| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Maple Syrup Urine Disease | D008375 | 5 associated lipids |
| Acidosis, Renal Tubular | D000141 | 4 associated lipids |
| Fanconi Syndrome | D005198 | 4 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Dwarfism | D004392 | 1 associated lipids |
ISOVALERIC ACID
ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ISOVALERIC ACID?
ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID
PubChem Associated disorders and diseases
What pathways are associated with ISOVALERIC ACID
Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ISOVALERIC ACID?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with ISOVALERIC ACID?
Knock-out
Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with ISOVALERIC ACID
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Van Ziffle J et al. | Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia. | 2011 | PLoS ONE | pmid:21390308 |
| Wroblewska M et al. | Physiological properties of beetroot crisps applied in standard and dyslipidaemic diets of rats. | 2011 | Lipids Health Dis | pmid:21995671 |
| Ensenauer R et al. | Newborn screening for isovaleric acidemia using tandem mass spectrometry: data from 1.6 million newborns. | 2011 | Clin. Chem. | pmid:21335445 |
| Taurino C et al. | Actinoplanes teichomyceticus ATCC 31121 as a cell factory for producing teicoplanin. | 2011 | Microb. Cell Fact. | pmid:22008254 |
| Haskå L et al. | A water-soluble fraction from a by-product of wheat increases the formation of propionic acid in rats compared with diets based on other by-product fractions and oligofructose. | 2011 | Food Nutr Res | pmid:22022302 |
| Adams JB et al. | Gastrointestinal flora and gastrointestinal status in children with autism--comparisons to typical children and correlation with autism severity. | 2011 | BMC Gastroenterol | pmid:21410934 |
| Xiao W et al. | [Functional magnetic resonance imaging of brain activation in early period after olfactory adaptation]. | 2011 | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22177038 |
| Johnson AJ | Cognitive facilitation following intentional odor exposure. | 2011 | Sensors (Basel) | pmid:22163909 |
| Chaudhary P et al. | Hydrogen-bonding interactions in T-2 toxin studied using solution and solid-state NMR. | 2011 | Toxins (Basel) | pmid:22069698 |
| Ma C et al. | Construction of 4"-isovalerylspiramycin-I-producing strain by in-frame partial deletion of 3-O-acyltransferase gene in Streptomyces spiramyceticus WSJ-1, the bitespiramycin producer. | 2011 | Curr. Microbiol. | pmid:20490499 |
| Jo YJ et al. | Comparison of fermented soybean paste (Doenjang) prepared by different methods based on profiling of volatile compounds. | 2011 | J. Food Sci. | pmid:21535802 |
| Huang CB et al. | Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms. | 2011 | Arch. Oral Biol. | pmid:21333271 |
| Gianelli MP et al. | Key aroma components of a dry-cured sausage with high fat content (sobrassada). | 2011 | Food Sci Technol Int | pmid:21364047 |
| Ito N et al. | Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. | 2011 | Evid Based Complement Alternat Med | pmid:18955354 |
| Thu TV et al. | Effects of liquid metabolite combinations produced by Lactobacillus plantarum on growth performance, faeces characteristics, intestinal morphology and diarrhoea incidence in postweaning piglets. | 2011 | Trop Anim Health Prod | pmid:20632092 |
| Potu RB et al. | The effect of lipid supplements on ruminal bacteria in continuous culture fermenters varies with the fatty acid composition. | 2011 | J. Microbiol. | pmid:21538241 |
| Wright KE et al. | Inducing mineral precipitation in groundwater by addition of phosphate. | 2011 | Geochem. Trans. | pmid:22029908 |
| HÃ¥kansson A et al. | Colorectal Oncogenesis and Inflammation in a Rat Model Based on Chronic Inflammation due to Cycling DSS Treatments. | 2011 | Gastroenterol Res Pract | pmid:22007198 |
| Daniotti M et al. | New developments in the treatment of hyperammonemia: emerging use of carglumic acid. | 2011 | Int J Gen Med | pmid:21403788 |
| Pimentel GD et al. | β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway. | 2011 | Nutr Metab (Lond) | pmid:21345206 |