2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Atherosclerosis D050197 85 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Thrombosis D013927 49 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Endometriosis D004715 29 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Ascites D001201 25 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Pregnancy Complications D011248 19 associated lipids
Down Syndrome D004314 18 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Angina, Unstable D000789 14 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Respiratory Syncytial Virus Infections D018357 10 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Per page 10 20 50 | Total 25

NCBI Entrez Crosslinks

All references with 2,3-dinor, 6-keto-PGF1alpha

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Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
Falardeau P et al. Urinary levels of 2,3-dinor-6-oxo-PGF1 alpha: a reliable index of the production of PGI2 in the spontaneously hypertensive rat. 1985 Prostaglandins pmid:3890022
McAdam BF et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874808
Praticò D et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11248083
Saareks V et al. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. 2002 Pharmacol. Toxicol. pmid:12403056
Ylikorkala O et al. Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects. 1988 Obstet Gynecol pmid:3275910
Rauramo I et al. Prostacyclin and thromboxane in pregnant and nonpregnant women in response to exercise. 1995 Obstet Gynecol pmid:7770249
Yuhki K et al. [Prostaglandin I2 and its metabolites]. 2010 Nippon Rinsho pmid:20960743
Goldberg MR et al. Prostacyclin biosynthesis and platelet function in autonomic dysfunction. 1985 Neurology pmid:3838109
Fitzgerald DJ et al. Platelet activation in unstable coronary disease. 1986 N. Engl. J. Med. pmid:3531859
Alessandrini P et al. Thromboxane biosynthesis and platelet function in type I diabetes mellitus. 1988 N. Engl. J. Med. pmid:3292913
Christman BW et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. 1992 N. Engl. J. Med. pmid:1603138
FitzGerald GA et al. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. 1984 N. Engl. J. Med. pmid:6231483
Knapp HR et al. In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. 1986 N. Engl. J. Med. pmid:3007982
Falardeau P and Brash AR Quantitation of two dinor metabolites of prostacyclin by GC-MS. 1982 Meth. Enzymol. pmid:6752645
Edlund A et al. Myocardial ischaemia triggers formation of thromboxane. 1987 Lancet pmid:2887865
Gréen K et al. Deficient prostacyclin formation after acute myocardial infarction. 1987 Lancet pmid:2883378
Watson ML et al. Systemic prostaglandin I2 synthesis is normal in patients with Bartter's syndrome. 1983 Lancet pmid:6135873
Liggins GC et al. Prostacyclin and maternal lupus anticoagulant. 1984 Lancet pmid:6140483
Tulppala M et al. Thromboxane dominance and prostacyclin deficiency in habitual abortion. 1991 Lancet pmid:1672969
Stichtenoth DO et al. Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. 2005 Kidney Int. pmid:16221219
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Hashimoto K et al. Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness. 2004 J. Virol. pmid:15367596
Lin JS et al. The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence. 1992 J. Urol. pmid:1635125
Neiman J et al. Effects of a small dose of ethanol and calcium carbimide-induced acetaldehyde intoxication on human platelet aggregation, associated thromboxane formation and urinary excretion of 2,3-dinor-6-keto prostaglandin F1 alpha. 1987 J. Toxicol. Clin. Toxicol. pmid:3612897
Brown NJ et al. Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin. 1996 J. Pharmacol. Exp. Ther. pmid:8930174
Catella-Lawson F et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. 1999 J. Pharmacol. Exp. Ther. pmid:10215647
Capone ML et al. Human pharmacology of naproxen sodium. 2007 J. Pharmacol. Exp. Ther. pmid:17473175
Kuehl PG et al. Systemic production of prostacyclin and thromboxane A2 does not correlate with patency of the ductus arteriosus in very low birth weight infants. 1986 J. Pediatr. pmid:3519915
Mastrogiannis DS et al. Cocaine decreases urinary prostacyclin release in pregnancy: correlation with uterine and umbilical Doppler velocimetry. 2003 J. Matern. Fetal. Neonatal. Med. pmid:15061316
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Rasmanis G et al. Prostacyclin production in myocardial infarction in the acute phase and during follow-up. 1991 J. Intern. Med. pmid:1997639
Barden AE et al. Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia? 1999 J. Hypertens. pmid:10489109
Kimblad PO et al. Prostanoid release after lung transplantation. 1996 J. Heart Lung Transplant. pmid:8913917
Neiman J et al. Urinary excretion of 2, 3-dinor-6-keto prostaglandin F1 alpha and platelet thromboxane formation during ethanol withdrawal in alcoholics. 1987 J. Clin. Pathol. pmid:3584500
Fitzgerald DJ et al. Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis. 1988 J. Clin. Invest. pmid:3183064
Dowd NP et al. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. 2001 J. Clin. Invest. pmid:11518732
Song WL et al. Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. 2012 J. Clin. Invest. pmid:22406532
Ylikorkala O et al. Desogestrel- and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density lipoproteins. 1987 J. Clin. Endocrinol. Metab. pmid:2960690
Ylikorkala O et al. Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants. 1986 J. Clin. Endocrinol. Metab. pmid:3536979
Mizugaki M et al. Microdetermination of 2,3-dinor-6-ketoprostaglandin F1 alpha in human urine using gas chromatography-high-resolution selected-ion monitoring. 1994 J. Chromatogr. B, Biomed. Appl. pmid:7952110
Daniel VC et al. Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry. 1994 J. Chromatogr. B, Biomed. Appl. pmid:8205238
Casas J et al. Determination of 2,3-dinor-6-ketoprostaglandin F1 alpha in urine samples by liquid chromatography and radioimmunoassay. 1986 J. Chromatogr. pmid:3558562
Ferretti A and Flanagan VP Assay of urinary 2,3-dinor-6-oxo prostaglandin F1 alpha by gas chromatography-tandem mass spectrometry. 1993 J. Chromatogr. pmid:8150859
Chiabrando C et al. Quantitative profiling of 6-ketoprostaglandin F1 alpha, 2,3-dinor-6-ketoprostaglandin F1 alpha, thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine by immunoaffinity extraction with gas chromatography-mass spectrometry. 1989 J. Chromatogr. pmid:2613794
Böger RH et al. Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin. 1995 J. Appl. Physiol. pmid:7649919
Hamm CW et al. Biochemical evidence of platelet activation in patients with persistent unstable angina. 1987 J. Am. Coll. Cardiol. pmid:3668113
Benowitz NL et al. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. 1993 J. Am. Coll. Cardiol. pmid:7691912
Lindström T et al. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. 1998 J Trauma pmid:9783614
Ritter JM et al. Prostacyclin biosynthesis in essential hypertension before and during treatment. 1996 J Hum Hypertens pmid:8642189
Schwartz JI et al. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. 2007 J Clin Pharmacol pmid:17925592