| MeSH term | MeSH ID | Detail |
|---|---|---|
| Metabolic Diseases | D008659 | 12 associated lipids |
| Tyrosinemias | D020176 | 2 associated lipids |
| Propionic Acidemia | D056693 | 3 associated lipids |
| Gingivitis | D005891 | 3 associated lipids |
| Periodontal Pocket | D010514 | 9 associated lipids |
ISOVALERIC ACID
ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ISOVALERIC ACID?
ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID
PubChem Associated disorders and diseases
What pathways are associated with ISOVALERIC ACID
Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ISOVALERIC ACID?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with ISOVALERIC ACID?
Knock-out
Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with ISOVALERIC ACID
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pais VF et al. | An electronic nose based on coated piezoelectric quartz crystals to certify ewes' cheese and to discriminate between cheese varieties. | 2012 | Sensors (Basel) | pmid:22438717 |
| Qiqiang L et al. | Longitudinal study of volatile fatty acids in the gingival crevicular fluid of patients with periodontitis before and after nonsurgical therapy. | 2012 | J. Periodont. Res. | pmid:22594616 |
| Moura AP et al. | 3-Methylcrotonylglycine disrupts mitochondrial energy homeostasis and inhibits synaptic Na(+),K (+)-ATPase activity in brain of young rats. | 2012 | Cell. Mol. Neurobiol. | pmid:21993987 |
| Grégoire P et al. | Desulfosoma profundi sp. nov., a thermophilic sulfate-reducing bacterium isolated from a deep terrestrial geothermal spring in France. | 2012 | Antonie Van Leeuwenhoek | pmid:22120904 |
| Curtin CD et al. | De-novo assembly and analysis of the heterozygous triploid genome of the wine spoilage yeast Dekkera bruxellensis AWRI1499. | 2012 | PLoS ONE | pmid:22470482 |
| Can Güven S and Laska M | Olfactory sensitivity and odor structure-activity relationships for aliphatic carboxylic acids in CD-1 mice. | 2012 | PLoS ONE | pmid:22479594 |
| Bai G et al. | Comparison of storage conditions for human vaginal microbiome studies. | 2012 | PLoS ONE | pmid:22655031 |
| Kerr KR et al. | Apparent total tract energy and macronutrient digestibility and fecal fermentative end-product concentrations of domestic cats fed extruded, raw beef-based, and cooked beef-based diets. | 2012 | J. Anim. Sci. | pmid:22003235 |
| Kim YH and Kim KH | Novel approach to test the relative recovery of liquid-phase standard in sorbent-tube analysis of gaseous volatile organic compounds. | 2012 | Anal. Chem. | pmid:22468653 |
| Badenhorst CP et al. | Enzymatic characterization and elucidation of the catalytic mechanism of a recombinant bovine glycine N-acyltransferase. | 2012 | Drug Metab. Dispos. | pmid:22071172 |
| Bloomer RJ et al. | Effects of 2-nitrooxy ethyl 2-amino 3-methylbutanoate gel on resistance exercise performance and blood nitrate/nitrite in resistance trained men. | 2012 | J Strength Cond Res | pmid:21921823 |
| Fang JJ et al. | Odor compounds from different sources of landfill: characterization and source identification. | 2012 | Waste Manag | pmid:22480726 |
| Mohamed HN et al. | Tentative identification of volatile flavor compounds in commercial Budu, a Malaysian fish sauce, using GC-MS. | 2012 | Molecules | pmid:22555296 |
| Rughoonundun H et al. | Influence of carbon-to-nitrogen ratio on the mixed-acid fermentation of wastewater sludge and pretreated bagasse. | 2012 | Bioresour. Technol. | pmid:22425518 |
| Rehman A et al. | Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine. | 2012 | BMC Microbiol. | pmid:22452835 |
| Xiong M et al. | A bio-catalytic approach to aliphatic ketones. | 2012 | Sci Rep | pmid:22416247 |
| Sun JL et al. | Metabolic profiling of Staphylococcus aureus cultivated under aerobic and anaerobic conditions with (1)H NMR-based nontargeted analysis. | 2012 | Can. J. Microbiol. | pmid:22571732 |
| Walton GE et al. | A randomised, double-blind, placebo controlled cross-over study to determine the gastrointestinal effects of consumption of arabinoxylan-oligosaccharides enriched bread in healthy volunteers. | 2012 | Nutr J | pmid:22657950 |
| French EA et al. | Rumen and milk odd- and branched-chain fatty acid proportions are minimally influenced by ruminal volatile fatty acid infusions. | 2012 | J. Dairy Sci. | pmid:22459847 |
| Ni JQ et al. | Volatile organic compounds at swine facilities: a critical review. | 2012 | Chemosphere | pmid:22682363 |