ISOVALERIC ACID

ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOVALERIC ACID?

ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID

MeSH term MeSH ID Detail
Cerebellar Diseases D002526 2 associated lipids
Cerebral Hemorrhage D002543 13 associated lipids
Hypoglycemia D007003 13 associated lipids
Bacteroides Infections D001442 1 associated lipids
Clostridium Infections D003015 5 associated lipids
Fusobacterium Infections D005674 3 associated lipids
Sepsis D018805 11 associated lipids
Thiamine Deficiency D013832 4 associated lipids
Pancytopenia D010198 6 associated lipids
Nervous System Diseases D009422 37 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with ISOVALERIC ACID

Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOVALERIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOVALERIC ACID?


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Function Cross reference Weighted score Related literatures

What lipids are associated with ISOVALERIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOVALERIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOVALERIC ACID?

Knock-out

Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOVALERIC ACID

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Authors Title Published Journal PubMed Link
Zhang X and Firestein S The olfactory receptor gene superfamily of the mouse. 2002 Nat. Neurosci. pmid:11802173
Thierry A et al. Conversion of L-leucine to isovaleric acid by Propionibacterium freudenreichii TL 34 and ITGP23. 2002 Appl. Environ. Microbiol. pmid:11823198
van Heugten E and van Kempen TA Growth performance, carcass characteristics, nutrient digestibility and fecal odorous compounds in growing-finishing pigs fed diets containing hydrolyzed feather meal. 2002 J. Anim. Sci. pmid:11833534
Menes RJ and Muxí L Anaerobaculum mobile sp. nov., a novel anaerobic, moderately thermophilic, peptide-fermenting bacterium that uses crotonate as an electron acceptor, and emended description of the genus Anaerobaculum. 2002 Int. J. Syst. Evol. Microbiol. pmid:11837298
Silva MF et al. Characterization of plasma acylcarnitines in patients under valproate monotherapy using ESI-MS/MS. 2001 Clin. Biochem. pmid:11849623
Nevalainen M and Koskinen AM Total synthesis of nor-1,6-germacradien-5-ols. 2002 J. Org. Chem. pmid:11871886
Aro T et al. Determination of semivolatile compounds in Baltic herring (Clupea harengus membras) by supercritical fluid extraction-supercritical fluid chromatography-gas chromatography-mass spectrometry. 2002 J. Agric. Food Chem. pmid:11902942
Zhou Q et al. Identification and quantification of aroma-active components that contribute to the distinct malty flavor of buckwheat honey. 2002 J. Agric. Food Chem. pmid:11902950
Schneider IC et al. Fermentation of cottonseed and other feedstuffs in cattle rumen fluid. 2002 J. Agric. Food Chem. pmid:11929282
Landy P et al. Sensory and chemical changes in tomato sauces during storage. 2002 J. Agric. Food Chem. pmid:12009996