2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Tibial Fractures D013978 4 associated lipids
Thrombosis D013927 49 associated lipids
Endometriosis D004715 29 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Hypertension D006973 115 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Carotid Artery Thrombosis D002341 7 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Angina, Unstable D000789 14 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Ascites D001201 25 associated lipids
Down Syndrome D004314 18 associated lipids
Bartter Syndrome D001477 5 associated lipids
Atherosclerosis D050197 85 associated lipids
Per page 10 20 50 | Total 25

NCBI Entrez Crosslinks

All references with 2,3-dinor, 6-keto-PGF1alpha

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Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
pmid:
Catella-Lawson F et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. 1999 J. Pharmacol. Exp. Ther. pmid:10215647
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Barden AE et al. Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia? 1999 J. Hypertens. pmid:10489109
Mizugaki M et al. Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. 1999 Prostaglandins Other Lipid Mediat. pmid:10593167
Hishinuma T et al. Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. 1999 Prostaglandins Other Lipid Mediat. pmid:10593168
Hoch B and Bernhard M Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. 1999 Prostaglandins Other Lipid Mediat. pmid:10593170
Arvola P et al. Exercise enhances vasorelaxation in experimental obesity associated hypertension. 1999 Cardiovasc. Res. pmid:10615427
Tanaka H et al. Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A2 receptor antagonist in asthmatic patients? 1999 Respir Med pmid:10653051
Numminen H et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. 2000 Stroke pmid:10835443
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Delemarre FM et al. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049696
Brown NJ et al. Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway. 2000 Circulation pmid:11056091
Praticò D et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11248083
Dowd NP et al. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. 2001 J. Clin. Invest. pmid:11518732
Kaaja R et al. Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins. 2001 Br. J. Haematol. pmid:11552994
Hishinuma T et al. Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728171
Stichtenoth DO et al. Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728174
Saareks V et al. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. 2002 Pharmacol. Toxicol. pmid:12403056
Sinzinger H Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445490
Kudolo GB et al. Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. 2002 Thromb. Res. pmid:12590952
Wennmalm A et al. 2,3-Dinor metabolites of thromboxane A2 and prostacyclin in urine from healthy human subjects: diurnal variation and relation to 24h excretion. 1992 Clin. Sci. pmid:1330409
Wennmalm A Formation of prostacyclin during administration of beta 1-selective and non-selective beta-adrenergic antagonists in healthy humans. 1992 Clin Physiol pmid:1347260
Martrat A et al. Altered systemic and tissue prostacyclin in cerulein induced acute pancreatitis in rats. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1384068
Larsson PT et al. Metoprolol does not reduce platelet aggregability during sympatho-adrenal stimulation. 1992 Eur. J. Clin. Pharmacol. pmid:1387607
Tohgi H et al. Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin. 1992 Stroke pmid:1412574
RÃ¥ngemark C et al. Tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in women stratified by age. 1992 Circulation pmid:1423963
Capone ML et al. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. 2004 Circulation pmid:15037526
Mastrogiannis DS et al. Cocaine decreases urinary prostacyclin release in pregnancy: correlation with uterine and umbilical Doppler velocimetry. 2003 J. Matern. Fetal. Neonatal. Med. pmid:15061316
Hashimoto K et al. Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness. 2004 J. Virol. pmid:15367596
Vainio M et al. Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. 2004 Acta Obstet Gynecol Scand pmid:15548142
Saloheimo P et al. Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage. 2005 Thromb. Res. pmid:15733969
Christman BW et al. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension. 1992 N. Engl. J. Med. pmid:1603138
Stichtenoth DO et al. Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. 2005 Kidney Int. pmid:16221219
Lin JS et al. The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence. 1992 J. Urol. pmid:1635125
RÃ¥ngemark C and Wennmalm A Cigarette smoking and urinary excretion of markers for platelet/vessel wall interaction in healthy women. 1991 Clin. Sci. pmid:1649717
Tulppala M et al. Thromboxane dominance and prostacyclin deficiency in habitual abortion. 1991 Lancet pmid:1672969
Stergioulas AT and Filippou DK Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study. 2006 Appl Physiol Nutr Metab pmid:16900233
Guarner C et al. Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination. 1992 Gastroenterology pmid:1727763
Kurki T et al. Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin. 1992 Am. J. Obstet. Gynecol. pmid:1733190
Capone ML et al. Human pharmacology of naproxen sodium. 2007 J. Pharmacol. Exp. Ther. pmid:17473175
Neulen J et al. Arachidonic acid metabolism and prostaglandin production by primate preimplantation blastocysts. 1991 Prostaglandins pmid:1775634
Arnaud J et al. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites. 2007 J Am Coll Nutr pmid:17914127
Schwartz JI et al. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. 2007 J Clin Pharmacol pmid:17925592
Aitokallio-Tallberg AM et al. Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma. 1991 Cancer Res. pmid:1868436
Signore C et al. Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. 2008 Alcohol. Clin. Exp. Res. pmid:18715278
Presser SC et al. Simultaneous measurements of prostacyclin and thromboxane metabolites during the menstrual cycle. 1991 Am. J. Obstet. Gynecol. pmid:1892191
Foudi N et al. Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. 2009 Cardiovasc. Res. pmid:18952694
Zhao L et al. Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. 2009 Br. J. Pharmacol. pmid:19220291
Ward PS et al. Excretion of metabolites of prostacyclin and thromboxane by rats with nephrotoxic nephritis: effects of interleukin-1. 1991 Br. J. Pharmacol. pmid:1933130
Greer IA et al. Synergistic inhibitory effects of adrenoceptor antagonists and prostacyclin, and umbilical artery-derived prostacyclin-like activity on platelet aggregation. 1990 May-Jun Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:1970789
Foudi N et al. Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits. 2009 Am. J. Physiol. Heart Circ. Physiol. pmid:19783781
Rasmanis G et al. Prostacyclin production in myocardial infarction in the acute phase and during follow-up. 1991 J. Intern. Med. pmid:1997639
Wennmalm A et al. Relation between tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in young men. 1991 Circulation pmid:2022025
Blatnik M and Steenwyk RC Quantification of urinary PGEm, 6-keto PGF(1alpha) and 2,3-dinor-6-keto PGF(1alpha) by UFLC-MS/MS before and after exercise. 2010 Prostaglandins Other Lipid Mediat. pmid:20416393
Vernon WB Prostaglandins and pancreas transplantation. 1991 Prostaglandins pmid:2052737
Hotter G et al. Altered levels of tissue and urinary prostacyclin in rats subjected to pancreas transplantation. 1991 Prostaglandins pmid:2052738
Fukushima H et al. Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. 2010 Am. J. Med. Genet. A pmid:20583254
Yuhki K et al. [Prostaglandin I2 and its metabolites]. 2010 Nippon Rinsho pmid:20960743
Ylikorkala O et al. Urinary excretion of prostacyclin and thromboxane metabolites in climacteric women: effect of estrogen-progestin replacement therapy. 1990 Prostaglandins pmid:2106714
Henriksson P et al. Thromboxane synthase inhibition: "endoperoxide shunt phenomenon" does not occur in healthy humans in vivo. 1990 Prostaglandins pmid:2106716
Edlund A et al. Acipimox stimulates skin blood flow by a cyclo-oxygenase-dependent mechanism. 1990 Eur. J. Clin. Pharmacol. pmid:2125938
Piret A et al. Increased platelet aggregability and prostacyclin biosynthesis induced by intense physical exercise. 1990 Thromb. Res. pmid:2140206
Lynch CM et al. The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy. 2011 Prostaglandins Other Lipid Mediat. pmid:21723954
Wennmalm A et al. Non-invasive assessment of the cardiovascular eicosanoids, thromboxane A2 and prostacyclin, in randomly sampled males, with special reference to the influence of inheritance and environmental factors. 1990 Clin. Sci. pmid:2176952
Skarke C et al. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. 2012 Clin. Pharmacol. Ther. pmid:22278334
Song WL et al. Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. 2012 J. Clin. Invest. pmid:22406532
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Ross S et al. Association of cyclooxygenase-2 genetic variant with cardiovascular disease. 2014 Eur. Heart J. pmid:24796340
Hamazaki T et al. Urinary excretion of PGI2/3-M and recent N-6/3 fatty acid intake. 1989 Prostaglandins pmid:2503856
Ruth V et al. Urinary excretion of prostacyclin metabolites in infants born after maternal preeclampsia or with birth asphyxia. 1989 Biol. Neonate pmid:2506939
Koivisto VA et al. Stimulation of prostacyclin synthesis by physical exercise in type I diabetes. 1989 Diabetes Care pmid:2507264
Lupinetti MD et al. Thromboxane biosynthesis in allergen-induced bronchospasm. Evidence for platelet activation. 1989 Am. Rev. Respir. Dis. pmid:2508524
Vesterqvist O and Gréen K Effects of naproxen on the in vivo synthesis of thromboxane and prostacyclin in man. 1989 Eur. J. Clin. Pharmacol. pmid:2515064
Beckmann ML et al. Prostacyclin synthesis is increased during propranolol therapy for essential hypertension. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526468
Knapp HR and Salem N Formation of PGI3 in the rat during dietary fish oil supplementation. 1989 Prostaglandins pmid:2557651
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Ritter JM et al. Differential effect of aspirin on thromboxane and prostaglandin biosynthesis in man. 1989 Br J Clin Pharmacol pmid:2590611
Chiabrando C et al. Quantitative profiling of 6-ketoprostaglandin F1 alpha, 2,3-dinor-6-ketoprostaglandin F1 alpha, thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine by immunoaffinity extraction with gas chromatography-mass spectrometry. 1989 J. Chromatogr. pmid:2613794
Förstermann U et al. An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A. 1989 Prostaglandins pmid:2662262
Grèen K et al. Pronounced reduction of in vivo prostacyclin synthesis in humans by acetaminophen (paracetamol). 1989 Prostaglandins pmid:2664901
Rousson D et al. Increased in vivo biosynthesis of prostacyclin and thromboxane A2 in chronic idiopathic thrombocytopenic purpura. 1989 Br. J. Haematol. pmid:2669929
Kühl PG et al. Endogenous formation of prostanoids in neonates with persistent pulmonary hypertension. 1989 Arch. Dis. Child. pmid:2673060
Barrow SE et al. Cigarette smoking: profiles of thromboxane- and prostacyclin-derived products in human urine. 1989 Biochim. Biophys. Acta pmid:2679889
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Aitokallio-Tallberg A et al. Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment. 1989 Br. J. Cancer pmid:2803956
Gréen K et al. Deficient prostacyclin formation after acute myocardial infarction. 1987 Lancet pmid:2883378
Edlund A et al. Myocardial ischaemia triggers formation of thromboxane. 1987 Lancet pmid:2887865
Fischer C and Meese CO Simultaneous determination of 6-oxo-prostaglandin F1 alpha and 2,3-dinor-6-oxo-prostaglandin F1 alpha in biological fluids by stable isotope dilution and negative ion chemical ionization mass spectrometry. 1985 Biomed. Mass Spectrom. pmid:2931130
Reilly IA et al. Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase. 1986 Circulation pmid:2938849
Gréen K and Vesterqvist O In vivo synthesis of thromboxane and prostacyclin in man in health and disease. Data from GC-MS measurements of major urinary metabolites. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949557
Gréen K and Vesterqvist O In vivo synthesis of thromboxane A2 and prostaglandin I2 in healthy and diseased individuals. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959096
Edlund A et al. Leg exercise increases prostacyclin synthesis without activating platelets in both healthy and atherosclerotic humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959097
Ciabattoni G et al. Radioimmunoassay measurement of 2,3-dinor metabolites of prostacyclin and thromboxane in human urine. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960163
Castagnoli MN et al. Combined high-performance liquid chromatography and enzyme immunoassay for the determination of urinary metabolites of thromboxane and 6-keto-PGF1 alpha. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960164
Ylikorkala O et al. Desogestrel- and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density lipoproteins. 1987 J. Clin. Endocrinol. Metab. pmid:2960690
Knapp HR et al. In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. 1986 N. Engl. J. Med. pmid:3007982
Balazy M et al. Facile method for preparation of 2,3-dinor-6-keto PGF1 alpha, the major urinary metabolite of prostacyclin. 1988 Prostaglandins pmid:3070630