Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Carcinoma D002277 18 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

Download all related citations
Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Zhong Y et al. Drug resistance associates with activation of Nrf2 in MCF-7/DOX cells, and wogonin reverses it by down-regulating Nrf2-mediated cellular defense response. 2013 Mol. Carcinog. pmid:22593043
Xu F et al. The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters. 2013 J Pharm Sci pmid:24018852
Oshima N et al. Quantitative analysis of anti-inflammatory activity of orengedokuto: importance of combination of flavonoids in inhibition of PGE2 production in mouse macrophage-like cell line J774.1. 2013 J Nat Med pmid:22729955
Yu C et al. Different extraction pretreatments significantly change the flavonoid contents of Scutellaria baicalensis. 2013 Pharm Biol pmid:23738852
Wang Y et al. GSK3β/β-catenin signaling is correlated with the differentiation of glioma cells induced by wogonin. 2013 Toxicol. Lett. pmid:23872260
Zhao L et al. Enhanced 5-fluorouracil cytotoxicity in high COX-2 expressing hepatocellular carcinoma cells by wogonin via the PI3K/Akt pathway. 2013 Biochem. Cell Biol. pmid:23859016
Chirumbolo S Anticancer properties of the flavone wogonin. 2013 Toxicology pmid:23994129
Zhou YQ et al. [Recombinant soluble CD40 ligand enhances Wogonin-induced antitumor activity]. 2013 Sichuan Da Xue Xue Bao Yi Xue Ban pmid:24490490
Kim MS et al. Wogonin induces apoptosis by suppressing E6 and E7 expressions and activating intrinsic signaling pathways in HPV-16 cervical cancer cells. 2013 Cell Biol. Toxicol. pmid:23955116
Attia SM et al. Wogonin attenuates etoposide-induced oxidative DNA damage and apoptosis via suppression of oxidative DNA stress and modulation of OGG1 expression. 2013 Food Chem. Toxicol. pmid:23872129