MeSH term | MeSH ID | Detail |
---|---|---|
Reperfusion Injury | D015427 | 65 associated lipids |
Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Reperfusion Injury | D015427 | 65 associated lipids |
Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wan J et al. | Enhancement of physical stability and bioaccessibility of tangeretin by soy protein isolate addition. | 2017 | Food Chem | pmid:27979270 |
Fatima A et al. | Protective effect of tangeritin in transgenic Drosophila model of Parkinson's disease. | 2017 | Front Biosci (Elite Ed) | pmid:27814588 |
Eun SH et al. | Tangeretin Inhibits IL-12 Expression and NF-κB Activation in Dendritic Cells and Attenuates Colitis in Mice. | 2017 | Planta Med. | pmid:27806407 |
Arab HH et al. | Tangeretin attenuates cisplatin-induced renal injury in rats: Impact on the inflammatory cascade and oxidative perturbations. | 2016 | Chem. Biol. Interact. | pmid:27616468 |
Kuroda Y et al. | Activation of human bitter taste receptors by polymethoxylated flavonoids. | 2016 | Biosci. Biotechnol. Biochem. | pmid:27379685 |
Ma LL et al. | Tangeretin induces cell cycle arrest and apoptosis through upregulation of PTEN expression in glioma cells. | 2016 | Biomed. Pharmacother. | pmid:27261630 |
Funaro A et al. | Enhanced Anti-Inflammatory Activities by the Combination of Luteolin and Tangeretin. | 2016 | J. Food Sci. | pmid:27095513 |
Feng SL et al. | Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function. | 2016 | Pharmacol. Res. | pmid:27058921 |
Omar HA et al. | Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis. | 2016 | PLoS ONE | pmid:27031695 |
Hagenlocher Y et al. | Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. | 2017 | Eur J Nutr | pmid:27021766 |