ISOVALERIC ACID

ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOVALERIC ACID?

ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Occupational Diseases D009784 42 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Olfaction Disorders D000857 17 associated lipids
Maple Syrup Urine Disease D008375 5 associated lipids
Acidosis, Renal Tubular D000141 4 associated lipids
Fanconi Syndrome D005198 4 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Dwarfism D004392 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with ISOVALERIC ACID

Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOVALERIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOVALERIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with ISOVALERIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOVALERIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOVALERIC ACID?

Knock-out

Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOVALERIC ACID

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Authors Title Published Journal PubMed Link
Pais VF et al. An electronic nose based on coated piezoelectric quartz crystals to certify ewes' cheese and to discriminate between cheese varieties. 2012 Sensors (Basel) pmid:22438717
Moura AP et al. 3-Methylcrotonylglycine disrupts mitochondrial energy homeostasis and inhibits synaptic Na(+),K (+)-ATPase activity in brain of young rats. 2012 Cell. Mol. Neurobiol. pmid:21993987
Curtin CD et al. De-novo assembly and analysis of the heterozygous triploid genome of the wine spoilage yeast Dekkera bruxellensis AWRI1499. 2012 PLoS ONE pmid:22470482
Kerr KR et al. Apparent total tract energy and macronutrient digestibility and fecal fermentative end-product concentrations of domestic cats fed extruded, raw beef-based, and cooked beef-based diets. 2012 J. Anim. Sci. pmid:22003235
Kim YH and Kim KH Novel approach to test the relative recovery of liquid-phase standard in sorbent-tube analysis of gaseous volatile organic compounds. 2012 Anal. Chem. pmid:22468653
Rehman A et al. Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine. 2012 BMC Microbiol. pmid:22452835
French EA et al. Rumen and milk odd- and branched-chain fatty acid proportions are minimally influenced by ruminal volatile fatty acid infusions. 2012 J. Dairy Sci. pmid:22459847
Paczkowski S and Schütz S Post-mortem volatiles of vertebrate tissue. 2011 Appl. Microbiol. Biotechnol. pmid:21720824
Kumar PA et al. Identification of fruity aroma-producing compounds from Chryseobacterium sp. isolated from the Western Ghats, India. 2011 Curr. Microbiol. pmid:21667308
Serrazanetti DI et al. Acid stress-mediated metabolic shift in Lactobacillus sanfranciscensis LSCE1. 2011 Appl. Environ. Microbiol. pmid:21335381
Shank RA et al. Current and future experimental strategies for structural analysis of trichothecene mycotoxins--a prospectus. 2011 Toxins (Basel) pmid:22295175
Van Ziffle J et al. Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia. 2011 PLoS ONE pmid:21390308
Pelchat ML et al. Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. 2011 Chem. Senses pmid:20876394
Pati A et al. Non-contiguous finished genome sequence of the opportunistic oral pathogen Prevotella multisaccharivorax type strain (PPPA20). 2011 Stand Genomic Sci pmid:22180809
Arora R et al. Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud. 2011 Evid Based Complement Alternat Med pmid:20976081
Nes WD Biosynthesis of cholesterol and other sterols. 2011 Chem. Rev. pmid:21902244
Ensenauer R et al. Newborn screening for isovaleric acidemia using tandem mass spectrometry: data from 1.6 million newborns. 2011 Clin. Chem. pmid:21335445
Dinarvand R et al. Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents. 2011 Int J Nanomedicine pmid:21720501
Holzmann I et al. Evaluation of Behavioral and Pharmacological Effects of Hydroalcoholic Extract of Valeriana prionophylla Standl. from Guatemala. 2011 Evid Based Complement Alternat Med pmid:21754942
Gronow S et al. Complete genome sequence of Bacteroides salanitronis type strain (BL78). 2011 Stand Genomic Sci pmid:21677856
Zasloff M Observations on the remarkable (and mysterious) wound-healing process of the bottlenose dolphin. 2011 J. Invest. Dermatol. pmid:21776005
Hansen CF et al. A high dietary concentration of inulin is necessary to reduce the incidence of swine dysentery in pigs experimentally challenged with Brachyspira hyodysenteriae. 2011 Br. J. Nutr. pmid:21736788
Chin ST et al. Identification of potent odourants in wine and brewed coffee using gas chromatography-olfactometry and comprehensive two-dimensional gas chromatography. 2011 J Chromatogr A pmid:21741655
Weickert MO et al. Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity. 2011 Nutr Metab (Lond) pmid:22177085
Kashima Y et al. Insecticidal effect and chemical composition of the volatile oil from Bergenia ligulata. 2011 J. Agric. Food Chem. pmid:21639116
Aguerre MJ et al. Effect of forage-to-concentrate ratio in dairy cow diets on emission of methane, carbon dioxide, and ammonia, lactation performance, and manure excretion. 2011 J. Dairy Sci. pmid:21605777
Prakash S et al. Gut microbiota: next frontier in understanding human health and development of biotherapeutics. 2011 Biologics pmid:21847343
Jawara M et al. Field testing of different chemical combinations as odour baits for trapping wild mosquitoes in The Gambia. 2011 PLoS ONE pmid:21637337
AbuGhazaleh AA et al. The effect of replacing corn with glycerol on ruminal bacteria in continuous culture fermenters. 2011 J Anim Physiol Anim Nutr (Berl) pmid:20880288
Adams JB et al. Gastrointestinal flora and gastrointestinal status in children with autism--comparisons to typical children and correlation with autism severity. 2011 BMC Gastroenterol pmid:21410934
Hong SM et al. Relationship between the Korean Version of the Sniffin' Stick Test and the T&T Olfactometer in the Korean Population. 2011 Clin Exp Otorhinolaryngol pmid:22232713
Keller A Attention and olfactory consciousness. 2011 Front Psychol pmid:22203813
Xiao W et al. [Functional magnetic resonance imaging of brain activation in early period after olfactory adaptation]. 2011 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22177038
Johnson AJ Cognitive facilitation following intentional odor exposure. 2011 Sensors (Basel) pmid:22163909
Chaudhary P et al. Hydrogen-bonding interactions in T-2 toxin studied using solution and solid-state NMR. 2011 Toxins (Basel) pmid:22069698
Busman M et al. Observation of T-2 toxin and HT-2 toxin glucosides from Fusarium sporotrichioides by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). 2011 Toxins (Basel) pmid:22295176
Ma C et al. Construction of 4"-isovalerylspiramycin-I-producing strain by in-frame partial deletion of 3-O-acyltransferase gene in Streptomyces spiramyceticus WSJ-1, the bitespiramycin producer. 2011 Curr. Microbiol. pmid:20490499
Jo YJ et al. Comparison of fermented soybean paste (Doenjang) prepared by different methods based on profiling of volatile compounds. 2011 J. Food Sci. pmid:21535802
Huang CB et al. Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. 2011 Arch. Oral Biol. pmid:21333271
Scadding G et al. Diagnostic tools in Rhinology EAACI position paper. 2011 Clin Transl Allergy pmid:22410181
Gianelli MP et al. Key aroma components of a dry-cured sausage with high fat content (sobrassada). 2011 Food Sci Technol Int pmid:21364047
Ito N et al. Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. 2011 Evid Based Complement Alternat Med pmid:18955354
Thu TV et al. Effects of liquid metabolite combinations produced by Lactobacillus plantarum on growth performance, faeces characteristics, intestinal morphology and diarrhoea incidence in postweaning piglets. 2011 Trop Anim Health Prod pmid:20632092
Potu RB et al. The effect of lipid supplements on ruminal bacteria in continuous culture fermenters varies with the fatty acid composition. 2011 J. Microbiol. pmid:21538241
Wright KE et al. Inducing mineral precipitation in groundwater by addition of phosphate. 2011 Geochem. Trans. pmid:22029908
Göker M et al. Complete genome sequence of Odoribacter splanchnicus type strain (1651/6). 2011 Stand Genomic Sci pmid:21677857
Kaster AK et al. More than 200 genes required for methane formation from Hâ‚‚ and COâ‚‚ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. 2011 Archaea pmid:21559116
Wilson AD and Baietto M Advances in electronic-nose technologies developed for biomedical applications. 2011 Sensors (Basel) pmid:22346620
Daniotti M et al. New developments in the treatment of hyperammonemia: emerging use of carglumic acid. 2011 Int J Gen Med pmid:21403788
Pimentel GD et al. β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway. 2011 Nutr Metab (Lond) pmid:21345206