| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acute Lung Injury | D055371 | 33 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
| Neurodegenerative Diseases | D019636 | 32 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Penile Induration | D010411 | 4 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yang Y et al. | Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. | 2012 | PLoS ONE | pmid:23251389 |
| Zhu J et al. | Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis. | 2012 | PLoS ONE | pmid:22590504 |
| Kim JO et al. | Phorbol ester or epidermal growth-factor-induced MUC5AC mucin gene expression and production from airway epithelial cells are inhibited by apigenin and wogonin. | 2012 | Phytother Res | pmid:22388989 |
| Li Y and Martin RC | Herbal medicine and hepatocellular carcinoma: applications and challenges. | 2011 | Evid Based Complement Alternat Med | pmid:21799681 |
| Kim EJ et al. | Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. | 2011 | Acta Physiol (Oxf) | pmid:21306568 |
| Shia CS et al. | Metabolism and pharmacokinetics of san-huang-xie-xin-tang, a polyphenol-rich chinese medicine formula, in rats and ex-vivo antioxidant activity. | 2011 | Evid Based Complement Alternat Med | pmid:19737807 |
| Chen CM et al. | Maternal baicalin treatment increases fetal lung surfactant phospholipids in rats. | 2011 | Evid Based Complement Alternat Med | pmid:19584080 |
| Shih YT et al. | San-Huang-Xie-Xin-Tang Protects against Activated Microglia- and 6-OHDA-Induced Toxicity in Neuronal SH-SY5Y Cells. | 2011 | Evid Based Complement Alternat Med | pmid:19339484 |
| Liu YM et al. | Wogonin ameliorates lipotoxicity-induced apoptosis of cultured vascular smooth muscle cells via interfering with DAG-PKC pathway. | 2011 | Acta Pharmacol. Sin. | pmid:21986573 |
| Shi R et al. | Simultaneous determination of five flavonoids from Scutellaria Barbata extract in rat plasma by LC-MS/MS and its application to pharmacokinetic study. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21514902 |
| Chen S et al. | Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells: sensitivity of ovarian cancer cells to phyto-active chemicals. | 2011 | Cell Biol. Toxicol. | pmid:20872277 |
| Li C et al. | Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. | 2011 | J Pharm Biomed Anal | pmid:21051171 |
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| Ahn SH et al. | Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. | 2011 | BMC Neurosci | pmid:21810275 |
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| Kimura Y and Sumiyoshi M | Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. | 2011 | Eur. J. Pharmacol. | pmid:21549115 |
| Takahashi H et al. | Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. | 2011 | Biochim. Biophys. Acta | pmid:21596068 |
| Yang DZ et al. | Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. | 2011 | Talanta | pmid:21726714 |
| Li T et al. | Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. | 2011 | Eur J Drug Metab Pharmacokinet | pmid:21713461 |
| Lee YM et al. | Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats. | 2011 | J. Cardiovasc. Pharmacol. | pmid:21436723 |
| Yu JS and Kim AK | Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. | 2011 | Mol. Cells | pmid:21448585 |
| Zhao L et al. | Developmental toxicity and genotoxicity studies of wogonin. | 2011 | Regul. Toxicol. Pharmacol. | pmid:21459121 |
| Chen P et al. | Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. | 2011 | Toxicology | pmid:21295103 |
| Yang L et al. | Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. | 2011 | Cancer Sci. | pmid:21244577 |
| Chow SE et al. | Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. | 2011 | Cancer Chemother. Pharmacol. | pmid:21207227 |
| Chen CY et al. | Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. | 2011 | J. Nutr. Biochem. | pmid:21190831 |
| Lin CC et al. | Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. | 2011 | Int. J. Oncol. | pmid:21573491 |
| Messaoudene D et al. | Ex vivo effects of flavonoïds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behçet's disease. | 2011 | J Inflamm (Lond) | pmid:22104639 |
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| Enomoto R et al. | Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. | 2011 | Cancer Chemother. Pharmacol. | pmid:20658136 |
| Calvo TR et al. | Mutagenic Activity of Indigofera truxillensis and I. suffruticosa Aerial Parts. | 2011 | Evid Based Complement Alternat Med | pmid:19696193 |
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