Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.
To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with Leukotriene b4
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Bitto A et al. | Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice. | 2017 | Inflamm. Res. | pmid:28238167 |
Sasaki F et al. | Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1. | 2017 | PLoS ONE | pmid:28922396 |
Pazos MA et al. | Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration. | 2017 | PLoS Pathog. | pmid:28771621 |
Heineke MH et al. | Peptide mimetics of immunoglobulin A (IgA) and FcαRI block IgA-induced human neutrophil activation and migration. | 2017 | Eur. J. Immunol. | pmid:28736835 |
Ying W et al. | Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. | 2017 | J. Clin. Invest. | pmid:28192375 |
Archambault AS et al. | Leukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In Cellulo. | 2017 | PLoS ONE | pmid:28068410 |
Min A et al. | SNAP23-Dependent Surface Translocation of Leukotriene B4 (LTB4) Receptor 1 Is Essential for NOX2-Mediated Exocytotic Degranulation in Human Mast Cells Induced by Trichomonas vaginalis-Secreted LTB4. | 2017 | Infect. Immun. | pmid:27795355 |
Spilker ME et al. | Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies. | 2017 | Xenobiotica | pmid:27435693 |
Zhou X et al. | Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. | 2017 | Mol Med Rep | pmid:28358431 |
Singh A et al. | Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia. | 2017 | J. Leukoc. Biol. | pmid:27630217 |