2,3-dinor, 6-keto-PGF1alpha

2,3-dinor, 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 782 references associated with 2,3-dinor, 6-keto-PGF1alpha in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,3-dinor, 6-keto-PGF1alpha

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,3-dinor, 6-keto-PGF1alpha

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Body Weight D001835 333 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Tibial Fractures D013978 4 associated lipids
Thrombosis D013927 49 associated lipids
Endometriosis D004715 29 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Per page 10 20 50 | Total 25

NCBI Entrez Crosslinks

All references with 2,3-dinor, 6-keto-PGF1alpha

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Per page 10 20 50 100 | Total 191
Authors Title Published Journal PubMed Link
Zhao L et al. Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. 2009 Br. J. Pharmacol. pmid:19220291
Ward PS et al. Excretion of metabolites of prostacyclin and thromboxane by rats with nephrotoxic nephritis: effects of interleukin-1. 1991 Br. J. Pharmacol. pmid:1933130
Greer IA et al. Synergistic inhibitory effects of adrenoceptor antagonists and prostacyclin, and umbilical artery-derived prostacyclin-like activity on platelet aggregation. 1990 May-Jun Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:1970789
Foudi N et al. Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits. 2009 Am. J. Physiol. Heart Circ. Physiol. pmid:19783781
Rasmanis G et al. Prostacyclin production in myocardial infarction in the acute phase and during follow-up. 1991 J. Intern. Med. pmid:1997639
Wennmalm A et al. Relation between tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in young men. 1991 Circulation pmid:2022025
Blatnik M and Steenwyk RC Quantification of urinary PGEm, 6-keto PGF(1alpha) and 2,3-dinor-6-keto PGF(1alpha) by UFLC-MS/MS before and after exercise. 2010 Prostaglandins Other Lipid Mediat. pmid:20416393
Vernon WB Prostaglandins and pancreas transplantation. 1991 Prostaglandins pmid:2052737
Hotter G et al. Altered levels of tissue and urinary prostacyclin in rats subjected to pancreas transplantation. 1991 Prostaglandins pmid:2052738
Fukushima H et al. Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin. 2010 Am. J. Med. Genet. A pmid:20583254
Yuhki K et al. [Prostaglandin I2 and its metabolites]. 2010 Nippon Rinsho pmid:20960743
Ylikorkala O et al. Urinary excretion of prostacyclin and thromboxane metabolites in climacteric women: effect of estrogen-progestin replacement therapy. 1990 Prostaglandins pmid:2106714
Henriksson P et al. Thromboxane synthase inhibition: "endoperoxide shunt phenomenon" does not occur in healthy humans in vivo. 1990 Prostaglandins pmid:2106716
Edlund A et al. Acipimox stimulates skin blood flow by a cyclo-oxygenase-dependent mechanism. 1990 Eur. J. Clin. Pharmacol. pmid:2125938
Piret A et al. Increased platelet aggregability and prostacyclin biosynthesis induced by intense physical exercise. 1990 Thromb. Res. pmid:2140206
Lynch CM et al. The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy. 2011 Prostaglandins Other Lipid Mediat. pmid:21723954
Wennmalm A et al. Non-invasive assessment of the cardiovascular eicosanoids, thromboxane A2 and prostacyclin, in randomly sampled males, with special reference to the influence of inheritance and environmental factors. 1990 Clin. Sci. pmid:2176952
Skarke C et al. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. 2012 Clin. Pharmacol. Ther. pmid:22278334
Song WL et al. Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. 2012 J. Clin. Invest. pmid:22406532
pmid:24671522
Ross S et al. Association of cyclooxygenase-2 genetic variant with cardiovascular disease. 2014 Eur. Heart J. pmid:24796340
Hamazaki T et al. Urinary excretion of PGI2/3-M and recent N-6/3 fatty acid intake. 1989 Prostaglandins pmid:2503856
Ruth V et al. Urinary excretion of prostacyclin metabolites in infants born after maternal preeclampsia or with birth asphyxia. 1989 Biol. Neonate pmid:2506939
Koivisto VA et al. Stimulation of prostacyclin synthesis by physical exercise in type I diabetes. 1989 Diabetes Care pmid:2507264
Lupinetti MD et al. Thromboxane biosynthesis in allergen-induced bronchospasm. Evidence for platelet activation. 1989 Am. Rev. Respir. Dis. pmid:2508524
Vesterqvist O and Gréen K Effects of naproxen on the in vivo synthesis of thromboxane and prostacyclin in man. 1989 Eur. J. Clin. Pharmacol. pmid:2515064
Beckmann ML et al. Prostacyclin synthesis is increased during propranolol therapy for essential hypertension. 1989 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2526468
Knapp HR and Salem N Formation of PGI3 in the rat during dietary fish oil supplementation. 1989 Prostaglandins pmid:2557651
pmid:25669623
Ritter JM et al. Differential effect of aspirin on thromboxane and prostaglandin biosynthesis in man. 1989 Br J Clin Pharmacol pmid:2590611
Chiabrando C et al. Quantitative profiling of 6-ketoprostaglandin F1 alpha, 2,3-dinor-6-ketoprostaglandin F1 alpha, thromboxane B2 and 2,3-dinor-thromboxane B2 in human and rat urine by immunoaffinity extraction with gas chromatography-mass spectrometry. 1989 J. Chromatogr. pmid:2613794
Förstermann U et al. An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A. 1989 Prostaglandins pmid:2662262
Grèen K et al. Pronounced reduction of in vivo prostacyclin synthesis in humans by acetaminophen (paracetamol). 1989 Prostaglandins pmid:2664901
Rousson D et al. Increased in vivo biosynthesis of prostacyclin and thromboxane A2 in chronic idiopathic thrombocytopenic purpura. 1989 Br. J. Haematol. pmid:2669929
Kühl PG et al. Endogenous formation of prostanoids in neonates with persistent pulmonary hypertension. 1989 Arch. Dis. Child. pmid:2673060
Barrow SE et al. Cigarette smoking: profiles of thromboxane- and prostacyclin-derived products in human urine. 1989 Biochim. Biophys. Acta pmid:2679889
pmid:27137142
Aitokallio-Tallberg A et al. Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment. 1989 Br. J. Cancer pmid:2803956
Gréen K et al. Deficient prostacyclin formation after acute myocardial infarction. 1987 Lancet pmid:2883378
Edlund A et al. Myocardial ischaemia triggers formation of thromboxane. 1987 Lancet pmid:2887865
Fischer C and Meese CO Simultaneous determination of 6-oxo-prostaglandin F1 alpha and 2,3-dinor-6-oxo-prostaglandin F1 alpha in biological fluids by stable isotope dilution and negative ion chemical ionization mass spectrometry. 1985 Biomed. Mass Spectrom. pmid:2931130
Reilly IA et al. Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase. 1986 Circulation pmid:2938849
Gréen K and Vesterqvist O In vivo synthesis of thromboxane and prostacyclin in man in health and disease. Data from GC-MS measurements of major urinary metabolites. 1986 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2949557
Gréen K and Vesterqvist O In vivo synthesis of thromboxane A2 and prostaglandin I2 in healthy and diseased individuals. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959096
Edlund A et al. Leg exercise increases prostacyclin synthesis without activating platelets in both healthy and atherosclerotic humans. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2959097
Ciabattoni G et al. Radioimmunoassay measurement of 2,3-dinor metabolites of prostacyclin and thromboxane in human urine. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960163
Castagnoli MN et al. Combined high-performance liquid chromatography and enzyme immunoassay for the determination of urinary metabolites of thromboxane and 6-keto-PGF1 alpha. 1987 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:2960164
Ylikorkala O et al. Desogestrel- and levonorgestrel-containing oral contraceptives have different effects on urinary excretion of prostacyclin metabolites and serum high density lipoproteins. 1987 J. Clin. Endocrinol. Metab. pmid:2960690
Knapp HR et al. In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis. 1986 N. Engl. J. Med. pmid:3007982
Balazy M et al. Facile method for preparation of 2,3-dinor-6-keto PGF1 alpha, the major urinary metabolite of prostacyclin. 1988 Prostaglandins pmid:3070630