2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Atherosclerosis D050197 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Thrombosis D013927 49 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Endometriosis D004715 29 associated lipids
Per page 10 20 50 | Total 25

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All references with 2,3-dinor, 6-keto-PGF1alpha

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Authors Title Published Journal PubMed Link
Jendryczko A and Tomala J An imbalance between the excretion of thromboxane and prostacyclin metabolites in women after the menopause. 1993 Zentralbl Gynakol pmid:8503234
Oates JA et al. Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man. 1984 Trans. Am. Clin. Climatol. Assoc. pmid:6433527
Piret A et al. Increased platelet aggregability and prostacyclin biosynthesis induced by intense physical exercise. 1990 Thromb. Res. pmid:2140206
Reilly IA and FitzGerald GA Eicosenoid biosynthesis and platelet function with advancing age. 1986 Thromb. Res. pmid:3754355
Vesterqvist O et al. Thromboxane and prostacyclin formation in patients with deep vein thrombosis. 1987 Thromb. Res. pmid:3554598
Vericel E et al. Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status. 1988 Thromb. Res. pmid:3129819
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Morio H et al. Effect of the infusion of OKY-046, a thromboxane A2 synthase inhibitor, on urinary metabolites of prostacyclin and thromboxane A2 in healthy human subjects. 1993 Thromb. Haemost. pmid:8470052
Tohgi H et al. Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin. 1992 Stroke pmid:1412574
Numminen H et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. 2000 Stroke pmid:10835443
Vesterqvist O et al. In vivo production of thromboxane and prostacyclin in patients following total hip arthroplasty. 1988 Scand. J. Clin. Lab. Invest. pmid:3375779
Tanaka H et al. Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A2 receptor antagonist in asthmatic patients? 1999 Respir Med pmid:10653051
Vesterqvist O et al. Synthetic arterial grafts cause prolonged increase in the in vivo formation of thromboxane and prostacyclin in humans. 1987 Res Exp Med (Berl) pmid:3303204
Rosenkranz B et al. Urinary and systemic metabolites of prostacyclin in the perfused rabbit kidney. 1982 Ren Physiol pmid:6750728
Mizugaki M et al. Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. 1999 Prostaglandins Other Lipid Mediat. pmid:10593167
Hishinuma T et al. Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. 1999 Prostaglandins Other Lipid Mediat. pmid:10593168
Hoch B and Bernhard M Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. 1999 Prostaglandins Other Lipid Mediat. pmid:10593170
Blatnik M and Steenwyk RC Quantification of urinary PGEm, 6-keto PGF(1alpha) and 2,3-dinor-6-keto PGF(1alpha) by UFLC-MS/MS before and after exercise. 2010 Prostaglandins Other Lipid Mediat. pmid:20416393
Lynch CM et al. The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy. 2011 Prostaglandins Other Lipid Mediat. pmid:21723954
Martrat A et al. Altered systemic and tissue prostacyclin in cerulein induced acute pancreatitis in rats. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1384068
Hiramatsu M et al. Application of an alpha-sidechain length-specific monoclonal antibody to immunoaffinity purification and enzyme immunoassay of 2,3-dinor-6-keto-prostaglandin F1 alpha from human urine. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:8171070
van der Weiden RM et al. Prostanoid excretion before in vitro fertilization relates to the likelihood of pregnancy. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8821123
Stichtenoth DO et al. Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728174
Pancera P et al. Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8860111
Rossi P et al. Percutaneous transluminal angioplasty increases thromboxane A2 production in claudicants. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9175173
Rossi P et al. Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:9014222
Hishinuma T et al. Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728171
Sinzinger H Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445490
Delemarre FM et al. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049696
Hishinuma T et al. Analysis of the thromboxane/prostacyclin balance in human urine by gas chromatography/selected ion monitoring: abnormalities in diabetics. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888357
Huang YS et al. Effect of indomethacin treatment on prostaglandin excretion and tissue phospholipid fatty acid composition in rats bearing mammotropic pituitary tumor, MtT-F4. 1986 Prostaglandins Leukot Med pmid:3532134
Förstermann U et al. An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A. 1989 Prostaglandins pmid:2662262
Balazy M et al. Facile method for preparation of 2,3-dinor-6-keto PGF1 alpha, the major urinary metabolite of prostacyclin. 1988 Prostaglandins pmid:3070630
Falardeau P et al. Urinary levels of 2,3-dinor-6-oxo-PGF1 alpha: a reliable index of the production of PGI2 in the spontaneously hypertensive rat. 1985 Prostaglandins pmid:3890022
Sun FF et al. Preparation of two dinor-PGI2 metabolites from 6-keto-PGF1 alpha by Mycobacterium rhodochrous. 1980 Prostaglandins pmid:6258195
Riutta A et al. Adrenaline infusion increases systemic prostacyclin production in man. 1994 Prostaglandins pmid:7972879
Vesterqvist O and Gréen K Development of a GC-MS method for quantitation of 2,3-dinor-6-keto-PGF1 alpha and determination of the urinary excretion rates in healthy humans under normal conditions and following drugs. 1984 Prostaglandins pmid:6548317
Stichtenoth DO et al. Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. 1995 Nov-Dec Prostaglandins pmid:8838242
Schaefer WR et al. Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat. 1996 Prostaglandins pmid:8875634
Neulen J et al. Arachidonic acid metabolism and prostaglandin production by primate preimplantation blastocysts. 1991 Prostaglandins pmid:1775634
Rasmanis G et al. Implications of the prognostic importance of exercise-induced thromboxane formation in survivors of an acute myocardial infarction. 1995 Prostaglandins pmid:7667506
Knapp HR and Salem N Formation of PGI3 in the rat during dietary fish oil supplementation. 1989 Prostaglandins pmid:2557651
Seyberth HW et al. Excretion of primary prostanoids and their metabolites during acute volume expansion. 1988 Prostaglandins pmid:3163156
Hamazaki T et al. Urinary excretion of PGI2/3-M and recent N-6/3 fatty acid intake. 1989 Prostaglandins pmid:2503856
Vernon WB Prostaglandins and pancreas transplantation. 1991 Prostaglandins pmid:2052737
Farker K et al. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. 1997 Prostaglandins pmid:9373880
Hotter G et al. Altered levels of tissue and urinary prostacyclin in rats subjected to pancreas transplantation. 1991 Prostaglandins pmid:2052738
Ylikorkala O et al. Urinary excretion of prostacyclin and thromboxane metabolites in climacteric women: effect of estrogen-progestin replacement therapy. 1990 Prostaglandins pmid:2106714
Henriksson P et al. Thromboxane synthase inhibition: "endoperoxide shunt phenomenon" does not occur in healthy humans in vivo. 1990 Prostaglandins pmid:2106716
Grèen K et al. Pronounced reduction of in vivo prostacyclin synthesis in humans by acetaminophen (paracetamol). 1989 Prostaglandins pmid:2664901
McAdam BF et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874808
Praticò D et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11248083
Saareks V et al. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. 2002 Pharmacol. Toxicol. pmid:12403056
Ylikorkala O et al. Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects. 1988 Obstet Gynecol pmid:3275910
Rauramo I et al. Prostacyclin and thromboxane in pregnant and nonpregnant women in response to exercise. 1995 Obstet Gynecol pmid:7770249
Yuhki K et al. [Prostaglandin I2 and its metabolites]. 2010 Nippon Rinsho pmid:20960743
Goldberg MR et al. Prostacyclin biosynthesis and platelet function in autonomic dysfunction. 1985 Neurology pmid:3838109
Fitzgerald DJ et al. Platelet activation in unstable coronary disease. 1986 N. Engl. J. Med. pmid:3531859
Alessandrini P et al. Thromboxane biosynthesis and platelet function in type I diabetes mellitus. 1988 N. Engl. J. Med. pmid:3292913
Christman BW et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. 1992 N. Engl. J. Med. pmid:1603138
FitzGerald GA et al. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. 1984 N. Engl. J. Med. pmid:6231483
Knapp HR et al. In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. 1986 N. Engl. J. Med. pmid:3007982
Falardeau P and Brash AR Quantitation of two dinor metabolites of prostacyclin by GC-MS. 1982 Meth. Enzymol. pmid:6752645
Edlund A et al. Myocardial ischaemia triggers formation of thromboxane. 1987 Lancet pmid:2887865
Gréen K et al. Deficient prostacyclin formation after acute myocardial infarction. 1987 Lancet pmid:2883378
Watson ML et al. Systemic prostaglandin I2 synthesis is normal in patients with Bartter's syndrome. 1983 Lancet pmid:6135873
Liggins GC et al. Prostacyclin and maternal lupus anticoagulant. 1984 Lancet pmid:6140483
Tulppala M et al. Thromboxane dominance and prostacyclin deficiency in habitual abortion. 1991 Lancet pmid:1672969
Stichtenoth DO et al. Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. 2005 Kidney Int. pmid:16221219
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Hashimoto K et al. Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness. 2004 J. Virol. pmid:15367596
Lin JS et al. The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence. 1992 J. Urol. pmid:1635125
Neiman J et al. Effects of a small dose of ethanol and calcium carbimide-induced acetaldehyde intoxication on human platelet aggregation, associated thromboxane formation and urinary excretion of 2,3-dinor-6-keto prostaglandin F1 alpha. 1987 J. Toxicol. Clin. Toxicol. pmid:3612897
Brown NJ et al. Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin. 1996 J. Pharmacol. Exp. Ther. pmid:8930174
Catella-Lawson F et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. 1999 J. Pharmacol. Exp. Ther. pmid:10215647
Capone ML et al. Human pharmacology of naproxen sodium. 2007 J. Pharmacol. Exp. Ther. pmid:17473175
Kuehl PG et al. Systemic production of prostacyclin and thromboxane A2 does not correlate with patency of the ductus arteriosus in very low birth weight infants. 1986 J. Pediatr. pmid:3519915
Mastrogiannis DS et al. Cocaine decreases urinary prostacyclin release in pregnancy: correlation with uterine and umbilical Doppler velocimetry. 2003 J. Matern. Fetal. Neonatal. Med. pmid:15061316
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Rasmanis G et al. Prostacyclin production in myocardial infarction in the acute phase and during follow-up. 1991 J. Intern. Med. pmid:1997639
Barden AE et al. Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia? 1999 J. Hypertens. pmid:10489109
Kimblad PO et al. Prostanoid release after lung transplantation. 1996 J. Heart Lung Transplant. pmid:8913917
Neiman J et al. Urinary excretion of 2, 3-dinor-6-keto prostaglandin F1 alpha and platelet thromboxane formation during ethanol withdrawal in alcoholics. 1987 J. Clin. Pathol. pmid:3584500
Fitzgerald DJ et al. Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis. 1988 J. Clin. Invest. pmid:3183064
Dowd NP et al. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. 2001 J. Clin. Invest. pmid:11518732
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Ylikorkala O et al. Desogestrel- and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density lipoproteins. 1987 J. Clin. Endocrinol. Metab. pmid:2960690
Ylikorkala O et al. Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants. 1986 J. Clin. Endocrinol. Metab. pmid:3536979
Mizugaki M et al. Microdetermination of 2,3-dinor-6-ketoprostaglandin F1 alpha in human urine using gas chromatography-high-resolution selected-ion monitoring. 1994 J. Chromatogr. B, Biomed. Appl. pmid:7952110
Daniel VC et al. Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry. 1994 J. Chromatogr. B, Biomed. Appl. pmid:8205238
Casas J et al. Determination of 2,3-dinor-6-ketoprostaglandin F1 alpha in urine samples by liquid chromatography and radioimmunoassay. 1986 J. Chromatogr. pmid:3558562
Ferretti A and Flanagan VP Assay of urinary 2,3-dinor-6-oxo prostaglandin F1 alpha by gas chromatography-tandem mass spectrometry. 1993 J. Chromatogr. pmid:8150859
Chiabrando C et al. Quantitative profiling of 6-ketoprostaglandin F1 alpha, 2,3-dinor-6-ketoprostaglandin F1 alpha, thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine by immunoaffinity extraction with gas chromatography-mass spectrometry. 1989 J. Chromatogr. pmid:2613794
Böger RH et al. Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin. 1995 J. Appl. Physiol. pmid:7649919
Hamm CW et al. Biochemical evidence of platelet activation in patients with persistent unstable angina. 1987 J. Am. Coll. Cardiol. pmid:3668113
Benowitz NL et al. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. 1993 J. Am. Coll. Cardiol. pmid:7691912
Lindström T et al. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. 1998 J Trauma pmid:9783614
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Schwartz JI et al. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. 2007 J Clin Pharmacol pmid:17925592