| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma | D002277 | 18 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Lymphoma, Large B-Cell, Diffuse | D016403 | 13 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Myocardial Reperfusion Injury | D015428 | 20 associated lipids |
| Translocation, Genetic | D014178 | 20 associated lipids |
| Papillomavirus Infections | D030361 | 4 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pan SY et al. | New perspectives on chinese herbal medicine (zhong-yao) research and development. | 2011 | Evid Based Complement Alternat Med | pmid:21785622 |
| Qi XF et al. | Bambusae caulis in Liquamen Suppresses the Expression of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine in Human Keratinocytes due to Antioxidant Effect. | 2012 | Evid Based Complement Alternat Med | pmid:21785648 |
| Li Y and Martin RC | Herbal medicine and hepatocellular carcinoma: applications and challenges. | 2011 | Evid Based Complement Alternat Med | pmid:21799681 |
| Samarghandian S et al. | Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3. | 2011 | Clinics (Sao Paulo) | pmid:21808878 |
| Ahn SH et al. | Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons. | 2011 | BMC Neurosci | pmid:21810275 |
| Dong P et al. | Wogonin, an active ingredient of Chinese herb medicine Scutellaria baicalensis, inhibits the mobility and invasion of human gallbladder carcinoma GBC-SD cells by inducing the expression of maspin. | 2011 | J Ethnopharmacol | pmid:21855619 |
| Chen CY et al. | Comparative chemical and statistical analysis of cultivated and wild Radix Scutellariae. | 2011 | Am. J. Chin. Med. | pmid:21905290 |
| Li C et al. | Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones. | 2011 | Biopharm Drug Dispos | pmid:21928297 |
| Lee MY et al. | A 4-week Repeated Dose Oral Toxicity and Cytotoxicity Study of Gumiganghwaltang in Crl:CD (SD) Rats. | 2011 | Toxicol Int | pmid:21976821 |
| Liu YM et al. | Wogonin ameliorates lipotoxicity-induced apoptosis of cultured vascular smooth muscle cells via interfering with DAG-PKC pathway. | 2011 | Acta Pharmacol. Sin. | pmid:21986573 |
| Cao XD et al. | Antitumor constituents from the leaves of Carya cathayensis. | 2012 | Nat. Prod. Res. | pmid:22007794 |
| Dandawate S et al. | Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-β1 activity. | 2012 | Cancer Immunol. Immunother. | pmid:22057676 |
| Petraglia AL et al. | Stuck at the bench: Potential natural neuroprotective compounds for concussion. | 2011 | Surg Neurol Int | pmid:22059141 |
| Schrader KK | Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus). | 2010 | Toxins (Basel) | pmid:22069655 |
| Lin B | Polyphenols and neuroprotection against ischemia and neurodegeneration. | 2011 | Mini Rev Med Chem | pmid:22070681 |
| Ding J et al. | Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression. | 2012 | J. Biol. Chem. | pmid:22086925 |
| Messaoudene D et al. | Ex vivo effects of flavonoïds extracted from Artemisia herba alba on cytokines and nitric oxide production in Algerian patients with Adamantiades-Behçet's disease. | 2011 | J Inflamm (Lond) | pmid:22104639 |
| Eylenstein A et al. | Transcription factor NF-κB regulates expression of pore-forming Ca2+ channel unit, Orai1, and its activator, STIM1, to control Ca2+ entry and affect cellular functions. | 2012 | J. Biol. Chem. | pmid:22110130 |
| Lu QY et al. | Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts. | 2012 | Pancreas | pmid:22158070 |
| Li C et al. | Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae. | 2012 | AAPS J | pmid:22167378 |
| Huang KF et al. | Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway. | 2012 | Int. Immunopharmacol. | pmid:22182776 |
| Li J et al. | Studying on inclusion complexes of Wogonin with β-cyclodextrin and hydroxypropyl-cyclodextrin. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22192416 |
| Wu B et al. | Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells. | 2011 | BMC Cancer | pmid:22204275 |
| Shao YX et al. | The molecular basis for the inhibition of human cytochrome P450 1A2 by oroxylin and wogonin. | 2012 | Eur. Biophys. J. | pmid:22228220 |
| Li X et al. | Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle. | 2012 | Evid Based Complement Alternat Med | pmid:22235229 |
| He H et al. | Screening active compounds acting on the epidermal growth factor receptor from Radix scutellariae via cell membrane chromatography online coupled with HPLC/MS. | 2012 | J Pharm Biomed Anal | pmid:22260968 |
| Zhang N et al. | A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model. | 2012 | Evid Based Complement Alternat Med | pmid:22272213 |
| Chen CC et al. | Wogonin improves histological and functional outcomes, and reduces activation of TLR4/NF-κB signaling after experimental traumatic brain injury. | 2012 | PLoS ONE | pmid:22272328 |
| Chen SS et al. | Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. | 2012 | Discov Med | pmid:22284780 |
| Islam MN et al. | A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae radix extract. | 2012 | Nat. Prod. Res. | pmid:22304335 |
| Chi DS et al. | Enhanced effects of cigarette smoke extract on inflammatory cytokine expression in IL-1β-activated human mast cells were inhibited by Baicalein via regulation of the NF-κB pathway. | 2012 | Clin Mol Allergy | pmid:22309647 |
| Matsunaga T et al. | Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers. | 2012 | Front Pharmacol | pmid:22319498 |
| Li WJ et al. | Phenolic compounds and antioxidant activities of Liriope muscari. | 2012 | Molecules | pmid:22328078 |
| Wang L et al. | Effect of magnetic nanoparticles on apoptosis and cell cycle induced by wogonin in Raji cells. | 2012 | Int J Nanomedicine | pmid:22359456 |
| Pham TA et al. | Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22366656 |
| Toton E et al. | The tetramethoxyflavone zapotin selectively activates protein kinase C epsilon, leading to its down-modulation accompanied by Bcl-2, c-Jun and c-Fos decrease. | 2012 | Eur. J. Pharmacol. | pmid:22381066 |
| Kim JO et al. | Phorbol ester or epidermal growth-factor-induced MUC5AC mucin gene expression and production from airway epithelial cells are inhibited by apigenin and wogonin. | 2012 | Phytother Res | pmid:22388989 |
| Lin CM et al. | Functional role of wogonin in anti-angiogenesis. | 2012 | Am. J. Chin. Med. | pmid:22419433 |
| Ha SK et al. | 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. | 2012 | Neuropharmacology | pmid:22465818 |
| Shih HC and Yang LL | Relaxant effect induced by wogonin from Scutellaria baicalensis on rat isolated uterine smooth muscle. | 2012 | Pharm Biol | pmid:22471999 |
| Lo YC et al. | Neuroprotective Effects of San-Huang-Xie-Xin-Tang in the MPP(+)/MPTP Models of Parkinson's Disease In Vitro and In Vivo. | 2012 | Evid Based Complement Alternat Med | pmid:22474505 |
| Kang SH et al. | Icariside II induces apoptosis in U937 acute myeloid leukemia cells: role of inactivation of STAT3-related signaling. | 2012 | PLoS ONE | pmid:22493659 |
| Ma X et al. | [Wogonin inhibits IGF-1-stimulated cell growth and estrogen receptor α expression in breast adenocarcinoma cell and angiogenesis of chick chorioallantoic membrane]. | 2012 | Sheng Li Xue Bao | pmid:22513472 |
| Li HY et al. | Comparative study of the effect of baicalin and its natural analogs on neurons with oxygen and glucose deprivation involving innate immune reaction of TLR2/TNFα. | 2012 | J. Biomed. Biotechnol. | pmid:22536016 |
| Ho FM et al. | Anti-atherosclerotic action of Ger-Gen-Chyn-Lian-Tang and AMPK-dependent lipid lowering effect in hepatocytes. | 2012 | J Ethnopharmacol | pmid:22543166 |
| Li Y et al. | Screening of anti-cancer agent using zebrafish: comparison with the MTT assay. | 2012 | Biochem. Biophys. Res. Commun. | pmid:22560901 |
| Ci X et al. | Different effects of farrerol on an OVA-induced allergic asthma and LPS-induced acute lung injury. | 2012 | PLoS ONE | pmid:22563373 |
| Koppula S et al. | Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease. | 2012 | Mediators Inflamm. | pmid:22577256 |
| Zhu J et al. | Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis. | 2012 | PLoS ONE | pmid:22590504 |
| Zhong Y et al. | Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response. | 2013 | Mol. Carcinog. | pmid:22593043 |