| MeSH term | MeSH ID | Detail |
|---|---|---|
| Atherosclerosis | D050197 | 85 associated lipids |
| Carcinoma, Ductal, Breast | D018270 | 19 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Parkinson Disease | D010300 | 53 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
Tangeretin
Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tangeretin?
Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tangeretin
PubChem Associated disorders and diseases
What pathways are associated with Tangeretin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tangeretin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tangeretin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Tangeretin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Tangeretin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tangeretin?
Mouse Model
Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).
Transgenic Model
Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tangeretin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Guo XL et al. | [Studies on chemical constituents of processed green tangerine peel]. | 2000 | Zhongguo Zhong Yao Za Zhi | pmid:12212096 |
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| Li LJ et al. | [Chemical constituents from roots of Platycodon grandiflorum]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17144467 |
| Li ZH et al. | [Determination of the active constituents in aurantii fructus from Jiangxi province at different harvest time by HPLC]. | 2013 | Zhong Yao Cai | pmid:23750404 |
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| Park YJ et al. | [6]-Gingerol induces cell cycle arrest and cell death of mutant p53-expressing pancreatic cancer cells. | 2006 | Yonsei Med. J. | pmid:17066513 |
| Canivenc-Lavier MC et al. | Evidence for tangeretin O-demethylation by rat and human liver microsomes. | 1993 | Xenobiotica | pmid:8498088 |
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| Surichan S et al. | Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1-mediated metabolism to the product 4' hydroxy tangeretin. | 2018 | Toxicol In Vitro | pmid:29626627 |
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| Shi MD et al. | Nobiletin attenuates metastasis via both ERK and PI3K/Akt pathways in HGF-treated liver cancer HepG2 cells. | 2013 | Phytomedicine | pmid:23537747 |
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| Zhang X et al. | Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. | 2015 | Oncol. Rep. | pmid:25998143 |
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| Rooprai HK et al. | Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behaviour of brain tumour cells in vitro. | 2001 | Neuropathol. Appl. Neurobiol. | pmid:11299000 |
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