| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Maple Syrup Urine Disease | D008375 | 5 associated lipids |
| Acidosis, Renal Tubular | D000141 | 4 associated lipids |
| Fanconi Syndrome | D005198 | 4 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Dwarfism | D004392 | 1 associated lipids |
ISOVALERIC ACID
ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ISOVALERIC ACID?
ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID
PubChem Associated disorders and diseases
What pathways are associated with ISOVALERIC ACID
Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ISOVALERIC ACID?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Appl. Environ. Microbiol. (4)
- Int. J. Syst. Evol. Microbiol. (3)
- Microbiology (Reading, Engl.) (2)
- Others (10)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with ISOVALERIC ACID?
Knock-out
Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with ISOVALERIC ACID
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Anderson IJ et al. | The complete genome sequence of Staphylothermus marinus reveals differences in sulfur metabolism among heterotrophic Crenarchaeota. | 2009 | BMC Genomics | pmid:19341479 |
| Karnati SK et al. | Investigating unsaturated fat, monensin, or bromoethanesulfonate in continuous cultures retaining ruminal protozoa. I. Fermentation, biohydrogenation, and microbial protein synthesis. | 2009 | J. Dairy Sci. | pmid:19620669 |
| Foroud NA and Eudes F | Trichothecenes in cereal grains. | 2009 | Int J Mol Sci | pmid:19333439 |
| Robin S et al. | Genetic diversity of canine olfactory receptors. | 2009 | BMC Genomics | pmid:19144169 |
| Weng Y et al. | Isovaleric, methylmalonic, and propionic acid decrease anesthetic EC50 in tadpoles, modulate glycine receptor function, and interact with the lipid 1,2-dipalmitoyl-Sn-glycero-3-phosphocholine. | 2009 | Anesth. Analg. | pmid:19372333 |
| Zahorodny Duggan ZP et al. | Distribution and development of the highly specialized lipids in the sound reception systems of dolphins. | 2009 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:19373476 |
| Loots DT | Abnormal tricarboxylic acid cycle metabolites in isovaleric acidaemia. | 2009 | J. Inherit. Metab. Dis. | pmid:19343532 |
| Liu Q et al. | Effects of isovalerate on ruminal fermentation, urinary excretion of purine derivatives and digestibility in steers. | 2009 | J Anim Physiol Anim Nutr (Berl) | pmid:19138353 |
| Van den Velde S et al. | Detection of odorous compounds in breath. | 2009 | J. Dent. Res. | pmid:19329466 |
| Kobayashi E et al. | Functional optical hemodynamic imaging of the olfactory cortex in normosmia subjects and dysosmia subjects. | 2009 | Acta Otolaryngol Suppl | pmid:19848246 |
| Ye FX et al. | Deodorization of swine manure slurry using horseradish peroxidase and peroxides. | 2009 | J. Hazard. Mater. | pmid:19171425 |
| Illmer P and Gstraunthaler G | Effect of seasonal changes in quantities of biowaste on full scale anaerobic digester performance. | 2009 | Waste Manag | pmid:18400485 |
| Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. | 2009 | Orig Life Evol Biosph | pmid:19468860 | |
| Barbosa C et al. | Nitrogen addition influences formation of aroma compounds, volatile acidity and ethanol in nitrogen deficient media fermented by Saccharomyces cerevisiae wine strains. | 2009 | J. Biosci. Bioeng. | pmid:19619854 |
| Aklujkar M et al. | The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens. | 2009 | BMC Microbiol. | pmid:19473543 |
| German DP | Do herbivorous minnows have "plug-flow reactor" guts? Evidence from digestive enzyme activities, gastrointestinal fermentation, and luminal nutrient concentrations. | 2009 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:19363616 |
| Zanor MI et al. | Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. | 2009 | J. Exp. Bot. | pmid:19346240 |
| Akdeniz N et al. | Air sampling and analysis method for volatile organic compounds (VOCs) related to field-scale mortality composting operations. | 2009 | J. Agric. Food Chem. | pmid:19514732 |
| Ntaikou I et al. | Exploitation of olive oil mill wastewater for combined biohydrogen and biopolymers production. | 2009 | Bioresour. Technol. | pmid:19138844 |
| Spiehs MJ and Varel VH | Nutrient excretion and odorant production in manure from cattle fed corn wet distillers grains with solubles. | 2009 | J. Anim. Sci. | pmid:19502500 |