Tangeretin

Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tangeretin?

Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tangeretin

MeSH term MeSH ID Detail
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Atherosclerosis D050197 85 associated lipids
Insulin Resistance D007333 99 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tangeretin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tangeretin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tangeretin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tangeretin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tangeretin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tangeretin?

Mouse Model

Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).

Transgenic Model

Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tangeretin

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Authors Title Published Journal PubMed Link
Li ZH et al. [Determination of the active constituents in aurantii fructus from Jiangxi province at different harvest time by HPLC]. 2013 Zhong Yao Cai pmid:23750404
Chong SY et al. Tangeretin sensitizes SGS1-deficient cells by inducing DNA damage. 2013 J. Agric. Food Chem. pmid:23750935
Jang SE et al. Nobiletin and tangeretin ameliorate scratching behavior in mice by inhibiting the action of histamine and the activation of NF-κB, AP-1 and p38. 2013 Int. Immunopharmacol. pmid:23938254
Vaiyapuri S et al. Tangeretin regulates platelet function through inhibition of phosphoinositide 3-kinase and cyclic nucleotide signaling. 2013 Arterioscler. Thromb. Vasc. Biol. pmid:24135020
Kim GS et al. Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells. 2012 BMC Complement Altern Med pmid:22471389
Mulvihill EE and Huff MW Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation. 2012 PPAR Res pmid:22701469
Furukawa Y et al. Isolation and characterization of activators of ERK/MAPK from citrus plants. 2012 Int J Mol Sci pmid:22408427
Vauzour D Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. 2012 Oxid Med Cell Longev pmid:22701758
Meiyanto E et al. Natural products for cancer-targeted therapy: citrus flavonoids as potent chemopreventive agents. 2012 Asian Pac. J. Cancer Prev. pmid:22524801
Kostrzewa-Susłow E and Janeczko T Microbial transformations of 7-hydroxyflavanone. 2012 ScientificWorldJournal pmid:22654578