Shi MD et al. |
Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells. |
2013 |
Phytomedicine |
pmid:23537747
|
Li ZH et al. |
[Determination of the active constituents in aurantii fructus from Jiangxi province at different harvest time by HPLC]. |
2013 |
Zhong Yao Cai |
pmid:23750404
|
Chong SY et al. |
Tangeretin sensitizes SGS1-deficient cells by inducing DNA damage. |
2013 |
J. Agric. Food Chem. |
pmid:23750935
|
Ting Y et al. |
Effect of a labile methyl donor on the transformation of 5-demethyltangeretin and the related implication on bioactivity. |
2013 |
J. Agric. Food Chem. |
pmid:23915315
|
Charoensinphon N et al. |
5-demethyltangeretin inhibits human nonsmall cell lung cancer cell growth by inducing G2/M cell cycle arrest and apoptosis. |
2013 |
Mol Nutr Food Res |
pmid:23926120
|
Jang SE et al. |
Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38. |
2013 |
Int. Immunopharmacol. |
pmid:23938254
|
Vaiyapuri S et al. |
Tangeretin regulates platelet function through inhibition of phosphoinositide 3-kinase and cyclic nucleotide signaling. |
2013 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:24135020
|
Lakshmi A and Subramanian S |
Chemotherapeutic effect of tangeretin, a polymethoxylated flavone studied in 7, 12-dimethylbenz(a)anthracene induced mammary carcinoma in experimental rats. |
2014 |
Biochimie |
pmid:24299963
|
Xu JJ et al. |
Antiviral activity of polymethoxylated flavones from "Guangchenpi", the edible and medicinal pericarps of citrus reticulata 'Chachi'. |
2014 |
J. Agric. Food Chem. |
pmid:24377463
|
Shu Z et al. |
Tangeretin exerts anti-neuroinflammatory effects via NF-κB modulation in lipopolysaccharide-stimulated microglial cells. |
2014 |
Int. Immunopharmacol. |
pmid:24462494
|
Dong Y et al. |
Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. |
2014 |
Oncol. Rep. |
pmid:24573532
|
Sundaram R et al. |
Effect of tangeretin, a polymethoxylated flavone on glucose metabolism in streptozotocin-induced diabetic rats. |
2014 |
Phytomedicine |
pmid:24629597
|
Chen J et al. |
Tangeretin-loaded protein nanoparticles fabricated from zein/β-lactoglobulin: preparation, characterization, and functional performance. |
2014 |
Food Chem |
pmid:24731371
|
Wang J et al. |
Pro-apoptotic effects of the novel tangeretin derivate 5-acetyl-6,7,8,4'-tetramethylnortangeretin on MCF-7 breast cancer cells. |
2014 |
Cell Biochem. Biophys. |
pmid:24938898
|
Ho SC and Kuo CT |
Hesperidin, nobiletin, and tangeretin are collectively responsible for the anti-neuroinflammatory capacity of tangerine peel (Citri reticulatae pericarpium). |
2014 |
Food Chem. Toxicol. |
pmid:24955543
|
Lakshmi A and Subramanian SP |
Tangeretin ameliorates oxidative stress in the renal tissues of rats with experimental breast cancer induced by 7,12-dimethylbenz[a]anthracene. |
2014 |
Toxicol. Lett. |
pmid:24995432
|
Arivazhagan L and Sorimuthu Pillai S |
Tangeretin, a citrus pentamethoxyflavone, exerts cytostatic effect via p53/p21 up-regulation and suppresses metastasis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinoma. |
2014 |
J. Nutr. Biochem. |
pmid:25151216
|
Aslan E and Adem S |
In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
pmid:25388478
|
Periyasamy K et al. |
Antitumor efficacy of tangeretin by targeting the oxidative stress mediated on 7,12-dimethylbenz(a) anthracene-induced proliferative breast cancer in Sprague-Dawley rats. |
2015 |
Cancer Chemother. Pharmacol. |
pmid:25431347
|
Jiang Y et al. |
Stimulation effect of wide type CFTR chloride channel by the naturally occurring flavonoid tangeretin. |
2014 |
Fitoterapia |
pmid:25451794
|
Das A et al. |
A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway. |
2015 |
Tumour Biol. |
pmid:25864108
|
Ting Y et al. |
Viscoelastic Emulsion Improved the Bioaccessibility and Oral Bioavailability of Crystalline Compound: A Mechanistic Study Using in Vitro and in Vivo Models. |
2015 |
Mol. Pharm. |
pmid:25984595
|
Zhang X et al. |
Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. |
2015 |
Oncol. Rep. |
pmid:25998143
|
Choi BK et al. |
A polymethoxy flavonoids-rich Citrus aurantium extract ameliorates ethanol-induced liver injury through modulation of AMPK and Nrf2-related signals in a binge drinking mouse model. |
2015 |
Phytother Res |
pmid:26178909
|
Ghali A et al. |
Thrombocytopenic Purpura Associated with Dietary Supplements Containing Citrus Flavonoids. |
|
Therapie |
pmid:26242500
|
Xu JJ et al. |
Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. |
2015 |
J. Agric. Food Chem. |
pmid:26468759
|
He YF et al. |
Tangeritin inhibits adipogenesis by down-regulating C/EBPα, C/EBPβ, and PPARγ expression in 3T3-L1 fat cells. |
2015 |
Genet. Mol. Res. |
pmid:26535679
|
Li YR et al. |
Tangeretin derivative, 5-acetyloxy-6,7,8,4'-tetramethoxyflavone induces G2/M arrest, apoptosis and autophagy in human non-small cell lung cancer cells in vitro and in vivo. |
2016 |
Cancer Biol. Ther. |
pmid:26569090
|
Sawadogo WR et al. |
Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3',4',5'-Pentamethoxyflavone Isolated from Lantana ukambensis. |
2015 |
Nutrients |
pmid:26690473
|
Mareel MM and De Mets M |
Anti-invasive activities of experimental chemotherapeutic agents. |
1989 |
Crit. Rev. Oncol. Hematol. |
pmid:2686699
|
Lee YY et al. |
Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia. |
2016 |
J Neuroimmune Pharmacol |
pmid:26899309
|
Batenburg AM et al. |
Characterization and Modulation of the Bitterness of Polymethoxyflavones Using Sensory and Receptor-Based Methods. |
2016 |
J. Agric. Food Chem. |
pmid:26934534
|
Hagenlocher Y et al. |
Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. |
2017 |
Eur J Nutr |
pmid:27021766
|
Omar HA et al. |
Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis. |
2016 |
PLoS ONE |
pmid:27031695
|
Feng SL et al. |
Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function. |
2016 |
Pharmacol. Res. |
pmid:27058921
|
Funaro A et al. |
Enhanced Anti-Inflammatory Activities by the Combination of Luteolin and Tangeretin. |
2016 |
J. Food Sci. |
pmid:27095513
|
Ma LL et al. |
Tangeretin induces cell cycle arrest and apoptosis through upregulation of PTEN expression in glioma cells. |
2016 |
Biomed. Pharmacother. |
pmid:27261630
|
Kuroda Y et al. |
Activation of human bitter taste receptors by polymethoxylated flavonoids. |
2016 |
Biosci. Biotechnol. Biochem. |
pmid:27379685
|
Arab HH et al. |
Tangeretin attenuates cisplatin-induced renal injury in rats: Impact on the inflammatory cascade and oxidative perturbations. |
2016 |
Chem. Biol. Interact. |
pmid:27616468
|
Eun SH et al. |
Tangeretin Inhibits IL-12 Expression and NF-κB Activation in Dendritic Cells and Attenuates Colitis in Mice. |
2017 |
Planta Med. |
pmid:27806407
|
Fatima A et al. |
Protective effect of tangeritin in transgenic Drosophila model of Parkinson's disease. |
2017 |
Front Biosci (Elite Ed) |
pmid:27814588
|
Wan J et al. |
Enhancement of physical stability and bioaccessibility of tangeretin by soy protein isolate addition. |
2017 |
Food Chem |
pmid:27979270
|
Johnson EJ et al. |
Prioritizing pharmacokinetic drug interaction precipitants in natural products: application to OATP inhibitors in grapefruit juice. |
2017 |
Biopharm Drug Dispos |
pmid:28032362
|
Braidy N et al. |
Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer's and Parkinson's Disease. |
2017 |
CNS Neurol Disord Drug Targets |
pmid:28474543
|
Guo XQ et al. |
Tangeretin alters neuronal apoptosis and ameliorates the severity of seizures in experimental epilepsy-induced rats by modulating apoptotic protein expressions, regulating matrix metalloproteinases, and activating the PI3K/Akt cell survival pathway. |
2017 |
Adv Med Sci |
pmid:28501723
|
Zeng SL et al. |
Chemicalome and metabolome profiling of polymethoxylated flavonoids in Citri Reticulatae Pericarpium based on an integrated strategy combining background subtraction and modified mass defect filter in a Microsoft Excel Platform. |
2017 |
J Chromatogr A |
pmid:28619587
|
Yoshizaki N et al. |
A polymethoxyflavone mixture extracted from orange peels, mainly containing nobiletin, 3,3',4',5,6,7,8-heptamethoxyflavone and tangeretin, suppresses melanogenesis through the acidification of cell organelles, including melanosomes. |
2017 |
J. Dermatol. Sci. |
pmid:28629701
|
Liu LL et al. |
Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/Th17 cytokine balance in neonatal asthmatic mice. |
2017 |
Braz. J. Med. Biol. Res. |
pmid:28746467
|
Youn K et al. |
Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels. |
2017 |
Nutrients |
pmid:28869548
|
Yuan ZW et al. |
Role of tangeretin as a potential bioavailability enhancer for silybin: Pharmacokinetic and pharmacological studies. |
2018 |
Pharmacol. Res. |
pmid:28958806
|