ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.
To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID
Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Pathway name | Related literatures |
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Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Etchebehere C et al. | Comamonas nitrativorans sp. nov., a novel denitrifier isolated from a denitrifying reactor treating landfill leachate. | 2001 | Int. J. Syst. Evol. Microbiol. | pmid:11411724 |
Takahashi N and Sato T | Preferential utilization of dipeptides by Porphyromonas gingivalis. | 2001 | J. Dent. Res. | pmid:11437213 |
Hood CR and Randall AA | A biochemical hypothesis explaining the response of enhanced biological phosphorus removal biomass to organic substrates. | 2001 | Water Res. | pmid:11456176 |
Matsubara Y | [Acidemia, isovaleric]. | 2001 | Ryoikibetsu Shokogun Shirizu | pmid:11462734 |
Besong S et al. | Influence of supplemental chromium on concentrations of liver triglyceride, blood metabolites and rumen VFA profile in steers fed a moderately high fat diet. | 2001 | J. Dairy Sci. | pmid:11467818 |
Ruan Y et al. | Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized. | 2001 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11481456 |
Kim BC et al. | Thermoanaerobacter yonseiensis sp. nov., a novel extremely thermophilic, xylose-utilizing bacterium that grows at up to 85 degrees C. | 2001 | Int. J. Syst. Evol. Microbiol. | pmid:11491356 |
Kirchhoff E and Schieberle P | Determination of key aroma compounds in the crumb of a three-stage sourdough rye bread by stable isotope dilution assays and sensory studies. | 2001 | J. Agric. Food Chem. | pmid:11559129 |
Costantini C et al. | Electroantennogram and behavioural responses of the malaria vector Anopheles gambiae to human-specific sweat components. | 2001 | Med. Vet. Entomol. | pmid:11583442 |
Fang HH and Yu H | Mesophilic acidification of gelatinaceous wastewater. | 2002 | J. Biotechnol. | pmid:11738717 |