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Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu- tang across human intestinal Caco-2 cell monolayers. |
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Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. |
2008 |
J Pharm Pharm Sci |
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Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters. |
2008 |
Liver Int. |
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Cancer is a preventable disease that requires major lifestyle changes. |
2008 |
Pharm. Res. |
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Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells. |
2008 |
Biochem. Pharmacol. |
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Down-regulation of androgen-receptor and PSA by phytochemicals. |
2008 |
Int. J. Oncol. |
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Rutoside decreases human macrophage-derived inflammatory mediators and improves clinical signs in adjuvant-induced arthritis. |
2008 |
Arthritis Res. Ther. |
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Blockade of the dioxin pathway by herbal medicine Formula Bupleuri Minor: identification of active entities for suppression of AhR activation. |
2008 |
Biol. Pharm. Bull. |
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2008 |
Chem. Pharm. Bull. |
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Wogonin suppresses tumor growth in vivo and VEGF-induced angiogenesis through inhibiting tyrosine phosphorylation of VEGFR2. |
2008 |
Life Sci. |
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Enhanced electrochemiluminescence of Ru(bpy)3(2+) by flavone compounds. |
2008 Nov-Dec |
Luminescence |
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Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control. |
2009 |
J Pharm Biomed Anal |
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Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography. |
2009 |
Anal. Chim. Acta |
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2009 |
J. Hazard. Mater. |
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Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells. |
2009 |
Int J Nanomedicine |
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An in vitro based investigation of the cytotoxic effect of water extracts of the Chinese herbal remedy LD on cancer cells. |
2009 |
Chem Cent J |
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Bear bile: dilemma of traditional medicinal use and animal protection. |
2009 |
J Ethnobiol Ethnomed |
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2009 |
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Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. |
2009 |
J Pharm Biomed Anal |
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Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. |
2009 |
Bioorg. Med. Chem. Lett. |
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Inhibition of P-glycoprotein by wogonin is involved with the potentiation of etoposide-induced apoptosis in cancer cells. |
2009 |
Ann. N. Y. Acad. Sci. |
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Toxicological studies of wogonin in experimental animals. |
2009 |
Phytother Res |
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2009 |
Cancer Treat. Rev. |
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Molecular crosstalk between TRAIL and natural antioxidants in the treatment of cancer. |
2009 |
Br. J. Pharmacol. |
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Subchronic toxicity and plasma pharmacokinetic studies on wogonin, a natural flavonoid, in Beagle dogs. |
2009 |
J Ethnopharmacol |
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Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin. |
2009 |
Br. J. Pharmacol. |
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Wogonin induces G1 phase arrest through inhibiting Cdk4 and cyclin D1 concomitant with an elevation in p21Cip1 in human cervical carcinoma HeLa cells. |
2009 |
Biochem. Cell Biol. |
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Natural products as promising drug candidates for the treatment of hepatitis B and C. |
2009 |
Acta Pharmacol. Sin. |
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Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signalling. |
2009 |
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2009 |
J. Nat. Prod. |
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Inhibition of prostaglandin E2 production by synthetic wogonin analogs. |
2009 |
Arch. Pharm. Res. |
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2009 |
Beijing Da Xue Xue Bao |
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A new dawn for the use of traditional Chinese medicine in cancer therapy. |
2009 |
Mol. Cancer |
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In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids. |
2009 |
Planta Med. |
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Mechanism of CYP2C9 inhibition by flavones and flavonols. |
2009 |
Drug Metab. Dispos. |
pmid:19074529
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Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside. |
2009 |
J. Microbiol. Biotechnol. |
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Kaneko T et al. |
Effect of Scutellariae radix ingredients on prostaglandin E(2) production and COX-2 expression by LPS-activated macrophage. |
2009 Jul-Aug |
In Vivo |
pmid:19567393
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Lu B et al. |
Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection. |
2009 Sep-Oct |
Phytochem Anal |
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Lin CW et al. |
12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCalpha/ERK/NF-kappaB-dependent MMP-9 expression. |
2010 |
J. Cell. Physiol. |
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Use of isoform-specific UGT metabolism to determine and describe rates and profiles of glucuronidation of wogonin and oroxylin A by human liver and intestinal microsomes. |
2010 |
Pharm. Res. |
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Wang CZ et al. |
Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells. |
2010 |
Phytomedicine |
pmid:19836937
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Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry. |
2010 |
Chem. Biodivers. |
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Different apoptotic effects of wogonin via induction of H(2)O(2) generation and Ca(2+) overload in malignant hepatoma and normal hepatic cells. |
2010 |
J. Cell. Biochem. |
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Wogonin induces differentiation and neurite outgrowth of neural precursor cells. |
2010 |
Biochem. Biophys. Res. Commun. |
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Lei W et al. |
Molecular cloning and expression profiling of a chalcone synthase gene from hairy root cultures of Scutellaria viscidula Bunge. |
2010 |
Genet. Mol. Biol. |
pmid:21637484
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Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis. |
2010 |
Bioresour. Technol. |
pmid:20708926
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Schrader KK |
Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus). |
2010 |
Toxins (Basel) |
pmid:22069655
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Gao J et al. |
Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. |
2010 |
J Pharm Biomed Anal |
pmid:20457505
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Feng J et al. |
Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple. |
2010 |
J Pharm Biomed Anal |
pmid:20430560
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Kong EK et al. |
Baicalein and Wogonin inhibit collagen deposition in SHR and WKY cardiac fibroblast cultures. |
2010 |
BMB Rep |
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