Leukotriene b4

Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin.

Cross Reference

Introduction

To understand associated biological information of Leukotriene b4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Leukotriene b4

MeSH term MeSH ID Detail
Vomiting D014839 21 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Respiratory Hypersensitivity D012130 18 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Agranulocytosis D000380 7 associated lipids
Shock D012769 11 associated lipids
Erythema D004890 22 associated lipids
Polycythemia Vera D011087 13 associated lipids
Mucocutaneous Lymph Node Syndrome D009080 9 associated lipids
Otitis D010031 5 associated lipids
Dermatomycoses D003881 17 associated lipids
Hyperalgesia D006930 42 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Anaphylaxis D000707 35 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Pneumococcal Infections D011008 7 associated lipids
Bronchial Spasm D001986 18 associated lipids
Hyperlipidemias D006949 73 associated lipids
Bronchitis D001991 6 associated lipids
Immune Complex Diseases D007105 9 associated lipids
Chorioamnionitis D002821 5 associated lipids
Obstetric Labor, Premature D007752 9 associated lipids
Coronary Artery Disease D003324 47 associated lipids
Cough D003371 19 associated lipids
Hearing Disorders D006311 10 associated lipids
Translocation, Genetic D014178 20 associated lipids
Cholera D002771 6 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Metaplasia D008679 7 associated lipids
Silicosis D012829 3 associated lipids
Status Asthmaticus D013224 4 associated lipids
Neutropenia D009503 15 associated lipids
Extravasation of Diagnostic and Therapeutic Materials D005119 3 associated lipids
Rhinitis, Allergic, Perennial D012221 6 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Cluster Headache D003027 4 associated lipids
Purpura, Schoenlein-Henoch D011695 5 associated lipids
Abetalipoproteinemia D000012 7 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Respiratory Tract Infections D012141 4 associated lipids
Gastrointestinal Hemorrhage D006471 27 associated lipids
HIV Seropositivity D006679 15 associated lipids
Uveitis D014605 14 associated lipids
Murine Acquired Immunodeficiency Syndrome D016183 2 associated lipids
Byssinosis D002095 11 associated lipids
Adenoma D000236 40 associated lipids
Pneumonia, Aspiration D011015 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Leukotriene b4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Leukotriene b4?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Leukotriene b4?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

What genes are associated with Leukotriene b4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Leukotriene b4?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Leukotriene b4

Download all related citations
Per page 10 20 50 100 | Total 5221
Authors Title Published Journal PubMed Link
Bitto A et al. Effects of COX1-2/5-LOX blockade in Alzheimer transgenic 3xTg-AD mice. 2017 Inflamm. Res. pmid:28238167
Sasaki F et al. Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1. 2017 PLoS ONE pmid:28922396
Hamilton KD et al. Natural products isolated from Tetragonula carbonaria cerumen modulate free radical-scavenging and 5-lipoxygenase activities in vitro. 2017 BMC Complement Altern Med pmid:28446157
Al-Roujayee AS Naringenin improves the healing process of thermally-induced skin damage in rats. 2017 J. Int. Med. Res. pmid:28415935
Ying W et al. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. 2017 J. Clin. Invest. pmid:28192375
Archambault AS et al. Leukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In Cellulo. 2017 PLoS ONE pmid:28068410
Min A et al. SNAP23-Dependent Surface Translocation of Leukotriene B4 (LTB4) Receptor 1 Is Essential for NOX2-Mediated Exocytotic Degranulation in Human Mast Cells Induced by Trichomonas vaginalis-Secreted LTB4. 2017 Infect. Immun. pmid:27795355
Spilker ME et al. Leveraging model-based study designs and serial micro-sampling techniques to understand the oral pharmacokinetics of the potent LTB4 inhibitor, CP-105696, for mouse pharmacology studies. 2017 Xenobiotica pmid:27435693
Zhou X et al. Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. 2017 Mol Med Rep pmid:28358431
Singh A et al. Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia. 2017 J. Leukoc. Biol. pmid:27630217