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The Inhibitory Effect of Flavonoid Aglycones on the Metabolic Activity of CYP3A4 Enzyme. |
2018 |
Molecules |
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Surichan S et al. |
Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1-mediated metabolism to the product 4' hydroxy tangeretin. |
2018 |
Toxicol In Vitro |
pmid:29626627
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Liang F et al. |
Attenuation of tert-Butyl Hydroperoxide ( t-BHP)-Induced Oxidative Damage in HepG2 Cells by Tangeretin: Relevance of the Nrf2-ARE and MAPK Signaling Pathways. |
2018 |
J. Agric. Food Chem. |
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Chen F et al. |
Tangeretin inhibits high glucose-induced extracellular matrix accumulation in human glomerular mesangial cells. |
2018 |
Biomed. Pharmacother. |
pmid:29710524
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Guo R et al. |
Identifying potential quality markers of Xin-Su-Ning capsules acting on arrhythmia by integrating UHPLC-LTQ-Orbitrap, ADME prediction and network target analysis. |
2018 |
Phytomedicine |
pmid:29526583
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Kou G et al. |
Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance. |
2018 |
J. Agric. Food Chem. |
pmid:30369237
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Yumnam S et al. |
Identification of a novel biomarker in tangeretin‑induced cell death in AGS human gastric cancer cells. |
2018 |
Oncol. Rep. |
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Roshini A et al. |
pH-sensitive tangeretin-ZnO quantum dots exert apoptotic and anti-metastatic effects in metastatic lung cancer cell line. |
2018 |
Mater Sci Eng C Mater Biol Appl |
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Yamaguchi M et al. |
Effects of Cultivation Month and Genetic Background on Phenolic Content of Citrus tachibana Peel. |
2018 |
Biol. Pharm. Bull. |
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Yuan ZW et al. |
Role of tangeretin as a potential bioavailability enhancer for silybin: Pharmacokinetic and pharmacological studies. |
2018 |
Pharmacol. Res. |
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Wang M et al. |
Antioxidant Protection of Nobiletin, 5-Demethylnobiletin, Tangeretin, and 5-Demethyltangeretin from Citrus Peel in Saccharomyces cerevisiae. |
2018 |
J. Agric. Food Chem. |
pmid:29526093
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Liu LL et al. |
Tangeretin has anti-asthmatic effects via regulating PI3K and Notch signaling and modulating Th1/Th2/Th17 cytokine balance in neonatal asthmatic mice. |
2017 |
Braz. J. Med. Biol. Res. |
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Zeng SL et al. |
Chemicalome and metabolome profiling of polymethoxylated flavonoids in Citri Reticulatae Pericarpium based on an integrated strategy combining background subtraction and modified mass defect filter in a Microsoft Excel Platform. |
2017 |
J Chromatogr A |
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Johnson EJ et al. |
Prioritizing pharmacokinetic drug interaction precipitants in natural products: application to OATP inhibitors in grapefruit juice. |
2017 |
Biopharm Drug Dispos |
pmid:28032362
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Wan J et al. |
Enhancement of physical stability and bioaccessibility of tangeretin by soy protein isolate addition. |
2017 |
Food Chem |
pmid:27979270
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Eun SH et al. |
Tangeretin Inhibits IL-12 Expression and NF-κB Activation in Dendritic Cells and Attenuates Colitis in Mice. |
2017 |
Planta Med. |
pmid:27806407
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Youn K et al. |
Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels. |
2017 |
Nutrients |
pmid:28869548
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Yoshizaki N et al. |
A polymethoxyflavone mixture extracted from orange peels, mainly containing nobiletin, 3,3',4',5,6,7,8-heptamethoxyflavone and tangeretin, suppresses melanogenesis through the acidification of cell organelles, including melanosomes. |
2017 |
J. Dermatol. Sci. |
pmid:28629701
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Guo XQ et al. |
Tangeretin alters neuronal apoptosis and ameliorates the severity of seizures in experimental epilepsy-induced rats by modulating apoptotic protein expressions, regulating matrix metalloproteinases, and activating the PI3K/Akt cell survival pathway. |
2017 |
Adv Med Sci |
pmid:28501723
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Braidy N et al. |
Neuroprotective Effects of Citrus Fruit-Derived Flavonoids, Nobiletin and Tangeretin in Alzheimer's and Parkinson's Disease. |
2017 |
CNS Neurol Disord Drug Targets |
pmid:28474543
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Fatima A et al. |
Protective effect of tangeritin in transgenic Drosophila model of Parkinson's disease. |
2017 |
Front Biosci (Elite Ed) |
pmid:27814588
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Hagenlocher Y et al. |
Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. |
2017 |
Eur J Nutr |
pmid:27021766
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Kuroda Y et al. |
Activation of human bitter taste receptors by polymethoxylated flavonoids. |
2016 |
Biosci. Biotechnol. Biochem. |
pmid:27379685
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Ma LL et al. |
Tangeretin induces cell cycle arrest and apoptosis through upregulation of PTEN expression in glioma cells. |
2016 |
Biomed. Pharmacother. |
pmid:27261630
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Feng SL et al. |
Tangeretin, a citrus pentamethoxyflavone, antagonizes ABCB1-mediated multidrug resistance by inhibiting its transport function. |
2016 |
Pharmacol. Res. |
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Batenburg AM et al. |
Characterization and Modulation of the Bitterness of Polymethoxyflavones Using Sensory and Receptor-Based Methods. |
2016 |
J. Agric. Food Chem. |
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Anti-Inflammatory and Antioxidant Mechanism of Tangeretin in Activated Microglia. |
2016 |
J Neuroimmune Pharmacol |
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Li YR et al. |
Tangeretin derivative, 5-acetyloxy-6,7,8,4'-tetramethoxyflavone induces G2/M arrest, apoptosis and autophagy in human non-small cell lung cancer cells in vitro and in vivo. |
2016 |
Cancer Biol. Ther. |
pmid:26569090
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Funaro A et al. |
Enhanced Anti-Inflammatory Activities by the Combination of Luteolin and Tangeretin. |
2016 |
J. Food Sci. |
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Omar HA et al. |
Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis. |
2016 |
PLoS ONE |
pmid:27031695
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Tangeretin attenuates cisplatin-induced renal injury in rats: Impact on the inflammatory cascade and oxidative perturbations. |
2016 |
Chem. Biol. Interact. |
pmid:27616468
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Xu JJ et al. |
Tangeretin from Citrus reticulate Inhibits Respiratory Syncytial Virus Replication and Associated Inflammation in Vivo. |
2015 |
J. Agric. Food Chem. |
pmid:26468759
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Choi BK et al. |
A polymethoxy flavonoids-rich Citrus aurantium extract ameliorates ethanol-induced liver injury through modulation of AMPK and Nrf2-related signals in a binge drinking mouse model. |
2015 |
Phytother Res |
pmid:26178909
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Zhang X et al. |
Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells. |
2015 |
Oncol. Rep. |
pmid:25998143
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Das A et al. |
A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway. |
2015 |
Tumour Biol. |
pmid:25864108
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Periyasamy K et al. |
Antitumor efficacy of tangeretin by targeting the oxidative stress mediated on 7,12-dimethylbenz(a) anthracene-induced proliferative breast cancer in Sprague-Dawley rats. |
2015 |
Cancer Chemother. Pharmacol. |
pmid:25431347
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Aslan E and Adem S |
In vitro effects of some flavones on human pyruvate kinase isoenzyme M2. |
2015 |
J. Biochem. Mol. Toxicol. |
pmid:25388478
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Sawadogo WR et al. |
Cytotoxic, Antiproliferative and Pro-Apoptotic Effects of 5-Hydroxyl-6,7,3',4',5'-Pentamethoxyflavone Isolated from Lantana ukambensis. |
2015 |
Nutrients |
pmid:26690473
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Ting Y et al. |
Viscoelastic Emulsion Improved the Bioaccessibility and Oral Bioavailability of Crystalline Compound: A Mechanistic Study Using in Vitro and in Vivo Models. |
2015 |
Mol. Pharm. |
pmid:25984595
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He YF et al. |
Tangeritin inhibits adipogenesis by down-regulating C/EBPα, C/EBPβ, and PPARγ expression in 3T3-L1 fat cells. |
2015 |
Genet. Mol. Res. |
pmid:26535679
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Lakshmi A and Subramanian SP |
Tangeretin ameliorates oxidative stress in the renal tissues of rats with experimental breast cancer induced by 7,12-dimethylbenz[a]anthracene. |
2014 |
Toxicol. Lett. |
pmid:24995432
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Lakshmi A and Subramanian S |
Chemotherapeutic effect of tangeretin, a polymethoxylated flavone studied in 7, 12-dimethylbenz(a)anthracene induced mammary carcinoma in experimental rats. |
2014 |
Biochimie |
pmid:24299963
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Xu JJ et al. |
Antiviral activity of polymethoxylated flavones from "Guangchenpi", the edible and medicinal pericarps of citrus reticulata 'Chachi'. |
2014 |
J. Agric. Food Chem. |
pmid:24377463
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Dong Y et al. |
Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. |
2014 |
Oncol. Rep. |
pmid:24573532
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Jiang Y et al. |
Stimulation effect of wide type CFTR chloride channel by the naturally occurring flavonoid tangeretin. |
2014 |
Fitoterapia |
pmid:25451794
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Arivazhagan L and Sorimuthu Pillai S |
Tangeretin, a citrus pentamethoxyflavone, exerts cytostatic effect via p53/p21 up-regulation and suppresses metastasis in 7,12-dimethylbenz(α)anthracene-induced rat mammary carcinoma. |
2014 |
J. Nutr. Biochem. |
pmid:25151216
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Ho SC and Kuo CT |
Hesperidin, nobiletin, and tangeretin are collectively responsible for the anti-neuroinflammatory capacity of tangerine peel (Citri reticulatae pericarpium). |
2014 |
Food Chem. Toxicol. |
pmid:24955543
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Wang J et al. |
Pro-apoptotic effects of the novel tangeretin derivate 5-acetyl-6,7,8,4'-tetramethylnortangeretin on MCF-7 breast cancer cells. |
2014 |
Cell Biochem. Biophys. |
pmid:24938898
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Chen J et al. |
Tangeretin-loaded protein nanoparticles fabricated from zein/β-lactoglobulin: preparation, characterization, and functional performance. |
2014 |
Food Chem |
pmid:24731371
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Sundaram R et al. |
Effect of tangeretin, a polymethoxylated flavone on glucose metabolism in streptozotocin-induced diabetic rats. |
2014 |
Phytomedicine |
pmid:24629597
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