Leukotriene b4

Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.

Cross Reference

Introduction

To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Leukotriene b4

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Hypoxia D000860 23 associated lipids
Adenocarcinoma D000230 166 associated lipids
Enterocolitis D004760 3 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Mycobacterium Infections D009164 7 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Sarcoidosis D012507 13 associated lipids
Wounds and Injuries D014947 20 associated lipids
Pleurisy D010998 20 associated lipids
Burns D002056 34 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Intestinal Diseases D007410 6 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Carcinoma D002277 18 associated lipids
Gastritis D005756 27 associated lipids
Pulmonary Edema D011654 23 associated lipids
Joint Dislocations D004204 2 associated lipids
Ureteral Obstruction D014517 10 associated lipids
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Liver Cirrhosis, Experimental D008106 36 associated lipids
Hypersensitivity D006967 22 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Leukotriene b4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Leukotriene b4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Leukotriene b4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

What genes are associated with Leukotriene b4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Leukotriene b4

Download all related citations
Per page 10 20 50 100 | Total 5221
Authors Title Published Journal PubMed Link
Marvar PJ et al. Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat. 2016 J. Physiol. (Lond.) pmid:27230966
Pazos MA et al. Distinct cellular sources of hepoxilin A3 and leukotriene B4 are used to coordinate bacterial-induced neutrophil transepithelial migration. 2015 J. Immunol. pmid:25548217
Li P et al. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. 2015 Nat. Med. pmid:25706874
Filgueiras LR et al. Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes. 2015 Sci Signal pmid:25628460
Tateishi N et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. 2015 Lipids Health Dis pmid:25595700
Fahel JS et al. 5-Lipoxygenase negatively regulates Th1 response during Brucella abortus infection in mice. 2015 Infect. Immun. pmid:25583526
Liu M and Yokomizo T The role of leukotrienes in allergic diseases. 2015 Allergol Int pmid:25572555
Dalli J et al. The Regulation of Proresolving Lipid Mediator Profiles in Baboon Pneumonia by Inhaled Carbon Monoxide. 2015 Am. J. Respir. Cell Mol. Biol. pmid:25568926
Piotrowska-Tomala KK et al. Lipopolysaccharides, cytokines, and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland during experimentally induced mastitis in vivo and in vitro. 2015 Domest. Anim. Endocrinol. pmid:25935895
Minutoli L et al. A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury. 2015 Neuromolecular Med. pmid:25893744