Tangeretin

Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tangeretin?

Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tangeretin

MeSH term MeSH ID Detail
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Atherosclerosis D050197 85 associated lipids
Insulin Resistance D007333 99 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Tangeretin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tangeretin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tangeretin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tangeretin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tangeretin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tangeretin?

Mouse Model

Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).

Transgenic Model

Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tangeretin

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Authors Title Published Journal PubMed Link
Kim H et al. Induction of apoptosis in human cervical carcinoma HeLa cells by polymethoxylated flavone-rich Citrus grandis Osbeck (Dangyuja) leaf extract. Food Chem. Toxicol. pmid:20538032
Lin LW et al. [Study on the contents of flavonoids in Citrus reticulata 'Chachi' from various habitats and different collecting periods]. 2010 Zhong Yao Cai pmid:20575406
Han S et al. Isolation and identification of polymethoxyflavones from the hybrid Citrus, hallabong. 2010 J. Agric. Food Chem. pmid:20698540
Sun Y et al. Simultaneous determination of flavonoids in different parts of Citrus reticulata 'Chachi' fruit by high performance liquid chromatography-photodiode array detection. 2010 Molecules pmid:20714303
Cao H et al. Binding Citrus flavanones to human serum albumin: effect of structure on affinity. 2011 Mol. Biol. Rep. pmid:20878474
Adepoju G and Adeyemi T Evaluation of the effect of lime fruit juice on the anticoagulant effect of warfarin. 2010 J Young Pharm pmid:21042484
Yoon JH et al. Tangeretin reduces ultraviolet B (UVB)-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking mitogen-activated protein kinase (MAPK) activation and reactive oxygen species (ROS) generation. 2011 J. Agric. Food Chem. pmid:21126077
Manthey JA et al. Pharmacokinetic study of nobiletin and tangeretin in rat serum by high-performance liquid chromatography-electrospray ionization-mass spectrometry. 2011 J. Agric. Food Chem. pmid:21133365
Cheng Z et al. Tangeretin and its metabolite 4'-hydroxytetramethoxyflavone attenuate EGF-stimulated cell cycle progression in hepatocytes; role of inhibition at the level of mTOR/p70S6K. 2011 Br. J. Pharmacol. pmid:21198542
Miyata Y et al. Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids, nobiletin and tangeretin. 2011 Life Sci. pmid:21295043
Wu HY et al. Suppression of hepatitis B virus x protein-mediated tumorigenic effects by ursolic Acid. 2011 J. Agric. Food Chem. pmid:21314126
Mazzio EA et al. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. 2011 Int J Mol Sci pmid:21340000
Nichols LA et al. Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes. 2011 Lipids Health Dis pmid:21345233
Lin Y et al. Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion. 2011 J. Agric. Food Chem. pmid:21425871
Mulvihill EE et al. Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance. 2011 Diabetes pmid:21471511
Yang X et al. Inhibition of citral degradation by oil-in-water nanoemulsions combined with antioxidants. 2011 J. Agric. Food Chem. pmid:21517071
Ayala-Zavala JF et al. Antioxidant enrichment and antimicrobial protection of fresh-cut fruits using their own byproducts: looking for integral exploitation. 2010 J. Food Sci. pmid:21535513
Vila-Real H et al. Enzymatic Synthesis of the Flavone Glucosides, Prunin and Isoquercetin, and the Aglycones, Naringenin and Quercetin, with Selective α-L-Rhamnosidase and β-D-Glucosidase Activities of Naringinase. 2011 Enzyme Res pmid:21941631
Tistaert C et al. Quality control of Citri reticulatae pericarpium: exploratory analysis and discrimination. 2011 Anal. Chim. Acta pmid:21962354
Sumbul S et al. Role of phenolic compounds in peptic ulcer: An overview. 2011 J Pharm Bioallied Sci pmid:21966156