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Protective role of wogonin against lipopolysaccharide-induced angiogenesis via VEGFR-2, not VEGFR-1. |
2006 |
Int. Immunopharmacol. |
pmid:16979123
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Wang W et al. |
Involvement of bax/bcl-2 in wogonin-induced apoptosis of human hepatoma cell line SMMC-7721. |
2006 |
Anticancer Drugs |
pmid:16926629
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Fas SC et al. |
Wogonin sensitizes resistant malignant cells to TNFalpha- and TRAIL-induced apoptosis. |
2006 |
Blood |
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[Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography]. |
2006 |
Yao Xue Xue Bao |
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Chang WT et al. |
Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments. |
2006 |
Am. J. Chin. Med. |
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Shen SC et al. |
Lipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids. |
2006 |
Neuroscience |
pmid:16580779
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Adams LS et al. |
Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. |
2006 |
Evid Based Complement Alternat Med |
pmid:16550232
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Pan MH et al. |
Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. |
2006 |
Biochem. Pharmacol. |
pmid:16949556
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Chang LC and Sun SW |
Micellar electrokinetic chromatography for separation of a mixture of coptis alkaloids, scute flavonoids, and rhubarb anthraquinones and bianthrones. |
2006 |
J Pharm Biomed Anal |
pmid:16297588
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Huang WH et al. |
Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI. |
2006 |
Biosci. Biotechnol. Biochem. |
pmid:17031041
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Zhang H et al. |
Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive. |
2006 |
J Chromatogr A |
pmid:16952364
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Zgórka G |
Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus. |
2006 |
J Chromatogr A |
pmid:16364344
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Kim YH et al. |
Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. |
2006 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:16893689
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Zhao Y et al. |
Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. |
2006 |
Eur. J. Pharmacol. |
pmid:16574098
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Tang NY et al. |
Effects of wogonin on the levels of cytokines and functions of leukocytes associated with NF-kappa B expression in Sprague-Dawley rats. |
2006 Jul-Aug |
In Vivo |
pmid:16900784
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Wang HW et al. |
Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin. |
2007 |
Int. J. Cancer |
pmid:17266043
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Hämäläinen M et al. |
Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. |
2007 |
Mediators Inflamm. |
pmid:18274639
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Jung SM et al. |
Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels. |
2007 |
Arthritis Res. Ther. |
pmid:17612394
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Kim YH et al. |
Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats. |
2007 |
Arch. Pharm. Res. |
pmid:17366750
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Ohta Y et al. |
Saikokeishito Extract Exerts a Therapeutic Effect on alpha-Naphthylisothiocyanate-Induced Liver Injury in Rats through Attenuation of Enhanced Neutrophil Infiltration and Oxidative Stress in the Liver Tissue. |
2007 |
J Clin Biochem Nutr |
pmid:18437211
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Hsieh CJ et al. |
Baicalein inhibits IL-1beta- and TNF-alpha-induced inflammatory cytokine production from human mast cells via regulation of the NF-kappaB pathway. |
2007 |
Clin Mol Allergy |
pmid:18039391
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Chang WT et al. |
Comparative effects of flavonoids on oxidant scavenging and ischemia-reperfusion injury in cardiomyocytes. |
2007 |
Eur. J. Pharmacol. |
pmid:17475241
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Lim H and Kim HP |
Inhibition of mammalian collagenase, matrix metalloproteinase-1, by naturally-occurring flavonoids. |
2007 |
Planta Med. |
pmid:17886198
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Huang GC et al. |
Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages. |
2007 |
Int. Immunopharmacol. |
pmid:17570322
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Himeji M et al. |
Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. |
2007 |
Cancer Lett. |
pmid:16497434
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Qu H et al. |
Simultaneous determination of eight active components in Chinese medicine 'YIQING' capsule using high-performance liquid chromatography. |
2007 |
J Pharm Biomed Anal |
pmid:16846714
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Yu K et al. |
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresis. |
2007 |
J Pharm Biomed Anal |
pmid:16989969
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Yu J et al. |
Antitumor activity of chloroform fraction of Scutellaria barbata and its active constituents. |
2007 |
Phytother Res |
pmid:17674423
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Seo DC et al. |
Gene expression profiling of cancer stem cell in human lung adenocarcinoma A549 cells. |
2007 |
Mol. Cancer |
pmid:18034892
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Yu JQ et al. |
Changes in mitochondrial membrane potential and reactive oxygen species during wogonin-induced cell death in human hepatoma cells. |
2007 |
Hepatol. Res. |
pmid:17300700
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Enomoto R et al. |
Wogonin prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid. |
2007 |
Ann. N. Y. Acad. Sci. |
pmid:17404053
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Lee E et al. |
Wogonin, a plant flavone, potentiates etoposide-induced apoptosis in cancer cells. |
2007 |
Ann. N. Y. Acad. Sci. |
pmid:17404065
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Guo Q et al. |
Anti-hepatitis B virus activity of wogonin in vitro and in vivo. |
2007 |
Antiviral Res. |
pmid:17280723
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Lee BS et al. |
Wogonin suppresses TARC expression induced by mite antigen via heme oxygenase 1 in human keratinocytes. Suppressive effect of wogonin on mite antigen-induced TARC expression. |
2007 |
J. Dermatol. Sci. |
pmid:17317108
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Enomoto R et al. |
Wogonin prevents glucocorticoid-induced thymocyte apoptosis without diminishing its anti-inflammatory action. |
2007 |
J. Pharmacol. Sci. |
pmid:17690528
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Park HG et al. |
Anticonvulsant effect of wogonin isolated from Scutellaria baicalensis. |
2007 |
Eur. J. Pharmacol. |
pmid:17692312
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Heo HJ et al. |
Effects of baicalin and wogonin on mucin release from cultured airway epithelial cells. |
2007 |
Phytother Res |
pmid:17622975
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Chen LG et al. |
Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. |
2008 |
Mol Nutr Food Res |
pmid:18496814
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Zhang HW et al. |
Wogonin induced differentiation and G1 phase arrest of human U-937 leukemia cells via PKCdelta phosphorylation. |
2008 |
Eur. J. Pharmacol. |
pmid:18577379
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Piao HZ et al. |
Wogonin inhibits microglial cell migration via suppression of nuclear factor-kappa B activity. |
2008 |
Int. Immunopharmacol. |
pmid:18725324
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Dai JY et al. |
Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu- tang across human intestinal Caco-2 cell monolayers. |
2008 |
Acta Pharmacol. Sin. |
pmid:18718184
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Gao J et al. |
Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. |
2008 |
J Pharm Pharm Sci |
pmid:18445366
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Lee CY et al. |
Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. |
2008 |
Liver Int. |
pmid:18346132
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Coleta M et al. |
Assessment of luteolin (3',4',5,7-tetrahydroxyflavone) neuropharmacological activity. |
2008 |
Behav. Brain Res. |
pmid:18249450
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Anand P et al. |
Cancer is a preventable disease that requires major lifestyle changes. |
2008 |
Pharm. Res. |
pmid:18626751
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Lee DH et al. |
Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. |
2008 |
Biochem. Pharmacol. |
pmid:18377871
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Makino T et al. |
Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products. |
2008 |
J Nat Med |
pmid:18404307
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Chow JM et al. |
Differential apoptotic effect of wogonin and nor-wogonin via stimulation of ROS production in human leukemia cells. |
2008 |
J. Cell. Biochem. |
pmid:17955493
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Chen S et al. |
Down-regulation of androgen-receptor and PSA by phytochemicals. |
2008 |
Int. J. Oncol. |
pmid:18202763
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Park SS et al. |
Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron. |
2008 |
J. Cell. Biochem. |
pmid:17973296
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Cole IB et al. |
Comparisons of Scutellaria baicalensis, Scutellaria lateriflora and Scutellaria racemosa: genome size, antioxidant potential and phytochemistry. |
2008 |
Planta Med. |
pmid:18484546
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Su S et al. |
Genetic characterization and phytochemical analysis of wild and cultivated populations of Scutellaria baicalensis. |
2008 |
Chem. Biodivers. |
pmid:18651621
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BÅ‚ach-Olszewska Z et al. |
Production of cytokines and stimulation of resistance to viral infection in human leukocytes by Scutellaria baicalensis flavones. |
2008 |
J. Interferon Cytokine Res. |
pmid:18771341
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Kauss T et al. |
Rutoside decreases human macrophage-derived inflammatory mediators and improves clinical signs in adjuvant-induced arthritis. |
2008 |
Arthritis Res. Ther. |
pmid:18252009
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Chung H et al. |
Anticancer effects of wogonin in both estrogen receptor-positive and -negative human breast cancer cell lines in vitro and in nude mice xenografts. |
2008 |
Int. J. Cancer |
pmid:17957784
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Kasai A et al. |
Blockade of the dioxin pathway by herbal medicine Formula Bupleuri Minor: identification of active entities for suppression of AhR activation. |
2008 |
Biol. Pharm. Bull. |
pmid:18451504
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Baumann S et al. |
Wogonin preferentially kills malignant lymphocytes and suppresses T-cell tumor growth by inducing PLCgamma1- and Ca2+-dependent apoptosis. |
2008 |
Blood |
pmid:18070986
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Li YQ et al. |
Two new alkaloids from Capparis himalayensis. |
2008 |
Chem. Pharm. Bull. |
pmid:18239306
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Zhang K et al. |
Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. |
2008 |
Cancer Sci. |
pmid:18377421
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Lu N et al. |
Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. |
2008 |
Life Sci. |
pmid:18378261
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Lin Z et al. |
Enhanced electrochemiluminescence of Ru(bpy)3(2+) by flavone compounds. |
2008 Nov-Dec |
Luminescence |
pmid:18506909
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Yin L et al. |
Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. |
2009 |
J Pharm Biomed Anal |
pmid:19264437
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Xu L et al. |
Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. |
2009 |
Anal. Chim. Acta |
pmid:19110127
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Cao H et al. |
Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. |
2009 |
J. Hazard. Mater. |
pmid:19577841
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Chen B et al. |
Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. |
2009 |
Int J Nanomedicine |
pmid:20011242
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Willimott S et al. |
An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. |
2009 |
Chem Cent J |
pmid:19785738
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Feng Y et al. |
Bear bile: dilemma of traditional medicinal use and animal protection. |
2009 |
J Ethnobiol Ethnomed |
pmid:19138420
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Ding XF et al. |
[Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. |
2009 |
Guang Pu Xue Yu Guang Pu Fen Xi |
pmid:19650472
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Li C et al. |
Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. |
2009 |
J Pharm Biomed Anal |
pmid:19481403
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Tran TD et al. |
Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. |
2009 |
Bioorg. Med. Chem. Lett. |
pmid:19233646
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Lee E et al. |
Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. |
2009 |
Ann. N. Y. Acad. Sci. |
pmid:19723047
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Qi Q et al. |
Toxicological studies of wogonin in experimental animals. |
2009 |
Phytother Res |
pmid:19003942
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Li-Weber M |
New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. |
2009 |
Cancer Treat. Rev. |
pmid:19004559
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Rushworth SA and Micheau O |
Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer. |
2009 |
Br. J. Pharmacol. |
pmid:19664138
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Peng J et al. |
Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs. |
2009 |
J Ethnopharmacol |
pmid:19397969
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Lee DH et al. |
Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin. |
2009 |
Br. J. Pharmacol. |
pmid:19438509
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Yang L et al. |
Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. |
2009 |
Biochem. Cell Biol. |
pmid:19935879
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Wohlfarth C and Efferth T |
Natural products as promising drug candidates for the treatment of hepatitis B and C. |
2009 |
Acta Pharmacol. Sin. |
pmid:19060918
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Kallifatidis G et al. |
Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. |
2009 |
Gut |
pmid:18829980
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Li J et al. |
Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. |
2009 |
J. Nat. Prod. |
pmid:19555121
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Inhibition of prostaglandin E2 production by synthetic wogonin analogs. |
2009 |
Arch. Pharm. Res. |
pmid:20091262
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Zhou XQ et al. |
[Flavonoids from Scutellaria baicalensis and their bioactivities]. |
2009 |
Beijing Da Xue Xue Bao |
pmid:19829679
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Parekh HS et al. |
A new dawn for the use of traditional Chinese medicine in cancer therapy. |
2009 |
Mol. Cancer |
pmid:19298677
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Parajuli P et al. |
In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. |
2009 |
Planta Med. |
pmid:19031366
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Si D et al. |
Mechanism of CYP2C9 inhibition by flavones and flavonols. |
2009 |
Drug Metab. Dispos. |
pmid:19074529
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Kim HS et al. |
Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. |
2009 |
J. Microbiol. Biotechnol. |
pmid:20075633
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Kaneko T et al. |
Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. |
2009 Jul-Aug |
In Vivo |
pmid:19567393
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Lu B et al. |
Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection. |
2009 Sep-Oct |
Phytochem Anal |
pmid:19533595
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Lin CW et al. |
12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCalpha/ERK/NF-kappaB-dependent MMP-9 expression. |
2010 |
J. Cell. Physiol. |
pmid:20458747
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Zhou Q et al. |
Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes. |
2010 |
Pharm. Res. |
pmid:20411407
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Wang CZ et al. |
Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. |
2010 |
Phytomedicine |
pmid:19836937
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Ye G et al. |
Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. |
2010 |
Chem. Biodivers. |
pmid:21162005
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Wei L et al. |
Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. |
2010 |
J. Cell. Biochem. |
pmid:21053277
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Lim JS et al. |
Wogonin induces differentiation and neurite outgrowth of neural precursor cells. |
2010 |
Biochem. Biophys. Res. Commun. |
pmid:20888794
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Lei W et al. |
Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. |
2010 |
Genet. Mol. Biol. |
pmid:21637484
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Ijaz AZ et al. |
MKEM: a Multi-level Knowledge Emergence Model for mining undiscovered public knowledge. |
2010 |
BMC Bioinformatics |
pmid:20406501
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Ozmen A et al. |
In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey. |
2010 |
Phytomedicine |
pmid:19576743
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Xu H et al. |
Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. |
2010 |
Bioresour. Technol. |
pmid:20708926
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Schrader KK |
Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus). |
2010 |
Toxins (Basel) |
pmid:22069655
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Kong EK et al. |
Baicalein and Wogonin inhibit collagen deposition in SHR and WKY cardiac fibroblast cultures. |
2010 |
BMB Rep |
pmid:20423617
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