| MeSH term | MeSH ID | Detail |
|---|---|---|
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma | D002277 | 18 associated lipids |
Wogonin
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.
Cross Reference
Introduction
To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Wogonin?
Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Wogonin
PubChem Associated disorders and diseases
What pathways are associated with Wogonin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Wogonin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Wogonin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Wogonin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Wogonin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Wogonin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhao Q et al. | Two CYP82D Enzymes Function as Flavone Hydroxylases in the Biosynthesis of Root-Specific 4'-Deoxyflavones in Scutellaria baicalensis. | 2018 | Mol Plant | pmid:28842248 |
| Hong M et al. | Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. | 2018 | Molecules | pmid:29439451 |
| Hong ZP et al. | Wogonin exacerbates the cytotoxic effect of oxaliplatin by inducing nitrosative stress and autophagy in human gastric cancer cells. | 2018 | Phytomedicine | pmid:29433678 |
| Shimizu T et al. | Synergistic effect of baicalein, wogonin and oroxylin A mixture: multistep inhibition of the NF-κB signalling pathway contributes to an anti-inflammatory effect of Scutellaria root flavonoids. | 2018 | J Nat Med | pmid:28921127 |
| Sukkar B et al. | Inhibition of Lithium Sensitive Orai1/ STIM1 Expression and Store Operated Ca2+ Entry in Chorea-Acanthocytosis Neurons by NF-κB Inhibitor Wogonin. | 2018 | Cell. Physiol. Biochem. | pmid:30453283 |
| Wang CZ et al. | Deglycosylation of wogonoside enhances its anticancer potential. | 2018 | J Cancer Res Ther | pmid:30249874 |
| Go JH et al. | Wogonin suppresses the LPS‑enhanced invasiveness of MDA‑MB‑231 breast cancer cells by inhibiting the 5‑LO/BLT2 cascade. | 2018 | Int. J. Mol. Med. | pmid:30015917 |
| Sabra SA et al. | Self-assembled amphiphilic zein-lactoferrin micelles for tumor targeted co-delivery of rapamycin and wogonin to breast cancer. | 2018 | Eur J Pharm Biopharm | pmid:29689288 |
| Xu PP et al. | Wogonin Inhibits Growth of Mantle Cell Lymphoma Cells through Nuclear Factor-κB Signaling Pathway. | 2018 | Chin. Med. J. | pmid:29451160 |
| Meng XM et al. | Wogonin protects against cisplatin-induced acute kidney injury by targeting RIPK1-mediated necroptosis. | 2018 | Lab. Invest. | pmid:29200200 |
| Zhao K et al. | LW-215, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. | 2018 | Gene | pmid:29196258 |
| Zhang Y et al. | The Influence of Compatibility of Rhubarb and Radix Scutellariae on the Pharmacokinetics of Anthraquinones and Flavonoids in Rat Plasma. | 2018 | Eur J Drug Metab Pharmacokinet | pmid:29134502 |
| Fong SYK et al. | Brain Uptake of Bioactive Flavones in Scutellariae Radix and Its Relationship to Anxiolytic Effect in Mice. | 2017 | Mol. Pharm. | pmid:28426226 |
| Yamashita Y et al. | Short-step syntheses of naturally occurring polyoxygenated aromatics based on site-selective transformation. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28345416 |
| Wang J et al. | Mediating macrophage immunity with wogonin in mice with vascular inflammation. | 2017 | Mol Med Rep | pmid:28983597 |
| Kapoor S | Protective effects of wogonin against disease progression in different hepatic pathological conditions. | 2017 | Int. Immunopharmacol. | pmid:28886583 |
| Li HD et al. | Wogonin attenuates inflammation by activating PPAR-γ in alcoholic liver disease. | 2017 | Int. Immunopharmacol. | pmid:28646664 |
| Xu X et al. | Wogonin reversed resistant human myelogenous leukemia cells via inhibiting Nrf2 signaling by Stat3/NF-κB inactivation. | 2017 | Sci Rep | pmid:28150717 |
| Chen M et al. | Simultaneous determination of wogonin, oroxylin a, schisandrin, paeoniflorin and emodin in rat serum by HPLC-MS/MS and application to pharmacokinetic studies. | 2017 | Biomed. Chromatogr. | pmid:28236316 |
| Khan NM et al. | A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1β-induced activation of AP-1 in human OA chondrocytes. | 2017 | Sci Rep | pmid:28256567 |
| Ruibin J et al. | Therapy Effects of Wogonin on Ovarian Cancer Cells. | 2017 | Biomed Res Int | pmid:29181409 |
| Paudel MK et al. | An overview and comparison of a recombinant antigen-binding fragment and an antigen-binding fragment from a monoclonal antibody against wogonin glucuronide. | 2017 | J Nat Med | pmid:28623444 |
| Chen J et al. | Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. | 2017 | Biomed. Pharmacother. | pmid:28486193 |
| Shu Q et al. | Wogonin induces retinal neuron-like differentiation of bone marrow stem cells by inhibiting Notch-1 signaling. | 2017 | Oncotarget | pmid:28415701 |
| Paudel MK et al. | The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide. | 2017 | J. Biotechnol. | pmid:28392422 |
| Wu X et al. | Wogonin as a targeted therapeutic agent for EBV (+) lymphoma cells involved in LMP1/NF-κB/miR-155/PU.1 pathway. | 2017 | BMC Cancer | pmid:28222771 |
| Yu H et al. | Enhancement of solubility and dissolution rate of baicalein, wogonin and oroxylin A extracted from Radix scutellariae. | 2017 | Int J Pharm | pmid:28642200 |
| Khan NM et al. | Wogonin, a natural flavonoid, intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes. | 2017 | Chem. Biol. Interact. | pmid:28688942 |
| Wei CY et al. | Protective effect of wogonin on endotoxin-induced acute lung injury via reduction of p38 MAPK and JNK phosphorylation. | 2017 | Environ. Toxicol. | pmid:26892447 |
| Huynh DL et al. | Wogonin suppresses stem cell-like traits of CD133 positive osteosarcoma cell via inhibiting matrix metallopeptidase-9 expression. | 2017 | BMC Complement Altern Med | pmid:28606135 |
| Kudo M et al. | Bifunctional effects of O-methylated flavones from Scutellaria baicalensis Georgi on melanocytes: Inhibition of melanin production and intracellular melanosome transport. | 2017 | PLoS ONE | pmid:28182699 |
| Yang T et al. | Wogonin enhances intracellular adiponectin levels and suppresses adiponectin secretion in 3T3-L1 adipocytes. | 2017 | Endocr. J. | pmid:27667474 |
| Liu RX et al. | Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis. | 2017 | Chin J Nat Med | pmid:28284428 |
| Wang J et al. | Discovery and synthesis of novel Wogonin derivatives with potent antitumor activity in vitro. | 2017 | Eur J Med Chem | pmid:28987604 |
| Xiao W et al. | High-dose wogonin exacerbates DSS-induced colitis by up-regulating effector T cell function and inhibiting Treg cell. | 2017 | J. Cell. Mol. Med. | pmid:27641629 |
| Salmani JMM et al. | Development of a new HPLC method for wogonin in rat plasma: Compatibility of standard and test samples. | 2017 | Acta Pharm | pmid:28858841 |
| Al-Maghout T et al. | P38 Kinase, SGK1 and NF-κB Dependent Up-Regulation of Na+/Ca2+ Exchanger Expression and Activity Following TGFß1 Treatment of Megakaryocytes. | 2017 | Cell. Physiol. Biochem. | pmid:28813704 |
| Shi G et al. | Response of human non-small-cell lung cancer cells to the influence of Wogonin with SGK1 dynamics. | 2017 | Acta Biochim. Biophys. Sin. (Shanghai) | pmid:28338770 |
| Qin X et al. | Novel platinum(IV) complexes conjugated with a wogonin derivative as multi-targeted anticancer agents. | 2017 | Bioorg. Med. Chem. | pmid:28314511 |
| Chen F et al. | Reversal of cisplatin resistance in human gastric cancer cells by a wogonin-conjugated Pt(IV) prodrug via attenuating Casein Kinase 2-mediated Nuclear Factor-κB pathways. | 2017 | Biochem. Pharmacol. | pmid:28288821 |
| Huynh DL et al. | Anti-tumor activity of wogonin, an extract from Scutellaria baicalensis, through regulating different signaling pathways. | 2017 | Chin J Nat Med | pmid:28259249 |
| Khan NM et al. | Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes. | 2017 | Free Radic. Biol. Med. | pmid:28237856 |
| Bian J et al. | Synthesis, evaluation and quantitative structure-activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28117202 |
| Lee HW et al. | Potent inhibition of monoamine oxidase A by decursin from Angelica gigas Nakai and by wogonin from Scutellaria baicalensis Georgi. | 2017 | Int. J. Biol. Macromol. | pmid:28109809 |
| Huang L et al. | Application of a new method, orthogonal projection to latent structure (OPLS) combined with principal component analysis (PCA), to screening of prostaglandin E2 production inhibitory flavonoids in Scutellaria Root. | 2016 | J Nat Med | pmid:27164908 |
| Xu Y et al. | Wogonin prevents TLR4-NF-κB-medicated neuro-inflammation and improves retinal ganglion cells survival in retina after optic nerve crush. | 2016 | Oncotarget | pmid:27756890 |
| Huang FM et al. | BisGMA-induced cytotoxicity and genotoxicity in macrophages are attenuated by wogonin via reduction of intrinsic caspase pathway activation. | 2016 | Environ. Toxicol. | pmid:26756871 |
| Sun HL et al. | Endotoxin-induced acute lung injury in mice is protected by 5,7-dihydroxy-8-methoxyflavone via inhibition of oxidative stress and HIF-1α. | 2016 | Environ. Toxicol. | pmid:26213241 |
| Xu X et al. | BM microenvironmental protection of CML cells from imatinib through Stat5/NF-κB signaling and reversal by Wogonin. | 2016 | Oncotarget | pmid:27027438 |
| Tu B et al. | Structure-activity relationship study between baicalein and wogonin by spectrometry, molecular docking and microcalorimetry. | 2016 | Food Chem | pmid:27132840 |