MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tangeretin
MeSH term | MeSH ID | Detail |
---|---|---|
Carcinoma, Non-Small-Cell Lung | D002289 | 72 associated lipids |
Atherosclerosis | D050197 | 85 associated lipids |
Insulin Resistance | D007333 | 99 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stroheker T et al. | Steroid activities comparison of natural and food wrap compounds in human breast cancer cell lines. | 2004 | Food Chem. Toxicol. | pmid:15110097 |
Kurowska EM et al. | Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, tangeretin. | 2004 | Lipids | pmid:15134141 |
Kurowska EM and Manthey JA | Hypolipidemic effects and absorption of citrus polymethoxylated flavones in hamsters with diet-induced hypercholesterolemia. | 2004 | J. Agric. Food Chem. | pmid:15137829 |
Yáñez J et al. | Cytotoxicity and antiproliferative activities of several phenolic compounds against three melanocytes cell lines: relationship between structure and activity. | 2004 | Nutr Cancer | pmid:15489212 |
Honda Y et al. | Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. | 2004 | Br. J. Pharmacol. | pmid:15504753 |
Liu L et al. | Phytochemical analysis of anti-atherogenic constituents of Xue-Fu-Zhu-Yu-Tang using HPLC-DAD-ESI-MS. | 2004 | Chem. Pharm. Bull. | pmid:15516749 |
Whitman SC et al. | Nobiletin, a citrus flavonoid isolated from tangerines, selectively inhibits class A scavenger receptor-mediated metabolism of acetylated LDL by mouse macrophages. | 2005 | Atherosclerosis | pmid:15585197 |
Van Slambrouck S et al. | Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylation. | 2005 | FEBS Lett. | pmid:15757658 |
Vanhoecke BW et al. | A safety study of oral tangeretin and xanthohumol administration to laboratory mice. | 2005 Jan-Feb | In Vivo | pmid:15796161 |
Mungur R et al. | Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. | 2005 | J. Biomed. Biotechnol. | pmid:16046826 |