ISOVALERIC ACID
ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ISOVALERIC ACID?
ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID
PubChem Associated disorders and diseases
What pathways are associated with ISOVALERIC ACID
Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ISOVALERIC ACID?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
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| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with ISOVALERIC ACID?
Knock-out
Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with ISOVALERIC ACID
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cloarec O et al. | Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets. | 2005 | Anal. Chem. | pmid:15732908 |
| Graça G et al. | Metabolite profiling of human amniotic fluid by hyphenated nuclear magnetic resonance spectroscopy. | 2008 | Anal. Chem. | pmid:18564856 |
| Maxia C et al. | A morphological and 13C NMR study of the extramandibular fat bodies of the striped dolphin (Stenella coeruleoalba). | 2007 | Anat Rec (Hoboken) | pmid:17516451 |
| Weng Y et al. | Isovaleric, methylmalonic, and propionic acid decrease anesthetic EC50 in tadpoles, modulate glycine receptor function, and interact with the lipid 1,2-dipalmitoyl-Sn-glycero-3-phosphocholine. | 2009 | Anesth. Analg. | pmid:19372333 |
| González LA et al. | Increasing sodium bicarbonate level in high-concentrate diets for heifers. I. Effects on intake, water consumption and ruminal fermentation. | 2008 | Animal | pmid:22443595 |
| Lynch MB et al. | Effects of increasing the intake of dietary β-glucans by exchanging wheat for barley on nutrient digestibility, nitrogen excretion, intestinal microflora, volatile fatty acid concentration and manure ammonia emissions in finishing pigs. | 2007 | Animal | pmid:22444744 |
| Røjen BA et al. | Urea and short-chain fatty acids metabolism in Holstein cows fed a low-nitrogen grass-based diet. | 2008 | Animal | pmid:22443564 |
| Getachew G et al. | Influence of tannic acid application on alfalfa hay: in vitro rumen fermentation, serum metabolites and nitrogen balance in sheep. | 2008 | Animal | pmid:22445040 |
| Iino Y et al. | Organic acids and anaerobic microorganisms in the contents of the cholesteatoma sac. | 1983 Jan-Feb | Ann. Otol. Rhinol. Laryngol. | pmid:6337545 |
| Candau M and Massengo J | Evidence of a thiamine deficiency in sheep fed maize silage. | 1982 | Ann. Rech. Vet. | pmid:7185321 |