2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Tibial Fractures D013978 4 associated lipids
Thrombosis D013927 49 associated lipids
Endometriosis D004715 29 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Per page 10 20 50 | Total 25

NCBI Entrez Crosslinks

All references with 2,3-dinor, 6-keto-PGF1alpha

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Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
Ross S et al. Association of cyclooxygenase-2 genetic variant with cardiovascular disease. 2014 Eur. Heart J. pmid:24796340
Skarke C et al. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. 2012 Clin. Pharmacol. Ther. pmid:22278334
Song WL et al. Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. 2012 J. Clin. Invest. pmid:22406532
Lynch CM et al. The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy. 2011 Prostaglandins Other Lipid Mediat. pmid:21723954
Yuhki K et al. [Prostaglandin I2 and its metabolites]. 2010 Nippon Rinsho pmid:20960743
Blatnik M and Steenwyk RC Quantification of urinary PGEm, 6-keto PGF(1alpha) and 2,3-dinor-6-keto PGF(1alpha) by UFLC-MS/MS before and after exercise. 2010 Prostaglandins Other Lipid Mediat. pmid:20416393
Fukushima H et al. Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. 2010 Am. J. Med. Genet. A pmid:20583254
Foudi N et al. Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation. 2009 Cardiovasc. Res. pmid:18952694
Zhao L et al. Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. 2009 Br. J. Pharmacol. pmid:19220291
Foudi N et al. Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits. 2009 Am. J. Physiol. Heart Circ. Physiol. pmid:19783781
Signore C et al. Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day. 2008 Alcohol. Clin. Exp. Res. pmid:18715278
Arnaud J et al. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites. 2007 J Am Coll Nutr pmid:17914127
Schwartz JI et al. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. 2007 J Clin Pharmacol pmid:17925592
Capone ML et al. Human pharmacology of naproxen sodium. 2007 J. Pharmacol. Exp. Ther. pmid:17473175
Stergioulas AT and Filippou DK Effects of physical conditioning on lipids and arachidonic acid metabolites in untrained boys: a longitudinal study. 2006 Appl Physiol Nutr Metab pmid:16900233
Stichtenoth DO et al. Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. 2005 Kidney Int. pmid:16221219
Saloheimo P et al. Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage. 2005 Thromb. Res. pmid:15733969
Hashimoto K et al. Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness. 2004 J. Virol. pmid:15367596
Vainio M et al. Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders. 2004 Acta Obstet Gynecol Scand pmid:15548142
Capone ML et al. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects. 2004 Circulation pmid:15037526
Mastrogiannis DS et al. Cocaine decreases urinary prostacyclin release in pregnancy: correlation with uterine and umbilical Doppler velocimetry. 2003 J. Matern. Fetal. Neonatal. Med. pmid:15061316
Saareks V et al. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man. 2002 Pharmacol. Toxicol. pmid:12403056
Kudolo GB et al. Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects. 2002 Thromb. Res. pmid:12590952
Sinzinger H Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications". 2002 Prostaglandins Leukot. Essent. Fatty Acids pmid:12445490
Stichtenoth DO et al. Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728174
Praticò D et al. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11248083
Hishinuma T et al. Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728171
Kaaja R et al. Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins. 2001 Br. J. Haematol. pmid:11552994
Dowd NP et al. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. 2001 J. Clin. Invest. pmid:11518732
Belton O et al. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis. 2000 Circulation pmid:10952950
Numminen H et al. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation. 2000 Stroke pmid:10835443
Delemarre FM et al. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11049696
Brown NJ et al. Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway. 2000 Circulation pmid:11056091
Tsikas D et al. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. 2000 J Chromatogr A pmid:10941682
McAdam BF et al. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:9874808
Morrow JD et al. Increased formation of thromboxane in vivo in humans with mastocytosis. 1999 J. Invest. Dermatol. pmid:10417625
Catella-Lawson F et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. 1999 J. Pharmacol. Exp. Ther. pmid:10215647
Barden AE et al. Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia? 1999 J. Hypertens. pmid:10489109
Mills JL et al. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study. 1999 JAMA pmid:10432033
Arvola P et al. Exercise enhances vasorelaxation in experimental obesity associated hypertension. 1999 Cardiovasc. Res. pmid:10615427
Tanaka H et al. Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A2 receptor antagonist in asthmatic patients? 1999 Respir Med pmid:10653051
Mizugaki M et al. Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method. 1999 Prostaglandins Other Lipid Mediat. pmid:10593167
Hishinuma T et al. Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic. 1999 Prostaglandins Other Lipid Mediat. pmid:10593168
Hoch B and Bernhard M Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants. 1999 Prostaglandins Other Lipid Mediat. pmid:10593170
Regan CL et al. Reduced fetal exposure to aspirin using a novel controlled-release preparation in normotensive and hypertensive pregnancies. 1998 Br J Obstet Gynaecol pmid:9692413
Lindström T et al. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures. 1998 J Trauma pmid:9783614
Moutquin JM et al. Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study. 1997 Am. J. Obstet. Gynecol. pmid:9423755
Rossi P et al. Percutaneous transluminal angioplasty increases thromboxane A2 production in claudicants. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9175173
Rautanen M et al. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs. 1997 Crit. Care Med. pmid:9233750
Farker K et al. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women. 1997 Prostaglandins pmid:9373880