MeSH term | MeSH ID | Detail |
---|---|---|
Insulin Resistance | D007333 | 99 associated lipids |
Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Insulin Resistance | D007333 | 99 associated lipids |
Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
Lung Neoplasms | D008175 | 171 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ghali A et al. | Thrombocytopenic Purpura Associated with Dietary Supplements Containing Citrus Flavonoids. | Therapie | pmid:26242500 | |
pmid: | ||||
Kim H et al. | Induction of apoptosis in human cervical carcinoma HeLa cells by polymethoxylated flavone-rich Citrus grandis Osbeck (Dangyuja) leaf extract. | Food Chem. Toxicol. | pmid:20538032 | |
Mareel MM and De Mets M | Anti-invasive activities of experimental chemotherapeutic agents. | 1989 | Crit. Rev. Oncol. Hematol. | pmid:2686699 |
Bracke ME et al. | The flavonoid tangeretin inhibits invasion of MO4 mouse cells into embryonic chick heart in vitro. | 1989 May-Jun | Clin. Exp. Metastasis | pmid:2924447 |
Kandaswami C et al. | Antiproliferative effects of citrus flavonoids on a human squamous cell carcinoma in vitro. | 1991 | Cancer Lett. | pmid:1998943 |
Bracke M et al. | Effect of catechins and citrus flavonoids on invasion in vitro. | 1991 Jan-Feb | Clin. Exp. Metastasis | pmid:1901781 |
Kandaswami C et al. | Differential inhibition of proliferation of human squamous cell carcinoma, gliosarcoma and embryonic fibroblast-like lung cells in culture by plant flavonoids. | 1992 | Anticancer Drugs | pmid:1450447 |
Le Bon AM et al. | Inhibition of microsome-mediated binding of benzo[a]pyrene to DNA by flavonoids either in vitro or after dietary administration to rats. | 1992 | Chem. Biol. Interact. | pmid:1643669 |
Nguyen TD and Canada AT | Citrus flavonoids stimulate secretion by human colonic T84 cells. | 1993 | J. Nutr. | pmid:8381480 |