Gao J et al. |
Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. |
2010 |
J Pharm Biomed Anal |
pmid:20457505
|
Lin CW et al. |
12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCalpha/ERK/NF-kappaB-dependent MMP-9 expression. |
2010 |
J. Cell. Physiol. |
pmid:20458747
|
Parajuli P et al. |
Delayed growth of glioma by Scutellaria flavonoids involve inhibition of Akt, GSK-3 and NF-κB signaling. |
2011 |
J. Neurooncol. |
pmid:20467782
|
Hung CW et al. |
Stem cell-based neuroprotective and neurorestorative strategies. |
2010 |
Int J Mol Sci |
pmid:20559500
|
Khoo BY et al. |
Apoptotic effects of chrysin in human cancer cell lines. |
2010 |
Int J Mol Sci |
pmid:20559509
|
Zhao Q et al. |
Wogonin potentiates the antitumor effects of low dose 5-fluorouracil against gastric cancer through induction of apoptosis by down-regulation of NF-kappaB and regulation of its metabolism. |
2010 |
Toxicol. Lett. |
pmid:20570612
|
Enomoto R et al. |
Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. |
2011 |
Cancer Chemother. Pharmacol. |
pmid:20658136
|
Xu H et al. |
Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. |
2010 |
Bioresour. Technol. |
pmid:20708926
|
Tilton R et al. |
A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906. |
2010 |
Chin Med |
pmid:20727161
|
Chen S et al. |
Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells: sensitivity of ovarian cancer cells to phyto-active chemicals. |
2011 |
Cell Biol. Toxicol. |
pmid:20872277
|
Zan B et al. |
Simultaneous quantification of multiple active components from Xiexin decoction in rat plasma by LC-ESI-MS/MS: application in pharmacokinetics. |
2011 |
Biomed. Chromatogr. |
pmid:20872909
|
Lim JS et al. |
Wogonin induces differentiation and neurite outgrowth of neural precursor cells. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20888794
|
Hou YC et al. |
Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats. |
2011 |
Planta Med. |
pmid:20957598
|
Meng X et al. |
Effects of Various Flavonoids on the α-Synuclein Fibrillation Process. |
2010 |
Parkinsons Dis |
pmid:20976092
|
Li C et al. |
Identification and quantification of baicalein, wogonin, oroxylin A and their major glucuronide conjugated metabolites in rat plasma after oral administration of Radix scutellariae product. |
2011 |
J Pharm Biomed Anal |
pmid:21051171
|
Wei L et al. |
Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. |
2010 |
J. Cell. Biochem. |
pmid:21053277
|
Jeong HJ et al. |
Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism. |
2010 |
J Neuroinflammation |
pmid:21108840
|
Kunwar RM et al. |
Traditional herbal medicine in far-west Nepal: a pharmacological appraisal. |
2010 |
J Ethnobiol Ethnomed |
pmid:21144003
|
Chen J et al. |
Simultaneous quantification of twelve active components in Yiqing granule by ultra-performance liquid chromatography: application to quality control study. |
2011 |
Biomed. Chromatogr. |
pmid:21154891
|
Ye G et al. |
Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. |
2010 |
Chem. Biodivers. |
pmid:21162005
|
Katrahalli U et al. |
Interaction of bioactive coomassie brilliant blue g with protein: insights from spectroscopic methods. |
2010 Oct-Dec |
Sci Pharm |
pmid:21179322
|
Chen CY et al. |
Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages. |
2011 |
J. Nutr. Biochem. |
pmid:21190831
|
Chow SE et al. |
Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. |
2011 |
Cancer Chemother. Pharmacol. |
pmid:21207227
|
Gasiorowski K et al. |
Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration? |
2011 |
CNS Neurol Disord Drug Targets |
pmid:21222632
|
Xie S et al. |
Structure-metabolism relationships for the glucuronidation of flavonoids by UGT1A3 and UGT1A9. |
2011 |
J. Pharm. Pharmacol. |
pmid:21235595
|
Yang L et al. |
Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. |
2011 |
Cancer Sci. |
pmid:21244577
|
Chen P et al. |
Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. |
2011 |
Toxicology |
pmid:21295103
|
Kim EJ et al. |
Baicalein and wogonin are activators of rat TREK-2 two-pore domain K+ channel. |
2011 |
Acta Physiol (Oxf) |
pmid:21306568
|
Mazzio EA et al. |
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. |
2011 |
Int J Mol Sci |
pmid:21340000
|
Tang H et al. |
The scavenging of superoxide radicals promotes apoptosis induced by a novel cell-permeable fusion protein, sTRAIL:FeSOD, in tumor necrosis factor-related apoptosis-inducing ligand-resistant leukemia cells. |
2011 |
BMC Biol. |
pmid:21418589
|
Lee YM et al. |
Wogonin suppresses arrhythmias, inflammatory responses, and apoptosis induced by myocardial ischemia/reperfusion in rats. |
2011 |
J. Cardiovasc. Pharmacol. |
pmid:21436723
|
Yu JS and Kim AK |
Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells. |
2011 |
Mol. Cells |
pmid:21448585
|
Gao J et al. |
The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. |
2011 |
Toxicol. Appl. Pharmacol. |
pmid:21457722
|
Zhao L et al. |
Developmental toxicity and genotoxicity studies of wogonin. |
2011 |
Regul. Toxicol. Pharmacol. |
pmid:21459121
|
Zeng H et al. |
The inhibitory activities of the components of Huang-Lian-Jie-Du-Tang (HLJDT) on eicosanoid generation via lipoxygenase pathway. |
2011 |
J Ethnopharmacol |
pmid:21466840
|
Jeong JC et al. |
Silibinin induces apoptosis via calpain-dependent AIF nuclear translocation in U87MG human glioma cell death. |
2011 |
J. Exp. Clin. Cancer Res. |
pmid:21501525
|
Shi R et al. |
Simultaneous determination of five flavonoids from Scutellaria Barbata extract in rat plasma by LC-MS/MS and its application to pharmacokinetic study. |
2011 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:21514902
|
Park NI et al. |
Enhancement of flavone levels through overexpression of chalcone isomerase in hairy root cultures of Scutellaria baicalensis. |
2011 |
Funct. Integr. Genomics |
pmid:21538138
|
Kimura Y and Sumiyoshi M |
Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. |
2011 |
Eur. J. Pharmacol. |
pmid:21549115
|
Lin CC et al. |
Wogonin triggers apoptosis in human osteosarcoma U-2 OS cells through the endoplasmic reticulum stress, mitochondrial dysfunction and caspase-3-dependent signaling pathways. |
2011 |
Int. J. Oncol. |
pmid:21573491
|
Takahashi H et al. |
Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. |
2011 |
Biochim. Biophys. Acta |
pmid:21596068
|
Lim H et al. |
Effects of flavonoids on matrix metalloproteinase-13 expression of interleukin-1β-treated articular chondrocytes and their cellular mechanisms: inhibition of c-Fos/AP-1 and JAK/STAT signaling pathways. |
2011 |
J. Pharmacol. Sci. |
pmid:21606625
|
Lei W et al. |
Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. |
2010 |
Genet. Mol. Biol. |
pmid:21637484
|
Li T et al. |
Inhibitory effects of wogonin on catalytic activity of cytochrome P450 enzyme in human liver microsomes. |
2011 |
Eur J Drug Metab Pharmacokinet |
pmid:21713461
|
Yang DZ et al. |
Development of a novel method combining HPLC fingerprint and multi-ingredients quantitative analysis for quality evaluation of traditional Chinese medicine preparation. |
2011 |
Talanta |
pmid:21726714
|
Su SY and Hsieh CL |
Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. |
2011 |
Chin Med |
pmid:21740583
|
Polier G et al. |
Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1. |
2011 |
Cell Death Dis |
pmid:21776020
|
Tan W et al. |
Anti-cancer natural products isolated from chinese medicinal herbs. |
2011 |
Chin Med |
pmid:21777476
|
Yang C et al. |
Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway. |
2011 |
PLoS ONE |
pmid:21779360
|
Han S et al. |
Herbal extract THI improves metabolic abnormality in mice fed a high-fat diet. |
2011 |
Nutr Res Pract |
pmid:21779522
|