| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Lung Injury | D055371 | 33 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yu JS and Kim AK | Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. | 2011 | Mol. Cells | pmid:21448585 |
| Fong SYK et al. | Brain Uptake of Bioactive Flavones in Scutellariae Radix and Its Relationship to Anxiolytic Effect in Mice. | 2017 | Mol. Pharm. | pmid:28426226 |
| Xia B et al. | A novel local recycling mechanism that enhances enteric bioavailability of flavonoids and prolongs their residence time in the gut. | 2012 | Mol. Pharm. | pmid:23033922 |
| Chang YL et al. | Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. | 2001 | Mol. Pharmacol. | pmid:11502881 |
| Hong M et al. | Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. | 2018 | Molecules | pmid:29439451 |
| Sun C et al. | Rapid Isolation and Determination of Flavones in Biological Samples Using Zinc Complexation Coupled with High-Performance Liquid Chromatography. | 2016 | Molecules | pmid:27537870 |
| Shin HS et al. | Skullcap (Scutellaria baicalensis) extract and its active compound, wogonin, inhibit ovalbumin-induced Th2-mediated response. | 2014 | Molecules | pmid:24566319 |
| Huan SK et al. | Scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression. | 2012 | Molecules | pmid:22634839 |
| Li WJ et al. | Phenolic compounds and antioxidant activities of Liriope muscari. | 2012 | Molecules | pmid:22328078 |
| Lee JY and Park W | Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid. | 2015 | Molecules | pmid:25913928 |
| Talbi A et al. | Pharmacokinetics, tissue distribution, excretion and plasma protein binding studies of wogonin in rats. | 2014 | Molecules | pmid:24786691 |
| Woźniak D et al. | Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. | 2004 | Nahrung | pmid:15053344 |
| Woźniak D et al. | Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix. | 2015 | Nat. Prod. Res. | pmid:25427178 |
| Islam MN et al. | A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae radix extract. | 2012 | Nat. Prod. Res. | pmid:22304335 |
| Cao XD et al. | Antitumor constituents from the leaves of Carya cathayensis. | 2012 | Nat. Prod. Res. | pmid:22007794 |
| Zhu Y and Wang J | Wogonin increases β-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimer's disease. | 2015 | Neurol. Sci. | pmid:25596147 |
| Ha SK et al. | 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. | 2012 | Neuropharmacology | pmid:22465818 |
| Kim H et al. | The plant flavonoid wogonin suppresses death of activated C6 rat glial cells by inhibiting nitric oxide production. | 2001 | Neurosci. Lett. | pmid:11489548 |
| Shen SC et al. | Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids. | 2006 | Neuroscience | pmid:16580779 |
| Hardeland R and Pandi-Perumal SR | Melatonin, a potent agent in antioxidative defense: actions as a natural food constituent, gastrointestinal factor, drug and prodrug. | 2005 | Nutr Metab (Lond) | pmid:16153306 |