2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Atherosclerosis D050197 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Thrombosis D013927 49 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Endometriosis D004715 29 associated lipids
Ascites D001201 25 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Pregnancy Complications D011248 19 associated lipids
Down Syndrome D004314 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Angina, Unstable D000789 14 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Per page 10 20 50 | Total 25

NCBI Entrez Crosslinks

All references with 2,3-dinor, 6-keto-PGF1alpha

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Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
Arvola P et al. Exercise enhances vasorelaxation in experimental obesity associated hypertension. 1999 Cardiovasc. Res. pmid:10615427
Foudi N et al. Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. 2009 Cardiovasc. Res. pmid:18952694
Wennmalm A et al. Relation between tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in young men. 1991 Circulation pmid:2022025
Reilly IA et al. Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase. 1986 Circulation pmid:2938849
Roy L et al. Endogenous biosynthesis of prostacyclin during cardiac catheterization and angiography in man. 1985 Circulation pmid:3882264
Fitzgerald DJ et al. Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension. 1987 Circulation pmid:3552297
RÃ¥ngemark C et al. Tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in women stratified by age. 1992 Circulation pmid:1423963
Fitzgerald DJ et al. The effects of organic nitrates on prostacyclin biosynthesis and platelet function in humans. 1984 Circulation pmid:6428771
Adatia I et al. Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease. 1993 Circulation pmid:8222105
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Brown NJ et al. Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway. 2000 Circulation pmid:11056091
Capone ML et al. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. 2004 Circulation pmid:15037526
Wennmalm A et al. Excretion of thromboxane A2 and prostacyclin metabolites during treadmill exercise in patients with intermittent claudication. 1988 Clin Physiol pmid:3402185
Wennmalm A Formation of prostacyclin during administration of beta 1-selective and non-selective beta-adrenergic antagonists in healthy humans. 1992 Clin Physiol pmid:1347260
Wennmalm A et al. Maintained hyperexcretion of thromboxane A2 metabolite in healthy young cigarette smokers: results from a prospective study in randomly sampled males with stable smoking habits. 1993 Clin Physiol pmid:8519161
Cibattoni G et al. Effects of sulindac on renal and extrarenal eicosanoid synthesis. 1987 Clin. Pharmacol. Ther. pmid:3549118
Skarke C et al. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. 2012 Clin. Pharmacol. Ther. pmid:22278334
Wennmalm A et al. Non-invasive assessment of the cardiovascular eicosanoids, thromboxane A2 and prostacyclin, in randomly sampled males, with special reference to the influence of inheritance and environmental factors. 1990 Clin. Sci. pmid:2176952
Watson ML et al. Urinary kallikrein and systemic prostacyclin synthesis during sodium chloride infusion in normal man. 1985 Clin. Sci. pmid:3884237
Wennmalm A et al. 2,3-Dinor metabolites of thromboxane A2 and prostacyclin in urine from healthy human subjects: diurnal variation and relation to 24h excretion. 1992 Clin. Sci. pmid:1330409
RÃ¥ngemark C and Wennmalm A Cigarette smoking and urinary excretion of markers for platelet/vessel wall interaction in healthy women. 1991 Clin. Sci. pmid:1649717
Förstermann U and Feuerstein TJ Decreased systemic formation of prostaglandin E and prostacyclin, and unchanged thromboxane formation, in alcoholics during withdrawal as estimated from metabolites in urine. 1987 Clin. Sci. pmid:3308287
Watson ML et al. Prostaglandins and kallikrein during volume expansion in normal man. 1984 Contrib Nephrol pmid:6570094
Rautanen M et al. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. 1997 Crit. Care Med. pmid:9233750
Koivisto VA et al. Stimulation of prostacyclin synthesis by physical exercise in type I diabetes. 1989 Diabetes Care pmid:2507264
Closa D et al. Changes of systemic prostacyclin and thromboxane A2 in sodium taurocholate- and cerulein-induced acute pancreatitis in rats. 1993 Dig. Dis. Sci. pmid:7678383
Ross S et al. Association of cyclooxygenase-2 genetic variant with cardiovascular disease. 2014 Eur. Heart J. pmid:24796340
Lahoz C et al. Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure. 1997 Eur. J. Clin. Invest. pmid:9352251
Vesterqvist O and Gréen K Effects of naproxen on the in vivo synthesis of thromboxane and prostacyclin in man. 1989 Eur. J. Clin. Pharmacol. pmid:2515064
Vesterqvist O Rapid recovery of in vivo prostacyclin formation after inhibition by aspirin. Evidence from measurements of the major urinary metabolite of prostacyclin by GC-MS. 1986 Eur. J. Clin. Pharmacol. pmid:3519239
Larsson PT et al. Metoprolol does not reduce platelet aggregability during sympatho-adrenal stimulation. 1992 Eur. J. Clin. Pharmacol. pmid:1387607
Edlund A et al. Acipimox stimulates skin blood flow by a cyclo-oxygenase-dependent mechanism. 1990 Eur. J. Clin. Pharmacol. pmid:2125938
Greer IA et al. Synergistic inhibitory effects of adrenoceptor antagonists and prostacyclin, and umbilical artery-derived prostacyclin-like activity on platelet aggregation. 1990 May-Jun Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:1970789
Watson ML et al. Systemic synthesis of prostaglandin I2 following sustained infusion of angiotensin II in conscious dogs. 1986 Eur. J. Pharmacol. pmid:3530786
Guarner F et al. Increased synthesis of systemic prostacyclin in cirrhotic patients. 1986 Gastroenterology pmid:3510938
Guarner C et al. Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination. 1992 Gastroenterology pmid:1727763
Martineau A et al. Defective synthesis of vasodilator prostaglandins in the spontaneously hypertensive rat. 1984 Mar-Apr Hypertension pmid:6373595
Falardeau P and Martineau A In vivo production of prostaglandin I2 in Dahl salt-sensitive and salt-resistant rats. 1983 Sep-Oct Hypertension pmid:6352480
Minuz P et al. Altered excretion of prostaglandin and thromboxane metabolites in pregnancy-induced hypertension. 1988 Hypertension pmid:3290103
Arnaud J et al. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites. 2007 J Am Coll Nutr pmid:17914127
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
Schwartz JI et al. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. 2007 J Clin Pharmacol pmid:17925592
Ritter JM et al. Prostacyclin biosynthesis in essential hypertension before and during treatment. 1996 J Hum Hypertens pmid:8642189
Lindström T et al. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. 1998 J Trauma pmid:9783614
Hamm CW et al. Biochemical evidence of platelet activation in patients with persistent unstable angina. 1987 J. Am. Coll. Cardiol. pmid:3668113
Benowitz NL et al. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. 1993 J. Am. Coll. Cardiol. pmid:7691912
Böger RH et al. Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin. 1995 J. Appl. Physiol. pmid:7649919
Casas J et al. Determination of 2,3-dinor-6-ketoprostaglandin F1 alpha in urine samples by liquid chromatography and radioimmunoassay. 1986 J. Chromatogr. pmid:3558562
Ferretti A and Flanagan VP Assay of urinary 2,3-dinor-6-oxo prostaglandin F1 alpha by gas chromatography-tandem mass spectrometry. 1993 J. Chromatogr. pmid:8150859
Chiabrando C et al. Quantitative profiling of 6-ketoprostaglandin F1 alpha, 2,3-dinor-6-ketoprostaglandin F1 alpha, thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine by immunoaffinity extraction with gas chromatography-mass spectrometry. 1989 J. Chromatogr. pmid:2613794