Wogonin

Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene.

Cross Reference

Introduction

To understand associated biological information of Wogonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Wogonin?

Wogonin is suspected in Ischemia, Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Wogonin

MeSH term MeSH ID Detail
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Carcinoma D002277 18 associated lipids
Per page 10 20 50 | Total 24

PubChem Associated disorders and diseases

What pathways are associated with Wogonin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Wogonin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Wogonin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Wogonin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Wogonin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Wogonin

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Per page 10 20 50 100 | Total 475
Authors Title Published Journal PubMed Link
Dao TT et al. Synthesis and biological activities of 8-arylflavones. 2004 Arch. Pharm. Res. pmid:15089030
Sonoda M et al. Cytotoxic activities of flavonoids from two Scutellaria plants in Chinese medicine. 2004 J Ethnopharmacol pmid:15036470
Woźniak D et al. Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi. 2004 Nahrung pmid:15053344
Murch SJ et al. A metabolomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: discovery of novel compounds. 2004 Plant Cell Rep. pmid:15449017
Lim H et al. Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied flavonoid, wogonin. 2004 Arch. Pharm. Res. pmid:15180311
Park S et al. Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats. 2004 Dig. Dis. Sci. pmid:15139485
Cho J and Lee HK Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells. 2004 Eur. J. Pharmacol. pmid:14757129
Ong ES et al. Proteomic analysis of mouse liver for the evaluation of effects of Scutellariae radix by liquid chromatography with tandem mass spectrometry. 2004 Rapid Commun. Mass Spectrom. pmid:15468106
Chen TJ et al. Lipopolysaccharide enhancement of 12-o-tetradecanoylphorbol 13-acetate-mediated transformation in rat glioma C6, accompanied by induction of inducible nitric oxide synthase. 2004 Toxicol. Lett. pmid:14700523
Lim BO Efficacy of wogonin in the production of immunoglobulins and cytokines by mesenteric lymph node lymphocytes in mouse colitis induced with dextran sulfate sodium. 2004 Biosci. Biotechnol. Biochem. pmid:15618621
Chaudhuri PK et al. Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea. 2004 Phytother Res pmid:15022161
Tian J et al. Binding of wogonin to human serum albumin: a common binding site of wogonin in subdomain IIA. 2004 J. Photochem. Photobiol. B, Biol. pmid:15043845
Cho J and Lee HK Wogonin inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. 2004 Biol. Pharm. Bull. pmid:15467195
Piao HZ et al. Neuroprotective effect of wogonin: potential roles of inflammatory cytokines. 2004 Arch. Pharm. Res. pmid:15473663
Tai MC et al. Therapeutic potential of wogonin: a naturally occurring flavonoid. 2005 CNS Drug Rev pmid:16007236
Yoon JH and Baek SJ Molecular targets of dietary polyphenols with anti-inflammatory properties. 2005 Yonsei Med. J. pmid:16259055
Aung H et al. Scutellaria baicalensis decreases ritonavir-induced nausea. 2005 AIDS Res Ther pmid:16368007
Park EJ et al. Skullcapflavone I from Scutellaria baicalensis induces apoptosis in activated rat hepatic stellate cells. 2005 Planta Med. pmid:16206047
Jang J et al. Structure and antiinflammatory activity relationships of wogonin derivatives. 2005 Arch. Pharm. Res. pmid:16178410
Goh D et al. Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo. 2005 J. Agric. Food Chem. pmid:16218664