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Wogonin inhibits H2O2-induced vascular permeability through suppressing the phosphorylation of caveolin-1. |
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Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. |
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Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway. |
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Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells. |
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Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins. |
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Protective effect of wogonin on proinflammatory cytokine generation via Jak1/3-STAT1/3 pathway in lipopolysaccharide stimulated BV2 microglial cells. |
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Wogonin ameliorates hyperglycemia and dyslipidemia via PPARα activation in db/db mice. |
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Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein. |
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Pharm Biol |
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Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway. |
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Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity. |
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Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. |
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GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. |
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Wogonin induced G1 cell cycle arrest by regulating Wnt/β-catenin signaling pathway and inactivating CDK8 in human colorectal cancer carcinoma cells. |
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Toxicology |
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Wogonin induces apoptosis by suppressing E6 and E7 expressions and activating intrinsic signaling pathways in HPV-16 cervical cancer cells. |
2013 |
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Toxicology |
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The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters. |
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J Pharm Sci |
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Flavonoids from the leaves of Carya cathayensis Sarg. inhibit vascular endothelial growth factor-induced angiogenesis. |
2014 |
Fitoterapia |
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Influence of mefenamic acid on the intestinal absorption and metabolism of three bioactive flavones in Radix Scutellariae and potential pharmacological impact. |
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Pharm Biol |
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Wogonin influences vascular permeability via Wnt/β-catenin pathway. |
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Species difference in the inhibitory potentials of non-steroidal anti-inflammatory drugs on the hepatic sulfation and glucuronidation of bioactive flavonoids: differential observations among common inhibition parameters. |
2014 |
Xenobiotica |
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A wogonin-loaded glycyrrhetinic acid-modified liposome for hepatic targeting with anti-tumor effects. |
2014 |
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Probe substrate and enzyme source-dependent inhibition of UDP-glucuronosyltransferase (UGT) 1A9 by wogonin. |
2013 |
Afr Health Sci |
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Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549. |
2013 |
PLoS ONE |
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