharide stimulated BV2 microglial cells. |
2015 |
Toxicol Ind Health |
pmid:23592745
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Bak EJ et al. |
Wogonin ameliorates hyperglycemia and dyslipidemia via PPARα activation in db/db mice. |
2014 |
Clin Nutr |
pmid:23623334
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Song X et al. |
Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein. |
2013 |
Toxicol. Appl. Pharmacol. |
pmid:23707765
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Yu C et al. |
Different extraction pretreatments significantly change the flavonoid contents of Scutellaria baicalensis. |
2013 |
Pharm Biol |
pmid:23738852
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Wang H et al. |
Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway. |
2014 |
Mol. Carcinog. |
pmid:23761018
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Kim TW et al. |
Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity. |
2013 |
Planta Med. |
pmid:23818268
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Zhang Y et al. |
V8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma. |
2014 |
Arch. Toxicol. |
pmid:23835921
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Zhao L et al. |
Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway. |
2013 |
Biochem. Cell Biol. |
pmid:23859016
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Attia SM et al. |
Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. |
2013 |
Food Chem. Toxicol. |
pmid:23872129
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Wang Y et al. |
GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. |
2013 |
Toxicol. Lett. |
pmid:23872260
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He L et al. |
Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. |
2013 |
Toxicology |
pmid:23907061
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