MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Lake BG et al. | Inhibition of xenobiotic-induced genotoxicity in cultured precision-cut human and rat liver slices. | 1999 | Mutat. Res. | pmid:10095132 |
Rooprai HK et al. | Influence of putative antiinvasive agents on matrix metalloproteinase secretion by human neoplastic glia in vitro. | 1999 | Ann. N. Y. Acad. Sci. | pmid:10415799 |
Bracke ME et al. | Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer. | 1999 | J. Natl. Cancer Inst. | pmid:10050869 |
Breinholt V et al. | Differential effects of dietary flavonoids on drug metabolizing and antioxidant enzymes in female rat. | 1999 | Xenobiotica | pmid:10647909 |
Takanaga H et al. | Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10734174 |
Guo XL et al. | [Studies on chemical constituents of processed green tangerine peel]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12212096 |
Backman JT et al. | Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation. | 2000 | Clin. Pharmacol. Ther. | pmid:10801247 |
Depypere HT et al. | Inhibition of tamoxifen's therapeutic benefit by tangeretin in mammary cancer. | 2000 | Eur. J. Cancer | pmid:11056327 |
Ikegawa T et al. | Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells. | 2000 | Cancer Lett. | pmid:11098080 |
Siess MH et al. | Mechanisms involved in the chemoprevention of flavonoids. | 2000 | Biofactors | pmid:11216486 |