2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Tibial Fractures D013978 4 associated lipids
Thrombosis D013927 49 associated lipids
Endometriosis D004715 29 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Hypertension D006973 115 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Carotid Artery Thrombosis D002341 7 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Angina, Unstable D000789 14 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Ascites D001201 25 associated lipids
Down Syndrome D004314 18 associated lipids
Bartter Syndrome D001477 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Per page 10 20 50 | Total 25

NCBI Entrez Crosslinks

All references with 2,3-dinor, 6-keto-PGF1alpha

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Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
McAdam BF et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874808
Lindström T et al. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. 1998 J Trauma pmid:9783614
Regan CL et al. Reduced fetal exposure to aspirin using a novel controlled-release preparation in normotensive and hypertensive pregnancies. 1998 Br J Obstet Gynaecol pmid:9692413
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Farker K et al. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. 1997 Prostaglandins pmid:9373880
Lahoz C et al. Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure. 1997 Eur. J. Clin. Invest. pmid:9352251
Rautanen M et al. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. 1997 Crit. Care Med. pmid:9233750
Rossi P et al. Percutaneous transluminal angioplasty increases thromboxane A2 production in claudicants. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9175173
Henrion D et al. Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2. 1997 Br. J. Pharmacol. pmid:9146891
van der Weiden RM et al. Prostanoid excretion in incipient singleton and twin pregnancies. 1996 Am. J. Obstet. Gynecol. pmid:9065139
Rossi P et al. Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:9014222
Brown NJ et al. Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin. 1996 J. Pharmacol. Exp. Ther. pmid:8930174
Kimblad PO et al. Prostanoid release after lung transplantation. 1996 J. Heart Lung Transplant. pmid:8913917
Hishinuma T et al. Analysis of the thromboxane/prostacyclin balance in human urine by gas chromatography/selected ion monitoring: abnormalities in diabetics. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888357
Schaefer WR et al. Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat. 1996 Prostaglandins pmid:8875634
Pancera P et al. Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8860111
Stichtenoth DO et al. Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. 1995 Nov-Dec Prostaglandins pmid:8838242
van der Weiden RM et al. Prostanoid excretion before in vitro fertilization relates to the likelihood of pregnancy. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:8821123
Ritter JM et al. Prostacyclin biosynthesis in essential hypertension before and during treatment. 1996 J Hum Hypertens pmid:8642189
Wennmalm A et al. Maintained hyperexcretion of thromboxane A2 metabolite in healthy young cigarette smokers: results from a prospective study in randomly sampled males with stable smoking habits. 1993 Clin Physiol pmid:8519161
Jendryczko A and Tomala J An imbalance between the excretion of thromboxane and prostacyclin metabolites in women after the menopause. 1993 Zentralbl Gynakol pmid:8503234
O'Brien WF et al. The effect of acetaminophen on prostacyclin production in pregnant women. 1993 Am. J. Obstet. Gynecol. pmid:8475962
Morio H et al. Effect of the infusion of OKY-046, a thromboxane A2 synthase inhibitor, on urinary metabolites of prostacyclin and thromboxane A2 in healthy human subjects. 1993 Thromb. Haemost. pmid:8470052
Chen HI et al. Effects of exercise training on the biosynthesis of prostacyclin and thromboxane in rats. 1993 Acta Physiol. Scand. pmid:8452036
Foulon I et al. Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619. 1993 Arterioscler. Thromb. pmid:8443146
Adatia I et al. Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease. 1993 Br Heart J pmid:8435245
Bordet JC et al. Systemic but not renal production of prostacyclin is highly reduced in cyclosporin-treated heart transplant recipients. 1993 Am. J. Cardiol. pmid:8352201
Adatia I et al. Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease. 1993 Circulation pmid:8222105
Daniel VC et al. Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry. 1994 J. Chromatogr. B, Biomed. Appl. pmid:8205238
Barden A et al. Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy. 1994 Blood Press. pmid:8199718
Hiramatsu M et al. Application of an alpha-sidechain length-specific monoclonal antibody to immunoaffinity purification and enzyme immunoassay of 2,3-dinor-6-keto-prostaglandin F1 alpha from human urine. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:8171070
Ferretti A and Flanagan VP Assay of urinary 2,3-dinor-6-oxo prostaglandin F1 alpha by gas chromatography-tandem mass spectrometry. 1993 J. Chromatogr. pmid:8150859
Riutta A et al. Selective solid-phase extraction of urinary 2,3-dinor-6-ketoprostaglandin F1 alpha for determination with radioimmunoassay. 1994 Anal. Biochem. pmid:7978278
Riutta A et al. Adrenaline infusion increases systemic prostacyclin production in man. 1994 Prostaglandins pmid:7972879
Mizugaki M et al. Microdetermination of 2,3-dinor-6-ketoprostaglandin F1 alpha in human urine using gas chromatography-high-resolution selected-ion monitoring. 1994 J. Chromatogr. B, Biomed. Appl. pmid:7952110
Rauramo I et al. Prostacyclin and thromboxane in pregnant and nonpregnant women in response to exercise. 1995 Obstet Gynecol pmid:7770249
Benowitz NL et al. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking. 1993 J. Am. Coll. Cardiol. pmid:7691912
Closa D et al. Changes of systemic prostacyclin and thromboxane A2 in sodium taurocholate- and cerulein-induced acute pancreatitis in rats. 1993 Dig. Dis. Sci. pmid:7678383
Rasmanis G et al. Implications of the prognostic importance of exercise-induced thromboxane formation in survivors of an acute myocardial infarction. 1995 Prostaglandins pmid:7667506
Böger RH et al. Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin. 1995 J. Appl. Physiol. pmid:7649919
Falardeau P et al. Quantitative analysis of two dinor urinary metabolites of prostaglandin I2. 1981 Anal. Biochem. pmid:7030131
Falardeau P and Brash AR Quantitation of two dinor metabolites of prostacyclin by GC-MS. 1982 Meth. Enzymol. pmid:6752645
Rosenkranz B et al. Urinary and systemic metabolites of prostacyclin in the perfused rabbit kidney. 1982 Ren Physiol pmid:6750728
Watson ML et al. Prostaglandins and kallikrein during volume expansion in normal man. 1984 Contrib Nephrol pmid:6570094
Vesterqvist O and Gréen K Development of a GC-MS method for quantitation of 2,3-dinor-6-keto-PGF1 alpha and determination of the urinary excretion rates in healthy humans under normal conditions and following drugs. 1984 Prostaglandins pmid:6548317
Oates JA et al. Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man. 1984 Trans. Am. Clin. Climatol. Assoc. pmid:6433527
Fitzgerald DJ et al. The effects of organic nitrates on prostacyclin biosynthesis and platelet function in humans. 1984 Circulation pmid:6428771
Martineau A et al. Defective synthesis of vasodilator prostaglandins in the spontaneously hypertensive rat. 1984 Mar-Apr Hypertension pmid:6373595
Falardeau P and Martineau A In vivo production of prostaglandin I2 in Dahl salt-sensitive and salt-resistant rats. 1983 Sep-Oct Hypertension pmid:6352480
Fischer S et al. Prostacyclin metabolism in adults and neonates. Urinary profiles of 6-ketoprostaglandin F1 alpha and 2,3-dinor-6-ketoprostaglandin F1 alpha studied by gas chromatography-mass spectrometry. 1983 Biochim. Biophys. Acta pmid:6337642
Sun FF et al. Preparation of two dinor-PGI2 metabolites from 6-keto-PGF1 alpha by Mycobacterium rhodochrous. 1980 Prostaglandins pmid:6258195
FitzGerald GA et al. Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation. 1984 N. Engl. J. Med. pmid:6231483
Liggins GC et al. Prostacyclin and maternal lupus anticoagulant. 1984 Lancet pmid:6140483
Watson ML et al. Systemic prostaglandin I2 synthesis is normal in patients with Bartter's syndrome. 1983 Lancet pmid:6135873
Falardeau P et al. Urinary levels of 2,3-dinor-6-oxo-PGF1 alpha: a reliable index of the production of PGI2 in the spontaneously hypertensive rat. 1985 Prostaglandins pmid:3890022
Watson ML et al. Urinary kallikrein and systemic prostacyclin synthesis during sodium chloride infusion in normal man. 1985 Clin. Sci. pmid:3884237
Roy L et al. Endogenous biosynthesis of prostacyclin during cardiac catheterization and angiography in man. 1985 Circulation pmid:3882264
Goldberg MR et al. Prostacyclin biosynthesis and platelet function in autonomic dysfunction. 1985 Neurology pmid:3838109
Reilly IA and FitzGerald GA Eicosenoid biosynthesis and platelet function with advancing age. 1986 Thromb. Res. pmid:3754355
Fischer S et al. Formation of prostacyclin and thromboxane in man as measured by the main urinary metabolites. 1986 Biochim. Biophys. Acta pmid:3754157
Hamm CW et al. Biochemical evidence of platelet activation in patients with persistent unstable angina. 1987 J. Am. Coll. Cardiol. pmid:3668113
Neiman J et al. Effects of a small dose of ethanol and calcium carbimide-induced acetaldehyde intoxication on human platelet aggregation, associated thromboxane formation and urinary excretion of 2,3-dinor-6-keto prostaglandin F1 alpha. 1987 J. Toxicol. Clin. Toxicol. pmid:3612897
Neiman J et al. Urinary excretion of 2, 3-dinor-6-keto prostaglandin F1 alpha and platelet thromboxane formation during ethanol withdrawal in alcoholics. 1987 J. Clin. Pathol. pmid:3584500
Casas J et al. Determination of 2,3-dinor-6-ketoprostaglandin F1 alpha in urine samples by liquid chromatography and radioimmunoassay. 1986 J. Chromatogr. pmid:3558562
Vesterqvist O et al. Thromboxane and prostacyclin formation in patients with deep vein thrombosis. 1987 Thromb. Res. pmid:3554598
Fitzgerald DJ et al. Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension. 1987 Circulation pmid:3552297
Cibattoni G et al. Effects of sulindac on renal and extrarenal eicosanoid synthesis. 1987 Clin. Pharmacol. Ther. pmid:3549118
Nowak J et al. Vascular effects of infused adenosine are not mediated by prostacyclin release in humans. 1987 Am. J. Physiol. pmid:3548440
Ylikorkala O et al. Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants. 1986 J. Clin. Endocrinol. Metab. pmid:3536979
Huang YS et al. Effect of indomethacin treatment on prostaglandin excretion and tissue phospholipid fatty acid composition in rats bearing mammotropic pituitary tumor, MtT-F4. 1986 Prostaglandins Leukot Med pmid:3532134
Fitzgerald DJ et al. Platelet activation in unstable coronary disease. 1986 N. Engl. J. Med. pmid:3531859
Watson ML et al. Systemic synthesis of prostaglandin I2 following sustained infusion of angiotensin II in conscious dogs. 1986 Eur. J. Pharmacol. pmid:3530786
Henriksson P et al. In vivo production of prostacyclin and thromboxane in patients with acute myocardial infarction. 1986 Br Heart J pmid:3521690
Kuehl PG et al. Systemic production of prostacyclin and thromboxane A2 does not correlate with patency of the ductus arteriosus in very low birth weight infants. 1986 J. Pediatr. pmid:3519915
Vesterqvist O Rapid recovery of in vivo prostacyclin formation after inhibition by aspirin. Evidence from measurements of the major urinary metabolite of prostacyclin by GC-MS. 1986 Eur. J. Clin. Pharmacol. pmid:3519239
Guarner F et al. Increased synthesis of systemic prostacyclin in cirrhotic patients. 1986 Gastroenterology pmid:3510938
Neiman J et al. Platelet function during acetaldehyde intoxication in healthy male volunteers. 1987 Alcohol Alcohol Suppl pmid:3426736
Wennmalm A et al. Excretion of thromboxane A2 and prostacyclin metabolites during treadmill exercise in patients with intermittent claudication. 1988 Clin Physiol pmid:3402185
Vesterqvist O et al. In vivo production of thromboxane and prostacyclin in patients following total hip arthroplasty. 1988 Scand. J. Clin. Lab. Invest. pmid:3375779
Förstermann U and Feuerstein TJ Decreased systemic formation of prostaglandin E and prostacyclin, and unchanged thromboxane formation, in alcoholics during withdrawal as estimated from metabolites in urine. 1987 Clin. Sci. pmid:3308287
Vesterqvist O et al. Synthetic arterial grafts cause prolonged increase in the in vivo formation of thromboxane and prostacyclin in humans. 1987 Res Exp Med (Berl) pmid:3303204
Alessandrini P et al. Thromboxane biosynthesis and platelet function in type I diabetes mellitus. 1988 N. Engl. J. Med. pmid:3292913
Gréen K et al. Urinary metabolites of thromboxane and prostacyclin in diabetes mellitus. 1988 Acta Endocrinol. pmid:3291538
Minuz P et al. Altered excretion of prostaglandin and thromboxane metabolites in pregnancy-induced hypertension. 1988 Hypertension pmid:3290103
Ylikorkala O et al. Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects. 1988 Obstet Gynecol pmid:3275910
Fitzgerald DJ et al. Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis. 1988 J. Clin. Invest. pmid:3183064
Seyberth HW et al. Excretion of primary prostanoids and their metabolites during acute volume expansion. 1988 Prostaglandins pmid:3163156
Lassila R et al. Vasoactive and atherogenic effects of cigarette smoking: a study of monozygotic twins discordant for smoking. 1988 BMJ pmid:3142565
Vericel E et al. Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status. 1988 Thromb. Res. pmid:3129819
Reilly IA et al. Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon. 1986 Br Med J (Clin Res Ed) pmid:3083991
Rosenkranz B et al. Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man. 1986 Br J Clin Pharmacol pmid:3083851
Balazy M et al. Facile method for preparation of 2,3-dinor-6-keto PGF1 alpha, the major urinary metabolite of prostacyclin. 1988 Prostaglandins pmid:3070630
Knapp HR et al. In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. 1986 N. Engl. J. Med. pmid:3007982
Ylikorkala O et al. Desogestrel- and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density lipoproteins. 1987 J. Clin. Endocrinol. Metab. pmid:2960690
Castagnoli MN et al. Combined high-performance liquid chromatography and enzyme immunoassay for the determination of urinary metabolites of thromboxane and 6-keto-PGF1 alpha. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960164
Ciabattoni G et al. Radioimmunoassay measurement of 2,3-dinor metabolites of prostacyclin and thromboxane in human urine. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960163
Edlund A et al. Leg exercise increases prostacyclin synthesis without activating platelets in both healthy and atherosclerotic humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959097
Gréen K and Vesterqvist O In vivo synthesis of thromboxane A2 and prostaglandin I2 in healthy and diseased individuals. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959096
Gréen K and Vesterqvist O In vivo synthesis of thromboxane and prostacyclin in man in health and disease. Data from GC-MS measurements of major urinary metabolites. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949557
Reilly IA et al. Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase. 1986 Circulation pmid:2938849