| MeSH term | MeSH ID | Detail |
|---|---|---|
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Liver Cirrhosis, Experimental | D008106 | 36 associated lipids |
| Urination Disorders | D014555 | 9 associated lipids |
| Leukemia | D007938 | 74 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Infarction, Middle Cerebral Artery | D020244 | 35 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Anaphylaxis | D000707 | 35 associated lipids |
Galangin
Galangin is a lipid of Polyketides (PK) class. Galangin is associated with abnormalities such as Morphologically altered structure and Wiskott-Aldrich Syndrome. The involved functions are known as Apoptosis, Metabolic Inhibition, Cell Proliferation, Process and Proliferation (morphologic abnormality). Galangin often locates in Microsomes, Liver, Cytoplasmic matrix, Microsomes, Protoplasm and Tissue membrane. The associated genes with Galangin are CYP1A1 gene, CYP1A2 gene, WNT3A gene, ALPP gene and TCF7L2 gene. The related lipids are Promega.
Cross Reference
Introduction
To understand associated biological information of Galangin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Galangin?
Galangin is suspected in Morphologically altered structure and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Galangin
PubChem Associated disorders and diseases
What pathways are associated with Galangin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Galangin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Galangin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Galangin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Galangin?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Galangin?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Galangin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Maini S et al. | Flavonols Protect Against UV Radiation-Induced Thymine Dimer Formation in an Artificial Skin Mimic. | 2015 | J Pharm Pharm Sci | pmid:26626251 |
| Lau AJ and Chang TK | 3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease. | 2015 | Pharmacol. Res. | pmid:26238175 |
| Choi YJ et al. | Galangin and kaempferol suppress phorbol-12-myristate-13-acetate-induced matrix metalloproteinase-9 expression in human fibrosarcoma HT-1080 cells. | 2015 | Mol. Cells | pmid:25518925 |
| Kerimi A et al. | Modulation of cellular glucose metabolism in human HepG2 cells by combinations of structurally related flavonoids. | 2015 | Mol Nutr Food Res | pmid:25712349 |
| Wu C et al. | Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia. | 2015 | Sci Rep | pmid:26537366 |
| Liu YN et al. | Galangin attenuates airway remodelling by inhibiting TGF-β1-mediated ROS generation and MAPK/Akt phosphorylation in asthma. | 2015 | Sci Rep | pmid:26156213 |
| Luo Q et al. | Protective effect of galangin in Concanavalin A-induced hepatitis in mice. | 2015 | Drug Des Devel Ther | pmid:26089647 |
| Zhao X and Zhang J | [Inhibitory effect of galangin on DNA topoisomerases in lung cancer cells]. | 2015 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | pmid:26032076 |
| Arif H et al. | Mobilization of Copper ions by Flavonoids in Human Peripheral Lymphocytes Leads to Oxidative DNA Breakage: A Structure Activity Study. | 2015 | Int J Mol Sci | pmid:26569217 |
| Tsai MS et al. | Galangin Prevents Acute Hepatorenal Toxicity in Novel Propacetamol-Induced Acetaminophen-Overdosed Mice. | 2015 | J Med Food | pmid:26501381 |
| Chernetsova ES and Morlock GE | Aspects of surface scanning by direct analysis in real time mass spectrometry employing plasma glow visualization. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26395608 |
| Feng WH et al. | Determination of galangin in rat plasma by UPLC and pharmacokinetic study. | 2015 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:26149247 |
| Zeng H et al. | Galangin-induced down-regulation of BACE1 by epigenetic mechanisms in SH-SY5Y cells. | 2015 | Neuroscience | pmid:25779965 |
| Li L et al. | A novel system of galangin-potassium permanganate-polyphosphoric acid for the determination of tryptophan and its chemiluminescence mechanism. | 2015 | Luminescence | pmid:25271024 |
| Carazo Fernández A et al. | Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR). | 2015 | Toxicol. Lett. | pmid:25625231 |
| Ogunbayo OA and Michelangeli F | Related flavonoids cause cooperative inhibition of the sarcoplasmic reticulum Ca²⺠ATPase by multimode mechanisms. | 2014 | FEBS J. | pmid:24238016 |
| Santos EO et al. | Flavonols modulate the effector functions of healthy individuals' immune complex-stimulated neutrophils: a therapeutic perspective for rheumatoid arthritis. | 2014 | Int. Immunopharmacol. | pmid:24797916 |
| Xu L et al. | Identification of luteolin as enterovirus 71 and coxsackievirus A16 inhibitors through reporter viruses and cell viability-based screening. | 2014 | Viruses | pmid:25036464 |
| Gómez-Florit M et al. | Identification of quercitrin as a potential therapeutic agent for periodontal applications. | 2014 | J. Periodontol. | pmid:24548116 |
| Jailani F and Williamson G | Effect of edible oils on quercetin, kaempferol and galangin transport and conjugation in the intestinal Caco-2/HT29-MTX co-culture model. | 2014 | Food Funct | pmid:24525490 |
| Sinha R et al. | In-vitro anti-proliferative and anti-oxidant activity of galangin, fisetin and quercetin: role of localization and intermolecular interaction in model membrane. | 2014 | Eur J Med Chem | pmid:24727463 |
| Zhu L et al. | Galangin inhibits growth of human head and neck squamous carcinoma cells in vitro and in vivo. | 2014 | Chem. Biol. Interact. | pmid:25450235 |
| Wang Y et al. | Galangin suppresses HepG2 cell proliferation by activating the TGF-β receptor/Smad pathway. | 2014 | Toxicology | pmid:25268046 |
| Jung YC et al. | Anti-inflammatory effects of galangin on lipopolysaccharide-activated macrophages via ERK and NF-κB pathway regulation. | 2014 | Immunopharmacol Immunotoxicol | pmid:25270721 |
| Huo SX et al. | The effects of galangin on a mouse model of vitiligo induced by hydroquinone. | 2014 | Phytother Res | pmid:24820380 |
| Shu YS et al. | Galangin dampens mice lipopolysaccharide-induced acute lung injury. | 2014 | Inflammation | pmid:24743919 |
| Choi JK and Kim SH | Inhibitory effect of galangin on atopic dermatitis-like skin lesions. | 2014 | Food Chem. Toxicol. | pmid:24675422 |
| Forbes AM et al. | Structure-activity relationship studies of flavonol analogues on pollen germination. | 2014 | J. Agric. Food Chem. | pmid:24524670 |
| Kawabata K et al. | Flavonols enhanced production of anti-inflammatory substance(s) by Bifidobacterium adolescentis: prebiotic actions of galangin, quercetin, and fisetin. | 2013 Jul-Aug | Biofactors | pmid:23554103 |
| Satué M et al. | Quercitrin and taxifolin stimulate osteoblast differentiation in MC3T3-E1 cells and inhibit osteoclastogenesis in RAW 264.7 cells. | 2013 | Biochem. Pharmacol. | pmid:24060614 |
| Huh JE et al. | The natural flavonoid galangin inhibits osteoclastic bone destruction and osteoclastogenesis by suppressing NF-κB in collagen-induced arthritis and bone marrow-derived macrophages. | 2013 | Eur. J. Pharmacol. | pmid:22985747 |
| Zhang W et al. | Galangin inhibits tumor growth and metastasis of B16F10 melanoma. | 2013 | J. Cell. Biochem. | pmid:22887049 |
| Kumar S and Alagawadi KR | Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats. | 2013 | Pharm Biol | pmid:23363068 |
| Gao J et al. | Analysis of serum metabolites for the discovery of amino acid biomarkers and the effect of galangin on cerebral ischemia. | 2013 | Mol Biosyst | pmid:23793526 |
| Wang X et al. | Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model. | 2013 | Environ. Toxicol. Pharmacol. | pmid:23686009 |
| Navarro-Navarro M et al. | Antibacterial activity of Sonoran propolis and some of its constituents against clinically significant Vibrio species. | 2013 | Foodborne Pathog. Dis. | pmid:23351031 |
| Kim HH et al. | Galangin attenuates mast cell-mediated allergic inflammation. | 2013 | Food Chem. Toxicol. | pmid:23535185 |
| Ha TK et al. | Galangin induces human colon cancer cell death via the mitochondrial dysfunction and caspase-dependent pathway. | 2013 | Exp. Biol. Med. (Maywood) | pmid:23925650 |
| Descamps O et al. | AβPP-selective BACE inhibitors (ASBI): novel class of therapeutic agents for alzheimer's disease. | 2013 | J. Alzheimers Dis. | pmid:23948888 |
| Zhang H et al. | Galangin inhibits proliferation of HepG2 cells by activating AMPK via increasing the AMP/TAN ratio in a LKB1-independent manner. | 2013 | Eur. J. Pharmacol. | pmid:24028940 |
| Su L et al. | Galangin inhibits proliferation of hepatocellular carcinoma cells by inducing endoplasmic reticulum stress. | 2013 | Food Chem. Toxicol. | pmid:24161691 |
| Pavlović AV et al. | Chemical composition of two different extracts of berries harvested in Serbia. | 2013 | J. Agric. Food Chem. | pmid:23600608 |
| Nie P et al. | Application of visible and near infrared spectroscopy for rapid analysis of chrysin and galangin in Chinese propolis. | 2013 | Sensors (Basel) | pmid:23945741 |
| Gomes A et al. | Trihydroxyflavones with antioxidant and anti-inflammatory efficacy. | 2012 Sep-Oct | Biofactors | pmid:22806885 |
| Bertelli D et al. | ¹H-NMR simultaneous identification of health-relevant compounds in propolis extracts. | 2012 May-Jun | Phytochem Anal | pmid:21853496 |
| Bisogni S et al. | Influence of oxidative stress on inducing micturition dysfunction following chronic infravesical obstruction and the protective role of an antioxidant diet - association of in vivo and in vitro studies in rats. | 2012 Jul-Aug | Int Braz J Urol | pmid:22951166 |
| Kim DA et al. | Galangin induces apoptosis in gastric cancer cells via regulation of ubiquitin carboxy-terminal hydrolase isozyme L1 and glutathione S-transferase P. | 2012 | Food Chem. Toxicol. | pmid:22142694 |
| Jung CH et al. | Alpinia officinarum inhibits adipocyte differentiation and high-fat diet-induced obesity in mice through regulation of adipogenesis and lipogenesis. | 2012 | J Med Food | pmid:23126661 |
| Zhong L et al. | Antimicrobial flavonoids from the twigs of Populus nigra x Populus deltoides. | 2012 | Nat. Prod. Res. | pmid:21416454 |
| Li S et al. | By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke. | 2012 | Molecules | pmid:23143152 |