MeSH term | MeSH ID | Detail |
---|---|---|
Reperfusion Injury | D015427 | 65 associated lipids |
Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Reperfusion Injury | D015427 | 65 associated lipids |
Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nielsen SE et al. | Biotransformation of the citrus flavone tangeretin in rats. Identification of metabolites with intact flavane nucleus. | 2000 | Food Chem. Toxicol. | pmid:10930694 |
Wan J et al. | Enhancement of physical stability and bioaccessibility of tangeretin by soy protein isolate addition. | 2017 | Food Chem | pmid:27979270 |
Chen J et al. | Tangeretin-loaded protein nanoparticles fabricated from zein/β-lactoglobulin: preparation, characterization, and functional performance. | 2014 | Food Chem | pmid:24731371 |
Han S et al. | Simultaneous determination of polymethoxyflavones in Citrus species, Kiyomi tangor and Satsuma mandarin, by high performance liquid chromatography. | 2012 | Food Chem | pmid:23107751 |
Chen ZT et al. | Protective effects of sweet orange (Citrus sinensis) peel and their bioactive compounds on oxidative stress. | 2012 | Food Chem | pmid:22980779 |
Yang EJ et al. | Identification of active compounds from Aurantii Immatri Pericarpium attenuating brain injury in a rat model of ischemia-reperfusion. | 2013 | Food Chem | pmid:23265538 |
Jiang Y et al. | Stimulation effect of wide type CFTR chloride channel by the naturally occurring flavonoid tangeretin. | 2014 | Fitoterapia | pmid:25451794 |
Van Slambrouck S et al. | Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylation. | 2005 | FEBS Lett. | pmid:15757658 |
Lee DH et al. | Flavonoids Isolated from Korea Citrus aurantium L. Induce G2/M Phase Arrest and Apoptosis in Human Gastric Cancer AGS Cells. | 2012 | Evid Based Complement Alternat Med | pmid:22194772 |
Seo J et al. | Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation. | 2011 | Eur. J. Pharmacol. | pmid:22040922 |