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Wogonin, a natural and biologically-active flavonoid, influences a murine WEHI-3 leukemia model in vivo through enhancing populations of T- and B-cells. |
2013 Nov-Dec |
In Vivo |
pmid:24292576
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Liu J et al. |
Screening of osteoanagenesis-active compounds from Scutellaria baicalensis Georgi by hPDLC/CMC-online-HPLC/MS. |
2014 |
Fitoterapia |
pmid:24393619
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Zhou YQ et al. |
[Recombinant soluble CD40 ligand enhances Wogonin-induced antitumor activity]. |
2013 |
Sichuan Da Xue Xue Bao Yi Xue Ban |
pmid:24490490
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Zhou M et al. |
Wogonin inhibits H2O2-induced angiogenesis via suppressing PI3K/Akt/NF-κB signaling pathway. |
2014 |
Vascul. Pharmacol. |
pmid:24534483
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Zhang F and Wang G |
A review of non-nucleoside anti-hepatitis B virus agents. |
2014 |
Eur J Med Chem |
pmid:24549242
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Shin HS et al. |
Skullcap (Scutellaria baicalensis) extract and its active compound, wogonin, inhibit ovalbumin-induced Th2-mediated response. |
2014 |
Molecules |
pmid:24566319
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Gong WY et al. |
Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro. |
2014 |
Int. J. Oncol. |
pmid:24604573
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Qian C et al. |
Wogonin-enhanced reactive oxygen species-induced apoptosis and potentiated cytotoxic effects of chemotherapeutic agents by suppression Nrf2-mediated signaling in HepG2 cells. |
2014 |
Free Radic. Res. |
pmid:24666416
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Yao J et al. |
Wogonin prevents lipopolysaccharide-induced acute lung injury and inflammation in mice via peroxisome proliferator-activated receptor gamma-mediated attenuation of the nuclear factor-kappaB pathway. |
2014 |
Immunology |
pmid:24766487
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Talbi A et al. |
Pharmacokinetics, tissue distribution, excretion and plasma protein binding studies of wogonin in rats. |
2014 |
Molecules |
pmid:24786691
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Fong SY et al. |
Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies. |
2014 |
J Pharm Biomed Anal |
pmid:24803030
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Zhao K et al. |
Wogonin inhibits LPS-induced tumor angiogenesis via suppressing PI3K/Akt/NF-κB signaling. |
2014 |
Eur. J. Pharmacol. |
pmid:24858369
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Polier G et al. |
Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263. |
2015 |
Int. J. Cancer |
pmid:24895203
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Yao J et al. |
NF-κB and Nrf2 signaling pathways contribute to wogonin-mediated inhibition of inflammation-associated colorectal carcinogenesis. |
2014 |
Cell Death Dis |
pmid:24901054
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Zhao Y et al. |
Wogonin suppresses human alveolar adenocarcinoma cell A549 migration in inflammatory microenvironment by modulating the IL-6/STAT3 signaling pathway. |
2015 |
Mol. Carcinog. |
pmid:24976450
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Ku SK and Bae JS |
Antithrombotic activities of wogonin and wogonoside via inhibiting platelet aggregation. |
2014 |
Fitoterapia |
pmid:25020199
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Nam KW et al. |
The role of wogonin in controlling SOCS3 expression in neuronal cells. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:25035930
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Huang KF et al. |
[Experimental study on inhibitory effect of wogonin on proliferation and invasion of breast cancer cells]. |
2014 |
Zhongguo Zhong Yao Za Zhi |
pmid:25039187
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Yang H et al. |
Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells. |
2014 |
Oncotarget |
pmid:25149543
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Hosseinzadeh Z et al. |
Effect of TGFβ on Na+/K+ ATPase activity in megakaryocytes. |
2014 |
Biochem. Biophys. Res. Commun. |
pmid:25168590
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Zhao K et al. |
Wogonin suppresses melanoma cell B16-F10 invasion and migration by inhibiting Ras-medicated pathways. |
2014 |
PLoS ONE |
pmid:25203554
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Kwak S et al. |
Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo. |
2014 |
Toxicol. Appl. Pharmacol. |
pmid:25223693
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Marsh Z et al. |
Effect of light, methyl jasmonate and cyclodextrin on production of phenolic compounds in hairy root cultures of Scutellaria lateriflora. |
2014 |
Phytochemistry |
pmid:25236693
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Lee W et al. |
Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo. |
2015 |
Inflammation |
pmid:25249339
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Xu X et al. |
Wogonin reverses multi-drug resistance of human myelogenous leukemia K562/A02 cells via downregulation of MRP1 expression by inhibiting Nrf2/ARE signaling pathway. |
2014 |
Biochem. Pharmacol. |
pmid:25264278
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Xiao JR et al. |
Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders. |
2014 |
J Ocul Pharmacol Ther |
pmid:25280175
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Xu S et al. |
Wogonin prevents rat dorsal root ganglion neurons death via inhibiting tunicamycin-induced ER stress in vitro. |
2015 |
Cell. Mol. Neurobiol. |
pmid:25381475
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Aslan E and Adem S |
In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
pmid:25388478
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Chen F et al. |
Wogonin protects rat dorsal root ganglion neurons against tunicamycin-induced ER stress through the PERK-eIF2α-ATF4 signaling pathway. |
2015 |
J. Mol. Neurosci. |
pmid:25417142
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Woźniak D et al. |
Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix. |
2015 |
Nat. Prod. Res. |
pmid:25427178
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Yan T et al. |
Wogonin modulates hydroperoxide-induced apoptosis via PI3K/Akt pathway in retinal pigment epithelium cells. |
2014 |
Diagn Pathol |
pmid:25432585
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Chen S et al. |
Wogonin inhibits LPS-induced inflammatory responses in rat dorsal root ganglion neurons via inhibiting TLR4-MyD88-TAK1-mediated NF-κB and MAPK signaling pathway. |
2015 |
Cell. Mol. Neurobiol. |
pmid:25504431
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Boozari M et al. |
Growth inhibition and apoptosis induction by Scutellaria pinnatifida A. Ham. on HL-60 and K562 leukemic cell lines. |
2015 |
Environ. Toxicol. Pharmacol. |
pmid:25546119
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Ku SK et al. |
Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2. |
2015 |
Arch. Pharm. Res. |
pmid:25564337
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Zhu Y and Wang J |
Wogonin increases β-amyloid clearance and inhibits tau phosphorylation via inhibition of mammalian target of rapamycin: potential drug to treat Alzheimer's disease. |
2015 |
Neurol. Sci. |
pmid:25596147
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Lucas CD et al. |
Wogonin induces eosinophil apoptosis and attenuates allergic airway inflammation. |
2015 |
Am. J. Respir. Crit. Care Med. |
pmid:25629436
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Tan CX et al. |
Activities of wogonin analogs and other flavones against Flavobacterium columnare. |
2015 |
Chem. Biodivers. |
pmid:25676507
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Dong LL et al. |
An enhanced preparation and purification of the major antioxidants baicalein and wogonin from Scutellariae radix. |
2012 |
Food Chem |
pmid:25683416
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Ku SK and Bae JS |
Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. |
2015 |
BMB Rep |
pmid:25739393
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Ge W et al. |
Wogonin Induced Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Human Malignant Neuroblastoma Cells Via IRE1α-Dependent Pathway. |
2015 |
J. Mol. Neurosci. |
pmid:25740014
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Persson C |
Drug-induced death of eosinophils. Promises and pitfalls. |
2015 |
Am. J. Respir. Crit. Care Med. |
pmid:25767918
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Hu C et al. |
Wogonin induces apoptosis and endoplasmic reticulum stress in HL-60 leukemia cells through inhibition of the PI3K-AKT signaling pathway. |
2015 |
Oncol. Rep. |
pmid:25846394
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Lee JY and Park W |
Anti-Inflammatory Effect of Wogonin on RAW 264.7 Mouse Macrophages Induced with Polyinosinic-Polycytidylic Acid. |
2015 |
Molecules |
pmid:25913928
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Wang W et al. |
Wogonin suppresses inflammatory response and maintains intestinal barrier function via TLR4-MyD88-TAK1-mediated NF-κB pathway in vitro. |
2015 |
Inflamm. Res. |
pmid:25917044
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Zhao L et al. |
LW-213 induces G2/M cell cycle arrest through AKT/GSK3β/β-catenin signaling pathway in human breast cancer cells. |
2016 |
Mol. Carcinog. |
pmid:25945460
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Huang Y et al. |
Wogonin inhibits LPS-induced vascular permeability via suppressing MLCK/MLC pathway. |
2015 |
Vascul. Pharmacol. |
pmid:25956732
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Xiao W et al. |
Wogonin Inhibits Tumor-derived Regulatory Molecules by Suppressing STAT3 Signaling to Promote Tumor Immunity. |
2015 |
J. Immunother. |
pmid:25962106
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Zhang YM et al. |
Wogonin suppresses osteopontin expression in adipocytes by activating PPARα. |
2015 |
Acta Pharmacol. Sin. |
pmid:26073326
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Sun HL et al. |
Endotoxin-induced acute lung injury in mice is protected by 5,7-dihydroxy-8-methoxyflavone via inhibition of oxidative stress and HIF-1α. |
2016 |
Environ. Toxicol. |
pmid:26213241
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Liu J et al. |
Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression. |
2015 |
PLoS ONE |
pmid:26317778
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