Tangeretin

Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tangeretin?

Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tangeretin

MeSH term MeSH ID Detail
Carcinoma, Ductal, Breast D018270 19 associated lipids
Thrombosis D013927 49 associated lipids
Parkinson Disease D010300 53 associated lipids
Reperfusion Injury D015427 65 associated lipids
Neuroblastoma D009447 66 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Tangeretin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tangeretin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tangeretin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tangeretin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Tangeretin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tangeretin?

Mouse Model

Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).

Transgenic Model

Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tangeretin

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Per page 10 20 50 100 | Total 222
Authors Title Published Journal PubMed Link
Zou GA et al. Flavonoids from the stems of Croton caudatus Geisel. var. tomentosus Hook. 2010 Molecules pmid:20335965
Sun Y et al. Simultaneous determination of flavonoids in different parts of Citrus reticulata 'Chachi' fruit by high performance liquid chromatography-photodiode array detection. 2010 Molecules pmid:20714303
Ting Y et al. Viscoelastic Emulsion Improved the Bioaccessibility and Oral Bioavailability of Crystalline Compound: A Mechanistic Study Using in Vitro and in Vivo Models. 2015 Mol. Pharm. pmid:25984595
Kim MS et al. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice. 2012 Mol. Cell. Endocrinol. pmid:22476082
Shih WL et al. Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model. 2013 Mol. Carcinog. pmid:22549898
Ujiki MB et al. Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. 2006 Mol. Cancer pmid:17196098
Cao H et al. Binding Citrus flavanones to human serum albumin: effect of structure on affinity. 2011 Mol. Biol. Rep. pmid:20878474
Charoensinphon N et al. 5-demethyltangeretin inhibits human nonsmall cell lung cancer cell growth by inducing G2/M cell cycle arrest and apoptosis. 2013 Mol Nutr Food Res pmid:23926120
Qiu P et al. Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells. 2010 Mol Nutr Food Res pmid:20397199
Lust S et al. The flavonoid tangeretin activates the unfolded protein response and synergizes with imatinib in the erythroleukemia cell line K562. 2010 Mol Nutr Food Res pmid:20077418