MeSH term | MeSH ID | Detail |
---|---|---|
Reperfusion Injury | D015427 | 65 associated lipids |
Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Reperfusion Injury | D015427 | 65 associated lipids |
Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kou G et al. | Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance. | 2018 | J. Agric. Food Chem. | pmid:30369237 |
Obermeier MT et al. | Effects of bioflavonoids on hepatic P450 activities. | 1995 | Xenobiotica | pmid:7483658 |
Chaumontet C et al. | Apigenin and tangeretin enhance gap junctional intercellular communication in rat liver epithelial cells. | 1994 | Carcinogenesis | pmid:7955073 |
Nguyen TD and Canada AT | Citrus flavonoids stimulate secretion by human colonic T84 cells. | 1993 | J. Nutr. | pmid:8381480 |
Canivenc-Lavier MC et al. | Evidence for tangeretin O-demethylation by rat and human liver microsomes. | 1993 | Xenobiotica | pmid:8498088 |
Hirano T et al. | Citrus flavone tangeretin inhibits leukaemic HL-60 cell growth partially through induction of apoptosis with less cytotoxicity on normal lymphocytes. | 1995 | Br. J. Cancer | pmid:8519648 |
Canivenc-Lavier MC et al. | Differential effects of nonhydroxylated flavonoids as inducers of cytochrome P450 1A and 2B isozymes in rat liver. | 1996 | Toxicol. Appl. Pharmacol. | pmid:8619243 |
Calomme M et al. | Inhibition of bacterial mutagenesis by Citrus flavonoids. | 1996 | Planta Med. | pmid:8693033 |
Bracke ME et al. | The E-cadherin/catenin complex in invasion and metastasis. | 1996 | Curr. Top. Microbiol. Immunol. | pmid:8814984 |
Chaumontet C et al. | Lack of tumor-promoting effects of flavonoids: studies on rat liver preneoplastic foci and on in vivo and in vitro gap junctional intercellular communication. | 1996 | Nutr Cancer | pmid:8910908 |