MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
Diabetes Mellitus | D003920 | 90 associated lipids |
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
Diabetes Mellitus | D003920 | 90 associated lipids |
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Quintieri L et al. | Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes. | 2008 | Biochem. Pharmacol. | pmid:18191104 |
Wang Z et al. | Validated reversed phase LC method for quantitative analysis of polymethoxyflavones in citrus peel extracts. | 2008 | J Sep Sci | pmid:18095294 |
Satsu H et al. | Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals. | 2008 | J. Agric. Food Chem. | pmid:18540626 |
Miller EG et al. | Inhibition of oral carcinogenesis by citrus flavonoids. | 2008 | Nutr Cancer | pmid:18444138 |
Xu GH et al. | Minerals, phenolic compounds, and antioxidant capacity of citrus peel extract by hot water. | 2008 | J. Food Sci. | pmid:18211343 |
Walle UK and Walle T | Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones. | 2007 | Drug Metab. Dispos. | pmid:17709371 |
Johann S et al. | Antimicrobial activity of wax and hexane extracts from Citrus spp. peels. | 2007 | Mem. Inst. Oswaldo Cruz | pmid:17923995 |
Malemud CJ | Inhibitors of stress-activated protein/mitogen-activated protein kinase pathways. | 2007 | Curr Opin Pharmacol | pmid:17398158 |
Buisson D et al. | Biotransformation of polymethoxylated flavonoids: access to their 4'-O-demethylated metabolites. | 2007 | J. Nat. Prod. | pmid:17559266 |
Walle T | Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass? | 2007 | Semin. Cancer Biol. | pmid:17574860 |