Tangeretin

Tangeretin is a lipid of Polyketides (PK) class. Tangeretin is associated with abnormalities such as Cardiovascular Diseases, Complex Regional Pain Syndromes, Blood Clot, Hypercholesterolemia and Restenosis. The involved functions are known as Thrombus, Platelet function, Localized desquamation, Platelet Activation and Signal. Tangeretin often locates in Protoplasm, Cytoplasmic Granules, Cytoplasmic matrix, Plasma membrane and Blood. The associated genes with Tangeretin are GP6 gene, CDK2 gene, CDK6 gene, Tumor Suppressor Genes and CDH1 gene. The related lipids are Lipopolysaccharides. The related experimental models are Mouse Model and Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of Tangeretin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tangeretin?

Tangeretin is suspected in Complex Regional Pain Syndromes, Cardiovascular Diseases, Blood Clot, Hypercholesterolemia, Restenosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tangeretin

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Lung Neoplasms D008175 171 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Carcinoma, Ductal, Breast D018270 19 associated lipids
Parkinson Disease D010300 53 associated lipids
Per page 10 20 | Total 13

PubChem Associated disorders and diseases

What pathways are associated with Tangeretin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tangeretin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Tangeretin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tangeretin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Tangeretin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tangeretin?

Mouse Model

Mouse Model are used in the study 'Methoxyflavones protect cells against endoplasmic reticulum stress and neurotoxin.' (Takano K et al., 2007) and Mouse Model are used in the study 'Influence of tangeretin on tamoxifen's therapeutic benefit in mammary cancer.' (Bracke ME et al., 1999).

Transgenic Model

Transgenic Model are used in the study 'Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?' (Walle T, 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with Tangeretin

Download all related citations
Per page 10 20 50 100 | Total 222
Authors Title Published Journal PubMed Link
Cao H et al. Binding Citrus flavanones to human serum albumin: effect of structure on affinity. 2011 Mol. Biol. Rep. pmid:20878474
Yang X et al. Inhibition of citral degradation by oil-in-water nanoemulsions combined with antioxidants. 2011 J. Agric. Food Chem. pmid:21517071
Mulvihill EE et al. Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance. 2011 Diabetes pmid:21471511
Kyselova Z Toxicological aspects of the use of phenolic compounds in disease prevention. 2011 Interdiscip Toxicol pmid:22319251
Sumbul S et al. Role of phenolic compounds in peptic ulcer: An overview. 2011 J Pharm Bioallied Sci pmid:21966156
Mazzio EA et al. The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. 2011 Int J Mol Sci pmid:21340000
Vila-Real H et al. Enzymatic Synthesis of the Flavone Glucosides, Prunin and Isoquercetin, and the Aglycones, Naringenin and Quercetin, with Selective α-L-Rhamnosidase and β-D-Glucosidase Activities of Naringinase. 2011 Enzyme Res pmid:21941631
Nichols LA et al. Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes. 2011 Lipids Health Dis pmid:21345233
Hazra B et al. The prospective role of plant products in radiotherapy of cancer: a current overview. 2011 Front Pharmacol pmid:22291649
Lin Y et al. Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion. 2011 J. Agric. Food Chem. pmid:21425871
Manthey JA et al. Pharmacokinetic study of nobiletin and tangeretin in rat serum by high-performance liquid chromatography-electrospray ionization-mass spectrometry. 2011 J. Agric. Food Chem. pmid:21133365
Yoon JH et al. Tangeretin reduces ultraviolet B (UVB)-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking mitogen-activated protein kinase (MAPK) activation and reactive oxygen species (ROS) generation. 2011 J. Agric. Food Chem. pmid:21126077
Miyata Y et al. Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids, nobiletin and tangeretin. 2011 Life Sci. pmid:21295043
Cheng Z et al. Tangeretin and its metabolite 4'-hydroxytetramethoxyflavone attenuate EGF-stimulated cell cycle progression in hepatocytes; role of inhibition at the level of mTOR/p70S6K. 2011 Br. J. Pharmacol. pmid:21198542
Wu HY et al. Suppression of hepatitis B virus x protein-mediated tumorigenic effects by ursolic Acid. 2011 J. Agric. Food Chem. pmid:21314126
Nakayama N et al. Extract from peel of Citrus natsudaidai alleviates experimental chronic allergic dermatitis in mice. 2011 Pharmacognosy Res pmid:22022162
Seo J et al. Tangeretin, a citrus flavonoid, inhibits PGDF-BB-induced proliferation and migration of aortic smooth muscle cells by blocking AKT activation. 2011 Eur. J. Pharmacol. pmid:22040922
Chahar MK et al. Flavonoids: A versatile source of anticancer drugs. 2011 Pharmacogn Rev pmid:22096313
Tistaert C et al. Quality control of Citri reticulatae pericarpium: exploratory analysis and discrimination. 2011 Anal. Chim. Acta pmid:21962354
Oshitari T et al. B-Ring-modified and/or 5-demethylated nobiletin congeners: inhibitory activity against pro-MMP-9 production. 2011 Bioorg. Med. Chem. pmid:22047798