Leukotriene b4
Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.
Cross Reference
Introduction
To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Leukotriene b4?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Leukotriene b4
PubChem Associated disorders and diseases
What pathways are associated with Leukotriene b4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Leukotriene b4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Leukotriene b4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Leukotriene b4?
There are no associated biomedical information in the current reference collection.
What genes are associated with Leukotriene b4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Leukotriene b4?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Leukotriene b4
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|---|---|---|---|---|
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| Vincent WJB et al. | Neutrophil derived LTB4 induces macrophage aggregation in response to encapsulated Streptococcus iniae infection. | 2017 | PLoS ONE | pmid:28658259 |
| Tu ZL et al. | LTB4 and montelukast in transplantation-related bronchiolitis obliterans in rats. | 2017 | J Cardiothorac Surg | pmid:28545478 |
| Yu XH et al. | Biomarkers of unstable angina pectoris and yangxin decoction intervention: An exploratory metabonomics study of blood plasma. | 2017 | Medicine (Baltimore) | pmid:28538412 |
| Hamilton KD et al. | Natural products isolated from Tetragonula carbonaria cerumen modulate free radical-scavenging and 5-lipoxygenase activities in vitro. | 2017 | BMC Complement Altern Med | pmid:28446157 |
| Al-Roujayee AS | Naringenin improves the healing process of thermally-induced skin damage in rats. | 2017 | J. Int. Med. Res. | pmid:28415935 |
| Ying W et al. | Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. | 2017 | J. Clin. Invest. | pmid:28192375 |
| Archambault AS et al. | Leukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In Cellulo. | 2017 | PLoS ONE | pmid:28068410 |
| Min A et al. | SNAP23-Dependent Surface Translocation of Leukotriene B4 (LTB4) Receptor 1 Is Essential for NOX2-Mediated Exocytotic Degranulation in Human Mast Cells Induced by Trichomonas vaginalis-Secreted LTB4. | 2017 | Infect. Immun. | pmid:27795355 |
| Spilker ME et al. | Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies. | 2017 | Xenobiotica | pmid:27435693 |
| Zhou X et al. | Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. | 2017 | Mol Med Rep | pmid:28358431 |
| Singh A et al. | Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia. | 2017 | J. Leukoc. Biol. | pmid:27630217 |
| Pallio G et al. | Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis. | 2016 | Eur. J. Pharmacol. | pmid:27450484 |
| Pruzanski W et al. | Hydrolysis of lipoproteins by sPLA2's enhances mitogenesis and eicosanoid release from vascular smooth muscle cells: Diverse activity of sPLA2's IIA, V and X. | 2016 | Prostaglandins Other Lipid Mediat. | pmid:26711221 |
| Pontes AS et al. | p38 MAPK is involved in human neutrophil chemotaxis induced by L-amino acid oxidase from Calloselasma rhodosthoma. | 2016 | Toxicon | pmid:27242041 |
| Pedruzzi G et al. | Understanding PGE2, LXA4 and LTB4 balance during Mycobacterium tuberculosis infection through mathematical model. | 2016 | J. Theor. Biol. | pmid:26551160 |
| Jung KH et al. | Protective Effects of Intratracheally-Administered Bee Venom Phospholipase A2 on Ovalbumin-Induced Allergic Asthma in Mice. | 2016 | Toxins (Basel) | pmid:27669297 |
| Yoshida S et al. | Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. | 2016 | J. Med. Invest. | pmid:27644556 |
| Chaves MM et al. | Crosstalk between purinergic receptors and lipid mediators in leishmaniasis. | 2016 | Parasit Vectors | pmid:27595742 |
| Sun D and Shi M | Neutrophil swarming toward Cryptococcus neoformans is mediated by complement and leukotriene B4. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27402276 |
| Ee MT et al. | Leukotriene B4 mediates macrophage influx and pulmonary hypertension in bleomycin-induced chronic neonatal lung injury. | 2016 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:27317685 |
| Maddipati KR et al. | Lipidomic analysis of patients with microbial invasion of the amniotic cavity reveals up-regulation of leukotriene B4. | 2016 | FASEB J. | pmid:27312808 |
| Gall BJ et al. | Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model. | 2016 | Genes Immun. | pmid:27307211 |
| Marvar PJ et al. | Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat. | 2016 | J. Physiol. (Lond.) | pmid:27230966 |
| Elias I et al. | ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance. | 2016 | Diabetes | pmid:27207555 |
| Zoccal KF et al. | Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality. | 2016 | Nat Commun | pmid:26907476 |
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| Majumdar R et al. | Exosomes Mediate LTB4 Release during Neutrophil Chemotaxis. | 2016 | PLoS Biol. | pmid:26741884 |
| Dong R et al. | Cigarette smoke-induced lung inflammation in COPD mediated via LTB4/BLT1/SOCS1 pathway. | 2016 | Int J Chron Obstruct Pulmon Dis | pmid:26730186 |
| Havixbeck JJ et al. | Neutrophil contributions to the induction and regulation of the acute inflammatory response in teleost fish. | 2016 | J. Leukoc. Biol. | pmid:26292979 |
| Su HH et al. | Aryl hydrocarbon receptor-ligand axis mediates pulmonary fibroblast migration and differentiation through increased arachidonic acid metabolism. | 2016 | Toxicology | pmid:27697457 |
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| Vaivoda R et al. | CYP4F18-Deficient Neutrophils Exhibit Increased Chemotaxis to Complement Component C5a. | 2015 | J Immunol Res | pmid:26613087 |
| Homann J et al. | In Vivo Availability of Pro-Resolving Lipid Mediators in Oxazolone Induced Dermal Inflammation in the Mouse. | 2015 | PLoS ONE | pmid:26599340 |
| Liu X et al. | Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells. | 2015 | Cell. Physiol. Biochem. | pmid:26584289 |
| Qian J et al. | Leukotriene B4 Activates Pulmonary Artery Adventitial Fibroblasts in Pulmonary Hypertension. | 2015 | Hypertension | pmid:26558820 |
| Rodrigues IA et al. | Natural Products: Insights into Leishmaniasis Inflammatory Response. | 2015 | Mediators Inflamm. | pmid:26538837 |
| Knab LM et al. | Ablation of 5-lipoxygenase mitigates pancreatic lesion development. | 2015 | J. Surg. Res. | pmid:25454978 |
| Zoccal KF et al. | PPAR-γ activation by Tityus serrulatus venom regulates lipid body formation and lipid mediator production. | 2015 | Toxicon | pmid:25450800 |
| Gendelman O et al. | A randomized double-blind placebo-controlled study adding high dose vitamin D to analgesic regimens in patients with musculoskeletal pain. | 2015 | Lupus | pmid:25801891 |
| Hoffmeyer F et al. | Evaluation of Airway Inflammation in Compost Workers Exposed to Bioaerosols Using Exhaled Breath Condensate and Fractional Exhaled Nitric Oxide. | 2015 | Adv. Exp. Med. Biol. | pmid:25786401 |